Reprint

The Multi-Dimensional Contributions of Prefrontal Circuits to Emotion Regulation during Adulthood and Critical Stages of Development

Edited by
November 2019
188 pages
  • ISBN978-3-03921-702-1 (Paperback)
  • ISBN978-3-03921-703-8 (PDF)

This is a Reprint of the Special Issue The Multi-Dimensional Contributions of Prefrontal Circuits to Emotion Regulation during Adulthood and Critical Stages of Development that was published in

Biology & Life Sciences
Computer Science & Mathematics
Medicine & Pharmacology
Public Health & Healthcare
Summary

The prefrontal cortex (PFC) plays a pivotal role in regulating our emotions. The importance of ventromedial regions in emotion regulation, including the ventral sector of the medial PFC, the medial sector of the orbital cortex and subgenual cingulate cortex, have been recognized for a long time. However, it is increasingly apparent that lateral and dorsal regions of the PFC, as well as neighbouring dorsal anterior cingulate cortex, also play a role. Defining the underlying psychological mechanisms by which these functionally distinct regions modulate emotions and the nature and extent of their interactions is a critical step towards better stratification of the symptoms of mood and anxiety disorders. It is also important to extend our understanding of these prefrontal circuits in development. Specifically, it is important to determine whether they exhibit differential sensitivity to perturbations by known risk factors such as stress and inflammation at distinct developmental epochs. This Special Issue brings together the most recent research in humans and other animals that addresses these important issues, and in doing so, highlights the value of the translational approach.

Format
  • Paperback
License and Copyright
© 2020 by the authors; CC BY license
Keywords
Williams Syndrome; neuron density; glia density; ventromedial prefrontal cortex; prelimbic; infralimbic; medial prefrontal cortex; cognitive control; hierarchical control; occasion setting; extinction; Pavlovian; fear extinction; adolescence; prefrontal cortex; amygdala; triadic neural systems model; development; adolescence; machine learning; networks; anxiety; depression; adolescence; emotion regulation; fMRI; psychophysiology; psychological treatment; reliability; functional magnetic resonance imaging (fMRI); connectivity; emotion processing; amygdala; prefrontal cortex; depression; adolescent; prefrontal cortex; neural; reward; positive and negative; prefrontal cortex; stress adolescence; aging; calcium; cAMP; dopamine; norepinephrine; serotonin transporter; rat; fear extinction; medial prefrontal cortex; NMDA; BDNF; adolescence; age; area 25; infralimbic; autonomic; emotion; anhedonia; negative affect; anticipatory arousal