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Molecules 2012, 17(1), 295-302; doi:10.3390/molecules17010295

A New Triterpenoid Saponin from Abrus precatorius Linn

1 Key Laboratory of Marine Bio-Resources Sustainable Utilization, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, China 2 Graduate University of Chinese Academy of Sciences, 19 Yuquan Road, Beijing 100049, China 3 Department of Biochemistry and Molecular Biology, College of Basic Medical Sciences, Second Military Medical University, Shanghai 200433, China
* Author to whom correspondence should be addressed.
Received: 30 November 2011 / Revised: 20 December 2011 / Accepted: 23 December 2011 / Published: 30 December 2011
(This article belongs to the Section Natural Products)
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A new triterpenoid saponin, 3-O-β-D-glucopyranosyl-(1→2)-β-D-glucopyranosyl subprogenin D (1), together with six known triterpenoids: subprogenin D (2), abrusgenic acid (3), triptotriterpenic acid B (4), abruslactone A (5), abrusogenin (6) and abrusoside C (7) were isolated from the leaves and stems of Abrus precatorius. Their structures were elucidated on the basis of physical and NMR analysis, respectively. Compounds 5 and 6 showed moderate cytotoxicity against MCF-7, SW1990, Hela, and Du-145 cell lines. Compounds 1, 2 and 4 were isolated from this plant for the first time.
Keywords: Abrus precarorius Linn; triterpenoid; saponin; cytotoxicity Abrus precarorius Linn; triterpenoid; saponin; cytotoxicity
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Xiao, Z.-H.; Wang, F.-Z.; Sun, A.-J.; Li, C.-R.; Huang, C.-G.; Zhang, S. A New Triterpenoid Saponin from Abrus precatorius Linn. Molecules 2012, 17, 295-302.

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