Reprint
Model-Based Tools for Pharmaceutical Manufacturing Processes
Edited by
March 2020
188 pages
- ISBN978-3-03928-424-5 (Paperback)
- ISBN978-3-03928-425-2 (PDF)
This book is a reprint of the Special Issue Model-Based Tools for Pharmaceutical Manufacturing Processes that was published in
Biology & Life Sciences
Chemistry & Materials Science
Computer Science & Mathematics
Engineering
Environmental & Earth Sciences
Summary
The Special Issue on “Model-Based Tools for Pharmaceutical Manufacturing Processes” will curate novel advances in the development and application of model-based tools to address ever-present challenges of the traditional pharmaceutical manufacturing practice as well as new trends. This book provides a collection of nine papers on original advances in the model-based process unit, system-level, quality-by-design under uncertainty, and decision-making applications of pharmaceutical manufacturing processes.
Format
- Paperback
License
© 2020 by the authors; CC BY-NC-ND license
Keywords
pharmaceutical processes; flexibility analysis; probabilistic design space; global optimization; model integration; flowsheet modeling; sensitivity analysis; continuous manufacturing; wet granulation; Amoxicillin; enzymatic synthesis; non-isothermal modelling; parameter estimation; dynamic optimisation; enzymatic reaction; reversible reaction; dynamic modelling; pyrimidine-nucleoside phosphorylase; spectroscopic assay; process kinetics; ODE model; process design; single-use technology; parenteral manufacturing; MATLAB Production Server; software development; multi-objective decision-making; robust process design; batch-to-batch variation; parametric probability-box; point estimate method; pharmaceutical manufacturing; freeze-drying; quality by design; pharmaceutical manufacturing; polynomial chaos; global sensitivity analysis; spray drying; process modeling; return on investment; diffusion of innovation; residence time distribution; continuous stirred tank reactor; bypassing; Fourier analysis; continuous manufacturing; n/a