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Chemical Constituents from Clematis delavayi var. spinescens
Laboratory of Ethnobotany, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, China
Institute of Tibetan Plateau Research at Kunming, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, Yunnan, China
Biology Institute of Shandong Academy of Sciences, Jinan 250014, Shandong, China
* Authors to whom correspondence should be addressed.
Received: 20 October 2009; in revised form: 29 October 2009 / Accepted: 30 October 2009 / Published: 5 November 2009
Abstract: A new coumarin, 7-hydroxy-4,6-dimethoxy-5-methylcoumarin (1), was isolated from the aerial parts of Clematis delavayi var. spinescens together with 17 known compounds. Their structures were identified by extensive spectral analysis, especially 2D NMR techniques. Antiangiogenic effects of all compounds were evaluated using a zebrafish model.
Keywords: coumarin; Clematis delavayi var. spinescens; NMR; antiangiogenic effects
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Li, Y.; Wang, S.-F.; Zhao, Y.-L.; Liu, K.-C.; Wang, X.-M.; Yang, Y.-P.; Li, X.-L. Chemical Constituents from Clematis delavayi var. spinescens. Molecules 2009, 14, 4433-4439.
Li Y, Wang S-F, Zhao Y-L, Liu K-C, Wang X-M, Yang Y-P, Li X-L. Chemical Constituents from Clematis delavayi var. spinescens. Molecules. 2009; 14(11):4433-4439.
Li, Yang; Wang, Si-Feng; Zhao, Yan-Li; Liu, Ke-Chun; Wang, Xi-Min; Yang, Yong-Ping; Li, Xiao-Li. 2009. "Chemical Constituents from Clematis delavayi var. spinescens." Molecules 14, no. 11: 4433-4439.