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Molecules 1997, 2(12), 186-232; doi:10.3390/21200186
Article

Preparation of α,β-Unsaturated Ketones Bearing a Trifluoromethyl Group and Their Application in Organic Synthesis

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Received: 9 December 1996 / Accepted: 28 March 1997 / Published: 1 December 1997
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Abstract

The approaches to the synthesis of α,β-unsaturated CF3-containing ketones and their use in organic chemistry are reviewed. The synthetic applications of these ketones are discussed. The formation of 4-, 5-, 6- and 7-membered heterocycles bearing a CF3 group based on reactions of α,β-unsaturated CF3-containing ketones with different nucleophiles are discussed.
Keywords: α; β-Unsaturated trifluoromethyl ketones; CF3-containing heterocycles; trifluoroacetylation; synthesis; review α; β-Unsaturated trifluoromethyl ketones; CF3-containing heterocycles; trifluoroacetylation; synthesis; review
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Nenajdenko, V.G.; Sanin, A.V.; Balenkova, E.S. Preparation of α,β-Unsaturated Ketones Bearing a Trifluoromethyl Group and Their Application in Organic Synthesis. Molecules 1997, 2, 186-232.

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