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Molecules 2008, 13(8), 1712-1721; doi:10.3390/molecules13081712

New Triterpene Diglycosides from the Rhizome of Cimifuga foetida

1, 1,2, 1,2, 1, 3 and 1,2,*
1 State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, the Chinese Academy of Sciences, Kunming, 650204, P. R. China 2 Graduate School of the Chinese Academy of Sciences, Beijing, 100039, P. R. China 3 Program for Collaborative Research in the Pharmaceutical Sciences, (m/c877), Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, the University of Illinois at Chicago, 833 S. Wood St., Chicago, IL 60612, USA
* Author to whom correspondence should be addressed.
Received: 17 May 2008 / Revised: 17 July 2008 / Accepted: 18 July 2008 / Published: 13 August 2008
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Five new 9,19-cycloartane triterpene diglycosides, which have been named cimiaceroside C (1), and cimifosides A-D (2-5) together with the known compounds cimiracemoside D (6), cimidahurine (7) and α-D-glucopyranosyl-l-β-D-fructofuranoside (8) were isolated from the rhizome of Cimicifuga foetida. The new triterpene diglycosides 1-5 were identified as cimiacerol-3-O-β-D-xylopyranosyl-(1''→3')-β-D-xylopyranoside, 12β-hydroxycimigenol-3-O-β-D-xylopyranosyl-(1''→3')-β-D-xylopyranoside, 25-Oacetylcimig- enol-3-O-β-D-xylopyranosyl-(1''→3')-β-D-xylopyranoside, 24- acetylhydroshengmanol-3-O-β-D-xylopyranosyl-(1''→3')-β-D-xylopyranoside and 26- deoxyacetylacteol-3-O-β-D-xylo- pyranosyl-(1''→3')-β-D-xylopyranoside, respectively, based on analysis of their spectral data and chemical reactions.
Keywords: Cimicifuga foetida; Cycloartane Triterpenoid; Diglycosides; Cimifosides. Cimicifuga foetida; Cycloartane Triterpenoid; Diglycosides; Cimifosides.
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Sun, L.; Yan, J.; Nian, Y.; Zhou, L.; Zhang, H.; Qiu, M. New Triterpene Diglycosides from the Rhizome of Cimifuga foetida. Molecules 2008, 13, 1712-1721.

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