Molecules 2009, 14(12), 5247-5280; doi:10.3390/molecules14125247
Article

1-Arylsulfonyl-2-(Pyridylmethylsulfinyl) Benzimidazoles as New Proton Pump Inhibitor Prodrugs

1,* email, 1,* email, 1email and 2email
Received: 9 October 2009; in revised form: 8 December 2009 / Accepted: 14 December 2009 / Published: 15 December 2009
(This article belongs to the collection Prodrugs)
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: New arylsulfonyl proton pump inhibitor (PPI) prodrug forms were synthesized. These prodrugs provided longer residence time of an effective PPI plasma concentration, resulting in better gastric acid inhibition.
Keywords: proton pump inhibitor; prodrug; gastric acid secretion
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MDPI and ACS Style

Shin, J.M.; Sachs, G.; Cho, Y.-M.; Garst, M. 1-Arylsulfonyl-2-(Pyridylmethylsulfinyl) Benzimidazoles as New Proton Pump Inhibitor Prodrugs. Molecules 2009, 14, 5247-5280.

AMA Style

Shin JM, Sachs G, Cho Y-M, Garst M. 1-Arylsulfonyl-2-(Pyridylmethylsulfinyl) Benzimidazoles as New Proton Pump Inhibitor Prodrugs. Molecules. 2009; 14(12):5247-5280.

Chicago/Turabian Style

Shin, Jai Moo; Sachs, George; Cho, Young-moon; Garst, Michael. 2009. "1-Arylsulfonyl-2-(Pyridylmethylsulfinyl) Benzimidazoles as New Proton Pump Inhibitor Prodrugs." Molecules 14, no. 12: 5247-5280.

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