Next Article in Journal
Enantiomeric Separation and Determination of the Enantiomeric Impurity of Armodafinil by Capillary Electrophoresis with Sulfobutyl Ether-β-cyclodextrin as Chiral Selector
Previous Article in Journal
Estimation of Dermatological Application of Creams with St. John’s Wort Oil Extracts
Molecules 2012, 17(1), 295-302; doi:10.3390/molecules17010295
Article

A New Triterpenoid Saponin from Abrus precatorius Linn

1,2
,
1
,
1
,
1
,
3
 and
1,*
1 Key Laboratory of Marine Bio-Resources Sustainable Utilization, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, China 2 Graduate University of Chinese Academy of Sciences, 19 Yuquan Road, Beijing 100049, China 3 Department of Biochemistry and Molecular Biology, College of Basic Medical Sciences, Second Military Medical University, Shanghai 200433, China
* Author to whom correspondence should be addressed.
Received: 30 November 2011 / Revised: 20 December 2011 / Accepted: 23 December 2011 / Published: 30 December 2011
(This article belongs to the Section Natural Products)
Download PDF [241 KB, 18 June 2014; original version 18 June 2014]

Abstract

A new triterpenoid saponin, 3-O-β-D-glucopyranosyl-(1→2)-β-D-glucopyranosyl subprogenin D (1), together with six known triterpenoids: subprogenin D (2), abrusgenic acid (3), triptotriterpenic acid B (4), abruslactone A (5), abrusogenin (6) and abrusoside C (7) were isolated from the leaves and stems of Abrus precatorius. Their structures were elucidated on the basis of physical and NMR analysis, respectively. Compounds 5 and 6 showed moderate cytotoxicity against MCF-7, SW1990, Hela, and Du-145 cell lines. Compounds 1, 2 and 4 were isolated from this plant for the first time.
Keywords: Abrus precarorius Linn; triterpenoid; saponin; cytotoxicity Abrus precarorius Linn; triterpenoid; saponin; cytotoxicity
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).
SciFeed

Share & Cite This Article

Further Mendeley | CiteULike
Export to BibTeX |
EndNote |
RIS
MDPI and ACS Style

Xiao, Z.-H.; Wang, F.-Z.; Sun, A.-J.; Li, C.-R.; Huang, C.-G.; Zhang, S. A New Triterpenoid Saponin from Abrus precatorius Linn. Molecules 2012, 17, 295-302.

View more citation formats

Related Articles

Article Metrics

For more information on the journal, click here

Comments

[Return to top]
Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert