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Vaccines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Novel Insights and Advances in Aquatic Vaccines

edited by

Erlong Wang

, Tao Liu and

Yibin Yang

submission deadline 12 Jul 2025 | 1 articles | Viewed by 2398 | Submission Open

Keywords: aquatic vaccines; polyvalent vaccines; combination vaccines; adjuvant vaccines; vaccination routes; immersion vaccines

(This special issue belongs to the Section Veterinary Vaccines)

Antiviral T and B Cell Immunity

edited by Constantinos Petrovas, Ashish Arunkumar Sharma and Susan Pereira Ribeiro

submission deadline 15 Jul 2025 | 5 articles | Viewed by 8473 | Submission Open

Keywords: virus; adaptive immunity; pathogenesis; vaccines

(This special issue belongs to the Section Vaccines, Clinical Advancement, and Associated Immunology)

The Current Situation and Future Perspectives of Vaccines against Infectious Diseases in Children and Women—2nd Edition

edited by

Masatoki Kaneko

submission deadline 20 Jul 2025 | 1 articles | Viewed by 2058 | Submission Open

Keywords: children; mother-to-child transmission; pregnant women; women; vaccine

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Measles Outbreak: Causes and Vaccination Strategies to Overcome

edited by

Cristiana Ferrari

and

Nicolas Vignier

submission deadline 20 Jul 2025 | Viewed by 564 | Submission Open

Keywords: measles outbreak; vaccine hesitancy; immunization strategies; public health policy; herd immunity; disease prevention; vaccination coverage

(This special issue belongs to the Section Vaccines and Public Health)

The Role of Vaccination on Vaccine Preventable Foodborne Disease

edited by

Cecilia Trucchi

and

Vincenzo Restivo

submission deadline 25 Jul 2025 | Viewed by 710 | Submission Open

Keywords: foodborne pathogens; foodborne illnesses; food safety; food contamination; food chain; vaccines

(This special issue belongs to the Section Epidemiology and Vaccination)

Diagnosis and Control of African Swine Fever Virus (ASFV) Infection

edited by Marisa Arias and Carmina Gallardo

submission deadline 31 Jul 2025 | 9 articles | Viewed by 28098 | Submission Open

Keywords: African swine fever; ASF V transmission; ASFV infection dynamic; ASF diagnosis; ASF pathology; ASF control strategies; ASF alternative samples for diagnosis; ASF DIVA test; ASF vaccines

(This special issue belongs to the Section Veterinary Vaccines)

Understanding Immune Responses to COVID-19 Vaccines

edited by

Federico De Marco

submission deadline 31 Jul 2025 | 10 articles | Viewed by 21796 | Submission Open

Keywords: variants and the short duration of protective immunity; immune responses; COVID-19 vaccines

(This special issue belongs to the Section COVID-19 Vaccines and Vaccination)

Interplay between Host and Pathogen: Effects of Infection and Immune Responses

edited by

Grazia Pavia

and

Gianfranco Di Gennaro

submission deadline 31 Jul 2025 | 6 articles | Viewed by 18670 | Submission Open

Keywords: host immune response; virulence determinants; pathogen-host interaction; immune responses; therapeutic strategies; vaccines

(This special issue belongs to the Section Pathogens-Host Immune Boundaries)

Immune Response After Respiratory Infection or Vaccination

edited by

Dingmei Zhang

submission deadline 31 Jul 2025 | 9 articles | Viewed by 14877 | Submission Open

Keywords: immune response to viral co-infections; immune memory in response to co-infections; influenza and coronavirus vaccines; vaccines for co-infections

(This special issue belongs to the Section Vaccines, Clinical Advancement, and Associated Immunology)

Recent Discoveries and Developments in RNA and DNA Vaccines

edited by

Hang Fai (Henry) Kwok

submission deadline 31 Jul 2025 | 3 articles | Viewed by 10921 | Submission Open

Keywords: RNA vaccine; DNA vaccine; prevention; therapy; delivery system; lipid nanoparticles; infectious diseases; immune response; cancer

(This special issue belongs to the Section Nucleic Acid (DNA and mRNA) Vaccines)

Clinical Strategies to Improve Efficacy, Effectiveness, and Safety of Vaccination in Humans

edited by

Kay Choong See

submission deadline 31 Jul 2025 | 6 articles | Viewed by 8749 | Submission Open

Keywords: adenovirus vaccines; immunologic adjuvants; adult; communicable diseases; geriatrics; immunocompromised Host; mRNA vaccines; pediatrics; public health; attenuated vaccines; inactivated vaccines

(This special issue belongs to the Section Vaccine Advancement, Efficacy and Safety)

