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Molecules 2012, 17(5), 5003-5012; doi:10.3390/molecules17055003

Hydrophilic Carotenoids: Recent Progress

, ,  and *
Department of Biochemistry and Medical Chemistry, University of Pécs, Medical School, Szigeti út 12, H-7624 Pécs, Hungary
* Author to whom correspondence should be addressed.
Received: 22 March 2012 / Revised: 17 April 2012 / Accepted: 19 April 2012 / Published: 30 April 2012
(This article belongs to the Special Issue Carotenoids)
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Carotenoids are substantially hydrophobic antioxidants. Hydrophobicity is this context is rather a disadvantage, because their utilization in medicine as antioxidants or in food chemistry as colorants would require some water dispersibility for their effective uptake or use in many other ways. In the past 15 years several attempts were made to synthetize partially hydrophilic carotenoids. This review compiles the recently synthetized hydrophilic carotenoid derivatives.
Keywords: carotenoids; hydrophilic; esterification; PEG conjugates; cycloaddition carotenoids; hydrophilic; esterification; PEG conjugates; cycloaddition
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Háda, M.; Nagy, V.; Deli, J.; Agócs, A. Hydrophilic Carotenoids: Recent Progress. Molecules 2012, 17, 5003-5012.

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