**5. Conclusions**

We successfully constructed the lentiviral miR-143 overexpression vector and transfected it into human mast cell. In this study, we also identified IL-13Rα1 as a target gene of miR-143, and that it was inhibited by overexpression of miR-143 in mast cells. All these findings indicate that miR-143 may play important roles in triggering allergic inflammation.
