Molecules 2011, 16(9), 8053-8061; doi:10.3390/molecules16098053
Article

A Short Synthesis of Bisabolane Sesquiterpenes

Zhen-Ting Du 1,2,* email, Shuai Zheng 1 email, Gang Chen 1 email and Dong Lv 1 email
1 College of Science, Northwest A&F University, Yangling, Shaanxi 712100, China 2 Key Laboratory of Protection and Utilization of Biological Resources in Tarim Basin, Talimu University, Alaer, Xinjiang 843300, China
* Author to whom correspondence should be addressed.
Received: 31 August 2011; in revised form: 4 September 2011 / Accepted: 14 September 2011 / Published: 19 September 2011
(This article belongs to the Special Issue Terpenoids)
PDF Full-text Download PDF Full-Text [436 KB, uploaded 19 September 2011 12:02 CEST]
Abstract: A facile total synthesis of three members of the bisabolane sesquiterpene family, namely (±)-curcumene, (±)-xanthorrhizol and (±)-curcuhydroquinone had been achieved in high overall yield. The synthesis used bromobenzene derivatives as starting materials. The halogen-lithium exchange followed by addition of isoprenylacetone and reduction of the obtained carbinols are the key steps of the synthetic pathway. This synthetic approach provides a new route to the bisabolane sesquiterpenes.
Keywords: curcumene; xanthorrhizol; curcuhydroquinone; synthesis

Article Statistics

Click here to load and display the download statistics.

Cite This Article

MDPI and ACS Style

Du, Z.-T.; Zheng, S.; Chen, G.; Lv, D. A Short Synthesis of Bisabolane Sesquiterpenes. Molecules 2011, 16, 8053-8061.

AMA Style

Du Z-T, Zheng S, Chen G, Lv D. A Short Synthesis of Bisabolane Sesquiterpenes. Molecules. 2011; 16(9):8053-8061.

Chicago/Turabian Style

Du, Zhen-Ting; Zheng, Shuai; Chen, Gang; Lv, Dong. 2011. "A Short Synthesis of Bisabolane Sesquiterpenes." Molecules 16, no. 9: 8053-8061.

Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert