Oligonucleotide-Templated Reactions for Sensing Nucleic Acids

doi:10.3390/molecules17032446

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Molecules 2012, 17(3), 2446-2463; doi:10.3390/molecules17032446

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Oligonucleotide-Templated Reactions for Sensing Nucleic Acids

Aya Shibata, Hiroshi Abe* and Yoshihiro Ito

Nano Medical Engineering Laboratory, RIKEN Advanced Science Institute 2-1, Hirosawa, Wako-Shi, Saitama 351-0198, Japan

* Author to whom correspondence should be addressed.

Received: 10 February 2012; in revised form: 23 February 2012 / Accepted: 24 February 2012 / Published: 29 February 2012

(This article belongs to the Special Issue DNA-Templated Synthesis)

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Abstract: Oligonucleotide-templated reactions are useful for applying nucleic acid sensing. Various chemistries for oligonucleotide-templated reaction have been reported so far. Major scientific interests are focused on the development of signal amplification systems and signal generation systems. We introduce the recent advances of oligonucleotide-templated reaction in consideration of the above two points.

Keywords: detection; amplification; fluorescence; DNA; protein nucleic acid; RNA

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MDPI and ACS Style

Shibata, A.; Abe, H.; Ito, Y. Oligonucleotide-Templated Reactions for Sensing Nucleic Acids. Molecules 2012, 17, 2446-2463.

AMA Style

Shibata A, Abe H, Ito Y. Oligonucleotide-Templated Reactions for Sensing Nucleic Acids. Molecules. 2012; 17(3):2446-2463.

Chicago/Turabian Style

Shibata, Aya; Abe, Hiroshi; Ito, Yoshihiro. 2012. "Oligonucleotide-Templated Reactions for Sensing Nucleic Acids." Molecules 17, no. 3: 2446-2463.

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