Latest Researches on Flavivirus Vaccines II

edited by

Florian Douam

submission deadline 31 Jul 2025 | 3 articles | Viewed by 7785 | Submission Open

Keywords: flavivirus vaccines; vaccine development; Dengue Virus; Yellow Fever Virus; West Nile Virus; Zika Virus; tick-borne encephalitis virus; immunization

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Parasitic Infections: Therapy for Host Immunity and Vaccination

edited by José Manuel Molina Caballero and Antonio Ruiz Reyes

submission deadline 31 Jul 2025 | 3 articles | Viewed by 7048 | Submission Open

Keywords: immune response; parasites; helminths; arthropods; protozoa; therapy; vaccination

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Dendritic Cells (DCs) and Cancer Immunotherapy

edited by

Aimin Jiang

submission deadline 31 Jul 2025 | 3 articles | Viewed by 6124 | Submission Open

Keywords: dendritic cell vaccine; cancer immunotherapy; immune checkpoint blockade; tumor immunity; CD8 T cell immunity; exosomes

(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)

Innovating Vaccine Research in Mucosal Vaccines

edited by Ana Rosa Pérez, Iván Marcipar and Gabriel Cabrera

submission deadline 31 Jul 2025 | 3 articles | Viewed by 5655 | Submission Open

Keywords: mucosal vaccines; mucosal delivery systems; mucosal adjuvants; oral vaccines; nasal vaccines; genital vaccines

(This special issue belongs to the Section Vaccines, Clinical Advancement, and Associated Immunology)

Current Advances in mRNA Vaccines for Infectious Diseases and Cancer Immunotherapy

edited by Sushma M. Bhosle

submission deadline 31 Jul 2025 | 2 articles | Viewed by 4818 | Submission Open

Keywords: mRNA design; vaccines; infectious disease; cancer immunotherapy; self-amplifying mRNA; adjuvants; organ-on-chip; mRNA stability; immune response; clinical trials

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Immunization of Immunosuppressed Patients

edited by

Massimo Franchini

and

Daniele Focosi

submission deadline 31 Jul 2025 | 4 articles | Viewed by 3957 | Submission Open

Keywords: COVID-19; vaccine efficacy; immunization

(This special issue belongs to the Section COVID-19 Vaccines and Vaccination)

Mucosal Immunity and Vaccine

edited by Xingmin Sun and

Yongqun He (Oliver)

submission deadline 31 Jul 2025 | 2 articles | Viewed by 2844 | Submission Open

Keywords: mucosal immunity; vaccine; mucosal adjuvant

(This special issue belongs to the Section Vaccines, Clinical Advancement, and Associated Immunology)

Advances in Vaccination Against Tick-Borne Pathogens

edited by

Artur Sulik

and

Kacper Toczylowski

submission deadline 31 Jul 2025 | 2 articles | Viewed by 2835 | Submission Open

Keywords: tick-borne diseases; tick-borne encephalitis; Lyme disease; Lyme disease vaccine; ticks; immunization

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Vaccines Against Enteric Bacterial Pathogens in Poultry

edited by

Khaled Abdelaziz

and

Ahmed Ali

submission deadline 31 Jul 2025 | 1 articles | Viewed by 2785 | Submission Open

Keywords: vaccine; immunomodulators; adjuvants; chicken; poultry; bacteria; necrotic enteritis; Clostridium perfringens; Salmonella; Campylobacter; E. coli; Listeria

(This special issue belongs to the Section Veterinary Vaccines)

Immunogenicity, Safety, and Coverage of Vaccines in Patients with Autoimmune Diseases

edited by

Andrea Picchianti-Diamanti

and

Delia Goletti

submission deadline 31 Jul 2025 | 2 articles | Viewed by 2427 | Submission Open

Keywords: vaccines; systemic autoimmune diseases; bDMARDs; tsDMARDs; immunosuppressive therapy; adverse events; immunogenicity; coverage rates; specific T cell response

(This special issue belongs to the Section Vaccines, Clinical Advancement, and Associated Immunology)

Vaccines for Porcine Viruses

edited by Hongxia Wu

submission deadline 31 Jul 2025 | 2 articles | Viewed by 1969 | Submission Open

Keywords: infections; vaccine; adaptive immune response; epidemiology

(This special issue belongs to the Section Veterinary Vaccines)

Human Leukocyte Antigen (HLA)—Antigen Interactions in Vaccine Development

edited by

Apostolos P. Georgopoulos

submission deadline 31 Jul 2025 | 1 articles | Viewed by 1842 | Submission Open

Keywords: vaccine; antigen; antibody; adjuvant; HLA; binding affinity; lymphocytes; antigen presenting cells

(This special issue belongs to the Section Pathogens-Host Immune Boundaries)

