Molecules 2012, 17(1), 295-302; doi:10.3390/molecules17010295
Article

A New Triterpenoid Saponin from Abrus precatorius Linn

Zhi-Hui Xiao 1,2 email, Fa-Zuo Wang 1 email, Ai-Jun Sun 1 email, Chuan-Rong Li 1 email, Cai-Guo Huang 3 email and Si Zhang 1,* email
1 Key Laboratory of Marine Bio-Resources Sustainable Utilization, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, China 2 Graduate University of Chinese Academy of Sciences, 19 Yuquan Road, Beijing 100049, China 3 Department of Biochemistry and Molecular Biology, College of Basic Medical Sciences, Second Military Medical University, Shanghai 200433, China
* Author to whom correspondence should be addressed.
Received: 30 November 2011; in revised form: 20 December 2011 / Accepted: 23 December 2011 / Published: 30 December 2011
(This article belongs to the Section Natural Products)
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Abstract: A new triterpenoid saponin, 3-O-β-D-glucopyranosyl-(1→2)-β-D-glucopyranosyl subprogenin D (1), together with six known triterpenoids: subprogenin D (2), abrusgenic acid (3), triptotriterpenic acid B (4), abruslactone A (5), abrusogenin (6) and abrusoside C (7) were isolated from the leaves and stems of Abrus precatorius. Their structures were elucidated on the basis of physical and NMR analysis, respectively. Compounds 5 and 6 showed moderate cytotoxicity against MCF-7, SW1990, Hela, and Du-145 cell lines. Compounds 1, 2 and 4 were isolated from this plant for the first time.
Keywords: Abrus precarorius Linn; triterpenoid; saponin; cytotoxicity

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Cite This Article

MDPI and ACS Style

Xiao, Z.-H.; Wang, F.-Z.; Sun, A.-J.; Li, C.-R.; Huang, C.-G.; Zhang, S. A New Triterpenoid Saponin from Abrus precatorius Linn. Molecules 2012, 17, 295-302.

AMA Style

Xiao Z-H, Wang F-Z, Sun A-J, Li C-R, Huang C-G, Zhang S. A New Triterpenoid Saponin from Abrus precatorius Linn. Molecules. 2012; 17(1):295-302.

Chicago/Turabian Style

Xiao, Zhi-Hui; Wang, Fa-Zuo; Sun, Ai-Jun; Li, Chuan-Rong; Huang, Cai-Guo; Zhang, Si. 2012. "A New Triterpenoid Saponin from Abrus precatorius Linn." Molecules 17, no. 1: 295-302.

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