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Molecules 2008, 13(7), 1465-1471; doi:10.3390/molecules13071465

Simplexidine, a 4-Alkylpyridinium Alkaloid from the Caribbean Sponge Plakortis simplex

Dipartimento di Chimica delle Sostanze Naturali, Università di Napoli “Federico II”, Via D. Montesano 49, 80131 Napoli, Italy
Author to whom correspondence should be addressed.
Received: 25 June 2008 / Accepted: 16 July 2008 / Published: 17 July 2008
(This article belongs to the Special Issue Alkaloids: Novel Therapeutic Perspectives)
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Chemical analysis of the secondary metabolites of the Caribbean sponge Plakortis simplex, a source of many bioactive compounds, showed the presence of the new metabolite simplexidine (4), belonging to the extremely rare class of 4-alkyl-pyridinium alkaloids. The structural characterization of this molecule, based on spectroscopic methods, is reported.
Keywords: Simplexidin; alkaloids; pyridinium; Plakortis; NMR. Simplexidin; alkaloids; pyridinium; Plakortis; NMR.
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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MDPI and ACS Style

Fattorusso, E.; Romano, A.; Scala, F.; Taglialatela-Scafati, O. Simplexidine, a 4-Alkylpyridinium Alkaloid from the Caribbean Sponge Plakortis simplex. Molecules 2008, 13, 1465-1471.

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