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Molecules 2011, 16(9), 8053-8061; doi:10.3390/molecules16098053
Article

A Short Synthesis of Bisabolane Sesquiterpenes

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Received: 31 August 2011; in revised form: 4 September 2011 / Accepted: 14 September 2011 / Published: 19 September 2011
(This article belongs to the Special Issue Terpenoids)
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Abstract: A facile total synthesis of three members of the bisabolane sesquiterpene family, namely (±)-curcumene, (±)-xanthorrhizol and (±)-curcuhydroquinone had been achieved in high overall yield. The synthesis used bromobenzene derivatives as starting materials. The halogen-lithium exchange followed by addition of isoprenylacetone and reduction of the obtained carbinols are the key steps of the synthetic pathway. This synthetic approach provides a new route to the bisabolane sesquiterpenes.
Keywords: curcumene; xanthorrhizol; curcuhydroquinone; synthesis curcumene; xanthorrhizol; curcuhydroquinone; synthesis
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Du, Z.-T.; Zheng, S.; Chen, G.; Lv, D. A Short Synthesis of Bisabolane Sesquiterpenes. Molecules 2011, 16, 8053-8061.

AMA Style

Du Z-T, Zheng S, Chen G, Lv D. A Short Synthesis of Bisabolane Sesquiterpenes. Molecules. 2011; 16(9):8053-8061.

Chicago/Turabian Style

Du, Zhen-Ting; Zheng, Shuai; Chen, Gang; Lv, Dong. 2011. "A Short Synthesis of Bisabolane Sesquiterpenes." Molecules 16, no. 9: 8053-8061.


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