Molecules 2009, 14(12), 4804-4813; doi:10.3390/molecules14124804
Article

New Cucurbitane Triterpenoids and Steroidal Glycoside from Momordica charantia

Jie-Qing Liuemail, Jian-Chao Chenemail, Cui-Fang Wangemail and Ming-Hua Qiu* email
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Science, Kunming 650204 Yunnan, China
* Author to whom correspondence should be addressed.
Received: 26 October 2009; in revised form: 9 November 2009 / Accepted: 11 November 2009 / Published: 25 November 2009
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Abstract: Three new cucurbitane triterpenoids 1–3 and one new steroidal glycoside 4, were isolated together with ten known compounds from Momordica charantia. The structures of new compounds were determined to be 19(R)-n-butanoxy-5β,19-epoxycucurbita-6,23-diene-3β,25-diol 3-O-β-glucopyranoside (1), 23-O-β-allopyranosylecucurbita-5,24-dien-7α,3β,22(R),23(S)-tetraol 3-O-β-allopyranoside. (2), 23(R),24(S),25-trihydroxycucurbit-5-ene 3-O-{[β-glucopyranosyl(1→6)]-O-β-glucopyranosyl}-25-O-β-glucopyranoside (3), and 24(R)-stigmastan-3β,5α,6β-triol-25-ene 3-O-β-glucopyranoside (4), respectively. Their structures were elucidated by the combination of mass spectrometry (MS), one and two-dimensional NMR experiments and chemical reactions.
Keywords: Momordica charantia; cucurbitane triterpenoids; steroidal glycoside; cucurbitaceae

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Cite This Article

MDPI and ACS Style

Liu, J.-Q.; Chen, J.-C.; Wang, C.-F.; Qiu, M.-H. New Cucurbitane Triterpenoids and Steroidal Glycoside from Momordica charantia. Molecules 2009, 14, 4804-4813.

AMA Style

Liu J-Q, Chen J-C, Wang C-F, Qiu M-H. New Cucurbitane Triterpenoids and Steroidal Glycoside from Momordica charantia. Molecules. 2009; 14(12):4804-4813.

Chicago/Turabian Style

Liu, Jie-Qing; Chen, Jian-Chao; Wang, Cui-Fang; Qiu, Ming-Hua. 2009. "New Cucurbitane Triterpenoids and Steroidal Glycoside from Momordica charantia." Molecules 14, no. 12: 4804-4813.

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