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Molecules 2009, 14(12), 4804-4813; doi:10.3390/molecules14124804
Article

New Cucurbitane Triterpenoids and Steroidal Glycoside from Momordica charantia

,
,
 and *
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Science, Kunming 650204 Yunnan, China
* Author to whom correspondence should be addressed.
Received: 26 October 2009 / Revised: 9 November 2009 / Accepted: 11 November 2009 / Published: 25 November 2009
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Abstract

Three new cucurbitane triterpenoids 1–3 and one new steroidal glycoside 4, were isolated together with ten known compounds from Momordica charantia. The structures of new compounds were determined to be 19(R)-n-butanoxy-5β,19-epoxycucurbita-6,23-diene-3β,25-diol 3-O-β-glucopyranoside (1), 23-O-β-allopyranosylecucurbita-5,24-dien-7α,3β,22(R),23(S)-tetraol 3-O-β-allopyranoside. (2), 23(R),24(S),25-trihydroxycucurbit-5-ene 3-O-{[β-glucopyranosyl(1→6)]-O-β-glucopyranosyl}-25-O-β-glucopyranoside (3), and 24(R)-stigmastan-3β,5α,6β-triol-25-ene 3-O-β-glucopyranoside (4), respectively. Their structures were elucidated by the combination of mass spectrometry (MS), one and two-dimensional NMR experiments and chemical reactions.
Keywords: Momordica charantia; cucurbitane triterpenoids; steroidal glycoside; cucurbitaceae Momordica charantia; cucurbitane triterpenoids; steroidal glycoside; cucurbitaceae
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Liu, J.-Q.; Chen, J.-C.; Wang, C.-F.; Qiu, M.-H. New Cucurbitane Triterpenoids and Steroidal Glycoside from Momordica charantia. Molecules 2009, 14, 4804-4813.

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