Next Article in Journal
Effects of St John's Wort (Hypericum perforatum L.) Extracts on Epileptogenesis
Next Article in Special Issue
Antiphytoviral Activity of Sesquiterpene-Rich Essential Oils from Four Croatian Teucrium Species
Previous Article in Journal
Intramolecular C-H···O Hydrogen Bonding in 1,4-Dihydropyridine Derivatives
Article Menu

Article Versions

Export Article

Open AccessArticle
Molecules 2011, 16(9), 8053-8061; doi:10.3390/molecules16098053

A Short Synthesis of Bisabolane Sesquiterpenes

1
College of Science, Northwest A&F University, Yangling, Shaanxi 712100, China
2
Key Laboratory of Protection and Utilization of Biological Resources in Tarim Basin, Talimu University, Alaer, Xinjiang 843300, China
*
Author to whom correspondence should be addressed.
Received: 31 August 2011 / Revised: 4 September 2011 / Accepted: 14 September 2011 / Published: 19 September 2011
(This article belongs to the Special Issue Terpenoids)
Download PDF [436 KB, uploaded 18 June 2014]

Abstract

A facile total synthesis of three members of the bisabolane sesquiterpene family, namely (±)-curcumene, (±)-xanthorrhizol and (±)-curcuhydroquinone had been achieved in high overall yield. The synthesis used bromobenzene derivatives as starting materials. The halogen-lithium exchange followed by addition of isoprenylacetone and reduction of the obtained carbinols are the key steps of the synthetic pathway. This synthetic approach provides a new route to the bisabolane sesquiterpenes.
Keywords: curcumene; xanthorrhizol; curcuhydroquinone; synthesis curcumene; xanthorrhizol; curcuhydroquinone; synthesis
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Du, Z.-T.; Zheng, S.; Chen, G.; Lv, D. A Short Synthesis of Bisabolane Sesquiterpenes. Molecules 2011, 16, 8053-8061.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]

Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top