Reprint
Targeting Wnt Signaling in Cancer: Opportunities Abound If We Can Avoid the Sword of Damocles
Edited by
March 2022
298 pages
- ISBN978-3-0365-3517-3 (Hardback)
- ISBN978-3-0365-3518-0 (PDF)
This book is a reprint of the Special Issue Targeting Wnt Signaling in Cancer: Opportunities Abound If We Can Avoid the Sword of Damocles that was published in
Biology & Life Sciences
Medicine & Pharmacology
Summary
Dysregulation of Wnt signaling is known to be associated with various cancers. As such, identification of novel Wnt pathway targets in cancer and better characterization of already-known targets present exciting, emerging opportunities for cancer treatment. In this Special Issue, we feature papers which discuss the role of Wnt signaling and associated targets in cancer metabolism, tumor immune response, and tumor microenvironment. Papers discussing a range of Wnt-mediated cancers, including those of the colon, liver, pancreas, synovium, bladder, etc., are included.
Format
- Hardback
License
© 2022 by the authors; CC BY-NC-ND license
Keywords
Wnt signaling; synovial sarcoma; TNIK; NCB-0846; MYC; Wnt signaling; hepatitis B virus; HBV; cancer; liver cancer; β-catenin; TCF/LEF; pancreatic cancer; pancreatic stellate cells; Wnt signaling; CBP; p300; pancreatitis; fibrosis; Wnt signaling; just-right signaling; APC; β-catenin; colorectal cancer; RNA-binding proteins; Musashi; drug discovery; Notch signaling; Wnt signaling; cancer therapy; fungi secondary metabolite derivative; microenvironment; Wnt; AML; drug target; Wnt; signaling; colorectal; cancer; porcupine; R-spondin; serrated; immunotherapy; wnt; β-catenin; vitamin D; cancer; colon cancer; L1; Wnt target genes; β-catenin; cell adhesion; colon cancer; NF-κB; invasion and metastasis; cancer stem cells; EMT; Lgr5; colorectal cancer; Wnt/beta-catenin signaling; angiogenesis; anti-angiogenic therapy; Wnt signaling; β-catenin; cancer; gastrointestinal cancers; therapeutic targeting of Wnt signaling; β-catenin paradox; molecular targeting; Wnt; β-catenin; urothelial cancer; immune checkpoint inhibitor; immunotherapy resistance; CBP; p300; IBD; colitis; colorectal cancer; Wnt; β-catenin mutations; tumor metabolism; tumor immunology; molecular therapeutics; precision medicine; astrocytic brain tumors; Wnt signaling; DKKs; GSK3β; APC; β-catenin