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Molecules 2012, 17(5), 5467-5496; doi:10.3390/molecules17055467
Review

Solid-Phase Parallel Synthesis of Drug-Like Artificial 2H-Benzopyran Libraries

1
 and 2,*
Received: 10 April 2012; in revised form: 25 April 2012 / Accepted: 7 May 2012 / Published: 9 May 2012
(This article belongs to the Special Issue Solid Phase Synthesis)
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Abstract: This review covers the construction of drug-like 2H-benzopyrans and related libraries using solid-phase parallel synthesis. In this context, the preparation of substituted benzopyrans such as mono-, di- and trisubstituted benzopyran derivatives and additional ring-fused benzopyrans such as benzopyranoisoxazoles, benzopyranopyrazoles, six-membered ring-fused benzopyrans, and polycyclic benzopyrans are highlighted.
Keywords: combinatorial chemistry; solid-phase synthesis; chemical library; drug-like molecules; 2H-benzopyran combinatorial chemistry; solid-phase synthesis; chemical library; drug-like molecules; 2H-benzopyran
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Lee, T.; Gong, Y.-D. Solid-Phase Parallel Synthesis of Drug-Like Artificial 2H-Benzopyran Libraries. Molecules 2012, 17, 5467-5496.

AMA Style

Lee T, Gong Y-D. Solid-Phase Parallel Synthesis of Drug-Like Artificial 2H-Benzopyran Libraries. Molecules. 2012; 17(5):5467-5496.

Chicago/Turabian Style

Lee, Taeho; Gong, Young-Dae. 2012. "Solid-Phase Parallel Synthesis of Drug-Like Artificial 2H-Benzopyran Libraries." Molecules 17, no. 5: 5467-5496.


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