Molecules 2010, 15(6), 3932-3957; doi:10.3390/molecules15063932
Article

Synthesis, Characterization and Biological Studies of Some Novel Thieno[2,3-d]pyrimidines

1 Chemistry Department, College of Science, King Faisal University, P.O. Box 400, Hofuf 31982, Saudi Arabia 2 Chemistry Department, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia
* Author to whom correspondence should be addressed.
Received: 29 March 2010; in revised form: 20 May 2010 / Accepted: 27 May 2010 / Published: 1 June 2010
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Abstract: Several 2-unsubstituted thieno[2,3-d]pyrimidines have been prepared from 2-aminothiophene-3-carboxylic acid esters and their carbonitrile analogs. Some triazolo-thienopyrimidine and 2-thioxothienopyrimidine representatives have also been synthesized using thermal and microwave (MW) irradiation techniques. Structures of the prepared compounds were elucidated on the basis of IR, NMR, 2D NMR and mass spectral data. The biological activity of some selected synthesized compounds was also examined.
Keywords: thienopyridines; triazolothienopyrimidines; antibacterial activity; cytotoxic activity

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MDPI and ACS Style

Al-Taisan, K.M.; Al-Hazimi, H.M.A.; Al-Shihry, S.S. Synthesis, Characterization and Biological Studies of Some Novel Thieno[2,3-d]pyrimidines. Molecules 2010, 15, 3932-3957.

AMA Style

Al-Taisan KM, Al-Hazimi HMA, Al-Shihry SS. Synthesis, Characterization and Biological Studies of Some Novel Thieno[2,3-d]pyrimidines. Molecules. 2010; 15(6):3932-3957.

Chicago/Turabian Style

Al-Taisan, Khulud M.; Al-Hazimi, Hassan M. A.; Al-Shihry, Shar S. 2010. "Synthesis, Characterization and Biological Studies of Some Novel Thieno[2,3-d]pyrimidines." Molecules 15, no. 6: 3932-3957.

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