Molecules 2011, 16(9), 8053-8061; doi:10.3390/molecules16098053

A Short Synthesis of Bisabolane Sesquiterpenes

1,2,* email, 1email, 1email and 1email
Received: 31 August 2011; in revised form: 4 September 2011 / Accepted: 14 September 2011 / Published: 19 September 2011
(This article belongs to the Special Issue Terpenoids)
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: A facile total synthesis of three members of the bisabolane sesquiterpene family, namely (±)-curcumene, (±)-xanthorrhizol and (±)-curcuhydroquinone had been achieved in high overall yield. The synthesis used bromobenzene derivatives as starting materials. The halogen-lithium exchange followed by addition of isoprenylacetone and reduction of the obtained carbinols are the key steps of the synthetic pathway. This synthetic approach provides a new route to the bisabolane sesquiterpenes.
Keywords: curcumene; xanthorrhizol; curcuhydroquinone; synthesis
PDF Full-text Download PDF Full-Text [436 KB, uploaded 18 June 2014 19:40 CEST]

Export to BibTeX |

MDPI and ACS Style

Du, Z.-T.; Zheng, S.; Chen, G.; Lv, D. A Short Synthesis of Bisabolane Sesquiterpenes. Molecules 2011, 16, 8053-8061.

AMA Style

Du Z-T, Zheng S, Chen G, Lv D. A Short Synthesis of Bisabolane Sesquiterpenes. Molecules. 2011; 16(9):8053-8061.

Chicago/Turabian Style

Du, Zhen-Ting; Zheng, Shuai; Chen, Gang; Lv, Dong. 2011. "A Short Synthesis of Bisabolane Sesquiterpenes." Molecules 16, no. 9: 8053-8061.

Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert