Molecules 2009, 14(11), 4440-4453; doi:10.3390/molecules14114440
Article

The Effect of Long-Running Severe Selenium-Deficiency on the Amount of Iron and Zinc in the Organs of Rats

1,2email, 1, 1, 1, 1, 1 and 1,* email
Received: 5 October 2009; in revised form: 2 November 2009 / Accepted: 4 November 2009 / Published: 5 November 2009
(This article belongs to the Special Issue Selenium and Tellurium Chemistry)
Download PDF [275 KB, uploaded 18 June 2014]
Abstract: The amounts of selenium (Se), iron (Fe), and zinc (Zn) in the liver, kidney, and spleen as a function of age of rats measured using instrumental neutron activation analysis were compared between Se-deficient (SeD) rats and normal rats. The SeD model rats can live for more than 50 weeks. The effect of Se-deficinecy in rats might be weak, compared to the marked malfunction of GSH-Px. The SeD rats can be considered as a model of nonlethal chronic oxidative stress. Fluctuations of Fe and Zn in the liver of Se-deficient rats were observed. The amount of redox-relating minerals, such as Fe and Zn, in SeD rat organs is changeable depending on the age.
Keywords: instrumental neutron activation analysis; bio-trace element; mineral; aging; oxidative stress
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Export to BibTeX |
EndNote


MDPI and ACS Style

Matsumoto, K.-I.; Terada, S.; Ariyoshi, M.; Okajo, A.; Hisamatsu, A.; Ui, I.; Endo, K. The Effect of Long-Running Severe Selenium-Deficiency on the Amount of Iron and Zinc in the Organs of Rats. Molecules 2009, 14, 4440-4453.

AMA Style

Matsumoto K-I, Terada S, Ariyoshi M, Okajo A, Hisamatsu A, Ui I, Endo K. The Effect of Long-Running Severe Selenium-Deficiency on the Amount of Iron and Zinc in the Organs of Rats. Molecules. 2009; 14(11):4440-4453.

Chicago/Turabian Style

Matsumoto, Ken-ichiro; Terada, Sachiyo; Ariyoshi, Marie; Okajo, Aya; Hisamatsu, Atsushi; Ui, Iori; Endo, Kazutoyo. 2009. "The Effect of Long-Running Severe Selenium-Deficiency on the Amount of Iron and Zinc in the Organs of Rats." Molecules 14, no. 11: 4440-4453.


Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert