Molecules 2010, 15(6), 3932-3957; doi:10.3390/molecules15063932
Article

Synthesis, Characterization and Biological Studies of Some Novel Thieno[2,3-d]pyrimidines

Received: 29 March 2010; in revised form: 20 May 2010 / Accepted: 27 May 2010 / Published: 1 June 2010
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: Several 2-unsubstituted thieno[2,3-d]pyrimidines have been prepared from 2-aminothiophene-3-carboxylic acid esters and their carbonitrile analogs. Some triazolo-thienopyrimidine and 2-thioxothienopyrimidine representatives have also been synthesized using thermal and microwave (MW) irradiation techniques. Structures of the prepared compounds were elucidated on the basis of IR, NMR, 2D NMR and mass spectral data. The biological activity of some selected synthesized compounds was also examined.
Keywords: thienopyridines; triazolothienopyrimidines; antibacterial activity; cytotoxic activity
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MDPI and ACS Style

Al-Taisan, K.M.; Al-Hazimi, H.M.A.; Al-Shihry, S.S. Synthesis, Characterization and Biological Studies of Some Novel Thieno[2,3-d]pyrimidines. Molecules 2010, 15, 3932-3957.

AMA Style

Al-Taisan KM, Al-Hazimi HMA, Al-Shihry SS. Synthesis, Characterization and Biological Studies of Some Novel Thieno[2,3-d]pyrimidines. Molecules. 2010; 15(6):3932-3957.

Chicago/Turabian Style

Al-Taisan, Khulud M.; Al-Hazimi, Hassan M. A.; Al-Shihry, Shar S. 2010. "Synthesis, Characterization and Biological Studies of Some Novel Thieno[2,3-d]pyrimidines." Molecules 15, no. 6: 3932-3957.

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