A Short Synthesis of Bisabolane Sesquiterpenes
AbstractA facile total synthesis of three members of the bisabolane sesquiterpene family, namely (±)-curcumene, (±)-xanthorrhizol and (±)-curcuhydroquinone had been achieved in high overall yield. The synthesis used bromobenzene derivatives as starting materials. The halogen-lithium exchange followed by addition of isoprenylacetone and reduction of the obtained carbinols are the key steps of the synthetic pathway. This synthetic approach provides a new route to the bisabolane sesquiterpenes.
Share & Cite This Article
Du, Z.-T.; Zheng, S.; Chen, G.; Lv, D. A Short Synthesis of Bisabolane Sesquiterpenes. Molecules 2011, 16, 8053-8061.
Du Z-T, Zheng S, Chen G, Lv D. A Short Synthesis of Bisabolane Sesquiterpenes. Molecules. 2011; 16(9):8053-8061.Chicago/Turabian Style
Du, Zhen-Ting; Zheng, Shuai; Chen, Gang; Lv, Dong. 2011. "A Short Synthesis of Bisabolane Sesquiterpenes." Molecules 16, no. 9: 8053-8061.