Molecules 2012, 17(12), 14099-14110; doi:10.3390/molecules171214099
Communication

Allylation of Functionalized Aldehydes by Potassium Allyltrifluoroborate Catalyzed by 18-Crown-6 in Aqueous Media

Fernanda C. G. Barbosa, Juliano C. R. Freitas, Caio F. Melo, Paulo H. Menezes and Roberta A. Oliveira* email
Departamento de Química Fundamental, Universidade Federal de Pernambuco, Av. Jornalista Aníbal Fernandes, s/n - Cidade Universitária, Recife – PE, 50740-560, Brazil
* Author to whom correspondence should be addressed.
Received: 25 September 2012; in revised form: 19 November 2012 / Accepted: 23 November 2012 / Published: 28 November 2012
(This article belongs to the Section Organic Synthesis)
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Abstract: An efficient method for the allylation of aldehydes containing a broad range of functional groups using potassium allyltrifluoroborate is described. The reaction utilizes a catalytic amount of 18-C-6 in biphasic media under open atmosphere and room temperature to provide the corresponding homoallylic alcohols in high yields and without the necessity of any subsequent purification.
Keywords: potassium allyltrifluoroborate; allylation; 18-crown-6

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MDPI and ACS Style

Barbosa, F.C.G.; Freitas, J.C.R.; Melo, C.F.; Menezes, P.H.; Oliveira, R.A. Allylation of Functionalized Aldehydes by Potassium Allyltrifluoroborate Catalyzed by 18-Crown-6 in Aqueous Media. Molecules 2012, 17, 14099-14110.

AMA Style

Barbosa FCG, Freitas JCR, Melo CF, Menezes PH, Oliveira RA. Allylation of Functionalized Aldehydes by Potassium Allyltrifluoroborate Catalyzed by 18-Crown-6 in Aqueous Media. Molecules. 2012; 17(12):14099-14110.

Chicago/Turabian Style

Barbosa, Fernanda C.G.; Freitas, Juliano C.R.; Melo, Caio F.; Menezes, Paulo H.; Oliveira, Roberta A. 2012. "Allylation of Functionalized Aldehydes by Potassium Allyltrifluoroborate Catalyzed by 18-Crown-6 in Aqueous Media." Molecules 17, no. 12: 14099-14110.

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