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Molecules 2012, 17(5), 5924-5934; doi:10.3390/molecules17055924
Article

Scope and Limitations of a Novel Synthesis of 3-Arylazonicotinates

1,* , 2,* , 1, 1 and 2
Received: 27 January 2012; in revised form: 13 May 2012 / Accepted: 15 May 2012 / Published: 18 May 2012
(This article belongs to the Special Issue Heterocycles)
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Abstract: The reaction of 3-oxo-3-phenyl-2-phenylhydrazonal with functionally substituted and heteroaromatic substituted acetonitrile to yield arylazonicotinic acid derivatives and 5-arylsubstituted pyridines was established. In some cases the produced nicotinates could not be isolated as they underwent thermally induced 6π-electrocyclization yielding polynuclear pyridine derivatives.
Keywords: 3-oxo-3-phenyl-2-phenylhydrazonal; arylazonicotinic acid; pyridine; electrocyclization; heteroaromatics 3-oxo-3-phenyl-2-phenylhydrazonal; arylazonicotinic acid; pyridine; electrocyclization; heteroaromatics
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Zaky, O.S.; Moustafa, M.S.; Selim, M.A.; El-Maghraby, A.M.; Elnagdi, M.H. Scope and Limitations of a Novel Synthesis of 3-Arylazonicotinates. Molecules 2012, 17, 5924-5934.

AMA Style

Zaky OS, Moustafa MS, Selim MA, El-Maghraby AM, Elnagdi MH. Scope and Limitations of a Novel Synthesis of 3-Arylazonicotinates. Molecules. 2012; 17(5):5924-5934.

Chicago/Turabian Style

Zaky, Omniya Sayed; Moustafa, Moustafa Sherief; Selim, Maghraby Ali; El-Maghraby, Awatef Mohamed; Elnagdi, Mohamed Hilmy. 2012. "Scope and Limitations of a Novel Synthesis of 3-Arylazonicotinates." Molecules 17, no. 5: 5924-5934.


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