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Molecules 2011, 16(11), 9207-9217; doi:10.3390/molecules16119207

Phenolic Compounds from Allium schoenoprasum, Tragopogon pratensis and Rumex acetosa and Their Antiproliferative Effects

1
Polymer Centre, Faculty of Technology, Tomas Bata University at Zlin, T.G.M. sq. 275, 762 72, Zlin, Czech Republic
2
Department of Food Technology and Microbiology, Faculty of Technology, Tomas Bata University at Zlin, T.G.M. sq. 275, 762 72 Zlin, Czech Republic
3
Centre for Polymer Systems, Polymer Centre, Tomas Bata University at Zlin, T.G.M. sq. 5555, 760 05 Zlin, Czech Republic
*
Author to whom correspondence should be addressed.
Received: 29 August 2011 / Revised: 21 October 2011 / Accepted: 26 October 2011 / Published: 3 November 2011
(This article belongs to the Section Medicinal Chemistry)
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Abstract

Experimental studies have shown that phenolic compounds have antiproliferative and tumour arresting effects. The aim of this original study was to investigate the content of phenolic compounds (PhC) in flowers of Allium schoenoprasum (chive), Tragopogon pratensis (meadow salsify) and Rumex acetosa (common sorrel) and their effect on proliferation of HaCaT cells. Antiproliferative effects were evaluated in vitro using the following concentrations of phenolic compounds in cultivation medium: 100, 75, 50 and 25 µg/mL. Phenolic composition was also determined by HPLC. The results indicate that even low concentrations of these flowers’ phenolic compounds inhibited cell proliferation significantly and the possible use of the studied herb’s flowers as sources of active phenolic compounds for human nutrition.
Keywords: Allium schoenoprasum; Tragopogon pratensis; Rumex acetosa; proliferation; phenolic compounds; HaCaT Allium schoenoprasum; Tragopogon pratensis; Rumex acetosa; proliferation; phenolic compounds; HaCaT
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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MDPI and ACS Style

Kucekova, Z.; Mlcek, J.; Humpolicek, P.; Rop, O.; Valasek, P.; Saha, P. Phenolic Compounds from Allium schoenoprasum, Tragopogon pratensis and Rumex acetosa and Their Antiproliferative Effects. Molecules 2011, 16, 9207-9217.

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