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Molecules 2012, 17(3), 2446-2463; doi:10.3390/molecules17032446
Review

Oligonucleotide-Templated Reactions for Sensing Nucleic Acids

,
*  and
Nano Medical Engineering Laboratory, RIKEN Advanced Science Institute 2-1, Hirosawa, Wako-Shi, Saitama 351-0198, Japan
* Author to whom correspondence should be addressed.
Received: 10 February 2012 / Revised: 23 February 2012 / Accepted: 24 February 2012 / Published: 29 February 2012
(This article belongs to the Special Issue DNA-Templated Synthesis)
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Abstract

Oligonucleotide-templated reactions are useful for applying nucleic acid sensing. Various chemistries for oligonucleotide-templated reaction have been reported so far. Major scientific interests are focused on the development of signal amplification systems and signal generation systems. We introduce the recent advances of oligonucleotide-templated reaction in consideration of the above two points.
Keywords: detection; amplification; fluorescence; DNA; protein nucleic acid; RNA detection; amplification; fluorescence; DNA; protein nucleic acid; RNA
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).
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Shibata, A.; Abe, H.; Ito, Y. Oligonucleotide-Templated Reactions for Sensing Nucleic Acids. Molecules 2012, 17, 2446-2463.

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