Molecules 2009, 14(4), 1595-1604; doi:10.3390/molecules14041595
Article

Synthesis of γ-Nitro Aliphatic Methyl Esters Via Michael Additions Promoted by Microwave Irradiation

Centro de Investigaciones Químicas, Universidad Autónoma del Estado de Morelos. Av. Universidad No. 1001, Col. Chamilpa, C.P. 62210 Cuernavaca, Mor., Mexico
* Author to whom correspondence should be addressed.
Received: 5 February 2009; in revised form: 21 March 2009 / Accepted: 8 April 2009 / Published: 21 April 2009
(This article belongs to the Special Issue Microwave Assisted Synthesis)
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Abstract: A simple and efficient protocol has been developed for the direct synthesis of γ-nitrobutyric acid methyl esters under microwave irradiation. This methodology reduces reaction times from days to minutes, compared to conventional conditions. Additionally, these conditions increased yields and provided cleaner reactions.
Keywords: Microwave irradiation; α; β-Unsaturated; Michael additions; γ-Nitro aliphatic methyl esters; Catalysis

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MDPI and ACS Style

Escalante, J.; Díaz-Coutiño, F.D. Synthesis of γ-Nitro Aliphatic Methyl Esters Via Michael Additions Promoted by Microwave Irradiation. Molecules 2009, 14, 1595-1604.

AMA Style

Escalante J, Díaz-Coutiño FD. Synthesis of γ-Nitro Aliphatic Methyl Esters Via Michael Additions Promoted by Microwave Irradiation. Molecules. 2009; 14(4):1595-1604.

Chicago/Turabian Style

Escalante, Jaime; Díaz-Coutiño, Francisco D. 2009. "Synthesis of γ-Nitro Aliphatic Methyl Esters Via Michael Additions Promoted by Microwave Irradiation." Molecules 14, no. 4: 1595-1604.

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