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Molecules 2008, 13(8), 1712-1721; doi:10.3390/molecules13081712

New Triterpene Diglycosides from the Rhizome of Cimifuga foetida

1, 1,2, 1,2, 1, 3 and 1,2,*
1 State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, the Chinese Academy of Sciences, Kunming, 650204, P. R. China 2 Graduate School of the Chinese Academy of Sciences, Beijing, 100039, P. R. China 3 Program for Collaborative Research in the Pharmaceutical Sciences, (m/c877), Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, the University of Illinois at Chicago, 833 S. Wood St., Chicago, IL 60612, USA
* Author to whom correspondence should be addressed.
Received: 17 May 2008 / Revised: 17 July 2008 / Accepted: 18 July 2008 / Published: 13 August 2008
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Five new 9,19-cycloartane triterpene diglycosides, which have been named cimiaceroside C (1), and cimifosides A-D (2-5) together with the known compounds cimiracemoside D (6), cimidahurine (7) and α-D-glucopyranosyl-l-β-D-fructofuranoside (8) were isolated from the rhizome of Cimicifuga foetida. The new triterpene diglycosides 1-5 were identified as cimiacerol-3-O-β-D-xylopyranosyl-(1''→3')-β-D-xylopyranoside, 12β-hydroxycimigenol-3-O-β-D-xylopyranosyl-(1''→3')-β-D-xylopyranoside, 25-Oacetylcimig- enol-3-O-β-D-xylopyranosyl-(1''→3')-β-D-xylopyranoside, 24- acetylhydroshengmanol-3-O-β-D-xylopyranosyl-(1''→3')-β-D-xylopyranoside and 26- deoxyacetylacteol-3-O-β-D-xylo- pyranosyl-(1''→3')-β-D-xylopyranoside, respectively, based on analysis of their spectral data and chemical reactions.
Keywords: Cimicifuga foetida; Cycloartane Triterpenoid; Diglycosides; Cimifosides. Cimicifuga foetida; Cycloartane Triterpenoid; Diglycosides; Cimifosides.
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Sun, L.; Yan, J.; Nian, Y.; Zhou, L.; Zhang, H.; Qiu, M. New Triterpene Diglycosides from the Rhizome of Cimifuga foetida. Molecules 2008, 13, 1712-1721.

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