Synthetic Approaches and Biological Activities of 4-Hydroxycoumarin Derivatives

doi:10.3390/molecules14114790

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Molecules 2009, 14(11), 4790-4803; doi:10.3390/molecules14114790

Review

Synthetic Approaches and Biological Activities of 4-Hydroxycoumarin Derivatives

Jae-Chul Jung¹ and Oee-Sook Park^2,*

¹ Ewha Global Challenge, BK21 and Medical Research Institute, School of Medicine, Ewha Womans University, Seoul 158–710, Korea ² Department of Chemistry, Institute for Basic Sciences, College of Natural Sciences, Chungbuk National University, Cheongju 361–763, Chungbuk, Korea

* Author to whom correspondence should be addressed.

Received: 19 October 2009; in revised form: 16 November 2009 / Accepted: 18 November 2009 / Published: 23 November 2009

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Abstract: The main purpose of this review is to summarize recent chemical syntheses and structural modifications of 4-hydroxycoumarin and its derivatives, of interest due to their characteristic conjugated molecular architecture and biological activities.

Keywords: 4-hydroxycoumarin; anticoagulant; rodenticide; ring cyclization; tetralone; coupling reaction

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MDPI and ACS Style

Jung, J.-C.; Park, O.-S. Synthetic Approaches and Biological Activities of 4-Hydroxycoumarin Derivatives. Molecules 2009, 14, 4790-4803.

AMA Style

Jung J-C, Park O-S. Synthetic Approaches and Biological Activities of 4-Hydroxycoumarin Derivatives. Molecules. 2009; 14(11):4790-4803.

Chicago/Turabian Style

Jung, Jae-Chul; Park, Oee-Sook. 2009. "Synthetic Approaches and Biological Activities of 4-Hydroxycoumarin Derivatives." Molecules 14, no. 11: 4790-4803.

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