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Molecules 2008, 13(7), 1465-1471; doi:10.3390/molecules13071465
Article

Simplexidine, a 4-Alkylpyridinium Alkaloid from the Caribbean Sponge Plakortis simplex

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Received: 25 June 2008 / Accepted: 16 July 2008 / Published: 17 July 2008
(This article belongs to the Special Issue Alkaloids: Novel Therapeutic Perspectives)
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Abstract

Chemical analysis of the secondary metabolites of the Caribbean sponge Plakortis simplex, a source of many bioactive compounds, showed the presence of the new metabolite simplexidine (4), belonging to the extremely rare class of 4-alkyl-pyridinium alkaloids. The structural characterization of this molecule, based on spectroscopic methods, is reported.
Keywords: Simplexidin; alkaloids; pyridinium; Plakortis; NMR. Simplexidin; alkaloids; pyridinium; Plakortis; NMR.
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Fattorusso, E.; Romano, A.; Scala, F.; Taglialatela-Scafati, O. Simplexidine, a 4-Alkylpyridinium Alkaloid from the Caribbean Sponge Plakortis simplex. Molecules 2008, 13, 1465-1471.

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