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Bacterial Extracellular Polysaccharides Involved in Biofilm Formation
Faculty of Life and Social Sciences Swinburne University of Technology, PO Box 218, Hawthorn, Victoria 3122, Australia
CSIRO Minerals, Bayview Avenue, Clayton, Victoria 3168, Australia
* Author to whom correspondence should be addressed.
Received: 18 May 2009; in revised form: 26 June 2009 / Accepted: 1 July 2009 / Published: 13 July 2009
Abstract: Extracellular polymeric substances (EPS) produced by microorganisms are a complex mixture of biopolymers primarily consisting of polysaccharides, as well as proteins, nucleic acids, lipids and humic substances. EPS make up the intercellular space of microbial aggregates and form the structure and architecture of the biofilm matrix. The key functions of EPS comprise the mediation of the initial attachment of cells to different substrata and protection against environmental stress and dehydration. The aim of this review is to present a summary of the current status of the research into the role of EPS in bacterial attachment followed by biofilm formation. The latter has a profound impact on an array of biomedical, biotechnology and industrial fields including pharmaceutical and surgical applications, food engineering, bioremediation and biohydrometallurgy. The diverse structural variations of EPS produced by bacteria of different taxonomic lineages, together with examples of biotechnological applications, are discussed. Finally, a range of novel techniques that can be used in studies involving biofilm-specific polysaccharides is discussed.
Keywords: extracellular polymeric substances; biofilms; bioremediation; acidithiobacillus ferrooxidans
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MDPI and ACS Style
Vu, B.; Chen, M.; Crawford, R.J.; Ivanova, E.P. Bacterial Extracellular Polysaccharides Involved in Biofilm Formation. Molecules 2009, 14, 2535-2554.
Vu B, Chen M, Crawford RJ, Ivanova EP. Bacterial Extracellular Polysaccharides Involved in Biofilm Formation. Molecules. 2009; 14(7):2535-2554.
Vu, Barbara; Chen, Miao; Crawford, Russell J.; Ivanova, Elena P. 2009. "Bacterial Extracellular Polysaccharides Involved in Biofilm Formation." Molecules 14, no. 7: 2535-2554.