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Molecules 2012, 17(1), 295-302; doi:10.3390/molecules17010295

A New Triterpenoid Saponin from Abrus precatorius Linn

1 Key Laboratory of Marine Bio-Resources Sustainable Utilization, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, China 2 Graduate University of Chinese Academy of Sciences, 19 Yuquan Road, Beijing 100049, China 3 Department of Biochemistry and Molecular Biology, College of Basic Medical Sciences, Second Military Medical University, Shanghai 200433, China
* Author to whom correspondence should be addressed.
Received: 30 November 2011 / Revised: 20 December 2011 / Accepted: 23 December 2011 / Published: 30 December 2011
(This article belongs to the Section Metabolites)
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A new triterpenoid saponin, 3-O-β-D-glucopyranosyl-(1→2)-β-D-glucopyranosyl subprogenin D (1), together with six known triterpenoids: subprogenin D (2), abrusgenic acid (3), triptotriterpenic acid B (4), abruslactone A (5), abrusogenin (6) and abrusoside C (7) were isolated from the leaves and stems of Abrus precatorius. Their structures were elucidated on the basis of physical and NMR analysis, respectively. Compounds 5 and 6 showed moderate cytotoxicity against MCF-7, SW1990, Hela, and Du-145 cell lines. Compounds 1, 2 and 4 were isolated from this plant for the first time.
Keywords: Abrus precarorius Linn; triterpenoid; saponin; cytotoxicity Abrus precarorius Linn; triterpenoid; saponin; cytotoxicity
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Xiao, Z.-H.; Wang, F.-Z.; Sun, A.-J.; Li, C.-R.; Huang, C.-G.; Zhang, S. A New Triterpenoid Saponin from Abrus precatorius Linn. Molecules 2012, 17, 295-302.

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