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Molecules 2008, 13(10), 2482-2487; doi:10.3390/molecules13102482

Variation of Ursolic Acid Content in Eight Ocimum Species from Northeastern Brazil

1,* , 2,3, 3, 4, 1, 1 and 2
1 Departamento de Química Analítica e Fisico-Química - Departamento de Química Orgânica e Inorgânica, Universidade Federal do Ceará, 60.455-970, Fortaleza, CE, Brazil 2 Laboratório de Química de Produtos Naturais, Universidade Estadual do Ceará, Campus do Itaperí, CEP 60.740-000, Fortaleza, CE, Brazil 3 Parque de Desenvolvimento Tecnológico (PADETEC), 60455-970, Fortaleza, CE, Brazil 4 Universidade de Fortaleza, 60811-905, Fortaleza, CE, Brazil
* Author to whom correspondence should be addressed.
Received: 27 June 2008 / Revised: 16 September 2008 / Accepted: 16 September 2008 / Published: 14 October 2008
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Ursolic acid is a very important compound due to its biological potential as an anti-inflammatory, trypanocidal, antirheumatic, antiviral, antioxidant and antitumoral agent. This study presents the HPLC analysis of ursolic acid (UA) content in eight different Ocimum species: O. americanum L., O. basilicum L, O. basilicum var purpurascens Benth, O. basilicum var. minimum L, O. gratissimum L, O. micranthum Willd, O. selloi Benth. and O. tenuiflorum L. grown in Northeastern Brazil. In these Ocimum species, UA was detected in different yields, with O. tenuiflorum showing the highest content (2.02%). This yield is very significant when compared with other sources of UA.
Keywords: Labiatae; Ursolic acid; Ocimum; HPLC Labiatae; Ursolic acid; Ocimum; HPLC
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Silva, M.G.V.; Vieira, I.G.P.; Mendes, F.N.P.; Albuquerque, I.L.; Dos Santos, R.N.; Silva, F.O.; Morais, S.M. Variation of Ursolic Acid Content in Eight Ocimum Species from Northeastern Brazil. Molecules 2008, 13, 2482-2487.

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