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Molecules 2010, 15(7), 4583-4588; doi:10.3390/molecules15074583

Alkaloids from Fissistigma latifolium (Dunal) Merr.

1, 2, 1, 2 and 1,*
1 Faculty of Applied Sciences, University Teknologi Mara, 40450 Shah Alam, Selangor, Malaysia 2 Department of Chemistry, Universiti Malaya, Kuala Lumpur, Malaysia
* Author to whom correspondence should be addressed.
Received: 1 June 2010 / Accepted: 7 June 2010 / Published: 24 June 2010
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A phytochemical study of the bark of Fissistigma latifolium (Annonaceae) yielded a new aporphine alkaloid, (-)-N-methylguattescidine (1), and eight known alkaloids: liriodenine (2), oxoxylopine (3), (-)-asimilobine (4), dimethyltryptamine (5), (-)-remerine (6), (-)-anonaine (7), columbamine (8) and lysicamine (9). The compounds were isolated using various chromatographic methods and structural elucidation was accomplished by means of spectroscopic methods, notably 1D-NMR (1H, 13C, DEPT), 2D-NMR (COSY, HMQC, HMBC), UV, IR and MS.
Keywords: Fissistigma latifolium; Annonaceae; alkaloids Fissistigma latifolium; Annonaceae; alkaloids
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Alias, A.; Hazni, H.; Mohd Jaafar, F.; Awang, K.; Hadiani Ismail, N. Alkaloids from Fissistigma latifolium (Dunal) Merr.. Molecules 2010, 15, 4583-4588.

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