Treating Autoimmune Diseases with Vaccination

edited by

Ritu Chakravarti

submission deadline 31 Jul 2025 | Viewed by 238 | Submission Open

Keywords: autoimmune disease; immune regulations; immune tolerance; antigen therapy; vaccine; immunizations

(This special issue belongs to the Section Vaccines, Clinical Advancement, and Associated Immunology)

Cytokines and Cytokine Receptors in Inflammation and Immunity

edited by

Pedro A. Reche

and Vassili Soumelis

submission deadline 31 Jul 2025 | Viewed by 238 | Submission Open

Keywords: cytokine; cytokine receptors; chemokine; inlammation; immunity; signaling; immunotherapy

State of the Art of Flavivirus Virus Research

edited by

Tomoyoshi Komiya

submission deadline 31 Jul 2025 | Viewed by 193 | Submission Open

Keywords: flavivirus; vaccine; infection control; diagnosis; epidemiology

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Recent Scientific Advances in Vaccination Strategies for Viral Haemorrhagic Fevers

edited by

Daniela Manno

submission deadline 31 Jul 2025 | Viewed by 144 | Submission Open

Keywords: viral haemorrhagic fevers; Ebola virus disease; Sudan virus disease; Marburg virus disease; Lassa fever; Rift Valley fever; Crimean– Congo haemorrhagic fever; vaccination strategies; outbreak preparedness; epidemiology of VHFs

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Recent Research on Neutralizing Antibody Response to SARS-CoV-2 Variants

edited by

Chloé Dimeglio

submission deadline 6 Aug 2025 | 2 articles | Viewed by 3189 | Submission Open

Keywords: SARS-CoV-2 and vaccines; SARS-CoV-2 and natural infection; immunity mechanism; competition between variants; SARS-CoV-2 dynamics

(This special issue belongs to the Section COVID-19 Vaccines and Vaccination)

Veterinary Vaccines and Host Immune Responses

edited by Ayumi Matsuyama-Kato and

Faizal Careem

submission deadline 13 Aug 2025 | 9 articles | Viewed by 10569 | Submission Open

Keywords: animal vaccine; vaccine delivery; immune response; adjuvant; antibody-mediated immunity; cell-mediated immunity; immunogenicity; veterinary immunology

(This special issue belongs to the Section Veterinary Vaccines)

Vaccine Acceptance and Coverage

edited by

Ryoko Sato

and

Christian Napoli

submission deadline 15 Aug 2025 | 2 articles | Viewed by 3353 | Submission Open

Keywords: vaccine; vaccination; vaccine acceptance; vaccine hesitancy; vaccination coverage; immunization coverage

(This special issue belongs to the Section Vaccines and Public Health)

Immune Correlates of Protection in Vaccines, 2nd Edition

edited by

Jingyou Yu

submission deadline 16 Aug 2025 | 1 articles | Viewed by 1461 | Submission Open

Keywords: vaccine; humoral immunity; cellular immunity; innate immunity; infectious disease; virus; cancer

(This special issue belongs to the Section Vaccines, Clinical Advancement, and Associated Immunology)

Impact of Immunization Safety Monitoring on Vaccine Coverage

edited by Jane F. Gidudu

submission deadline 25 Aug 2025 | 8 articles | Viewed by 10276 | Submission Open

Keywords: vaccine safety; immunization safety; adverse events following immunization; vaccination coverage; vaccine hesitancy; pharmacovigilance; information systems; active surveillance; mis- and dis-information

(This special issue belongs to the Section Vaccines and Public Health)

Immune Responses in Patients with Chronic Disease After Vaccination

edited by

Nikola Stojanović

and

Marko Baralic

submission deadline 30 Aug 2025 | 1 articles | Viewed by 685 | Submission Open

Keywords: immunity; vaccine; chronic kidney disease; glomerulonephritis; systemic lupus erythematosus; vasculitis; kidney transplant; schizophrenia; bipolar disorder; diabetes

(This special issue belongs to the Section Vaccines, Clinical Advancement, and Associated Immunology)

New Trends in Vaccine Characterization, Formulations, and Development

edited by

Ravinder Kumar

submission deadline 31 Aug 2025 | 12 articles | Viewed by 51388 | Submission Open

Keywords: vaccines; formulation; development; vaccine delivery; mRNA vaccines; DNA vaccines; subunit vaccine; adjuvant; yeast-based vaccines; virus-like particles (VLPs); surface display; production process; quality control

Biotechnologies Applied in Vaccine Research

edited by

Yuan-Chuan Chen

submission deadline 31 Aug 2025 | 5 articles | Viewed by 21299 | Submission Open

Keywords: vaccine; biotechnology; vector; nanoparticle; virus; bacteria; recombination DNA; mRNA; subunit; adjuvant; delivery

Strategies of Viral Vectors for Vaccine Development

edited by

Kathleen Hefferon

submission deadline 31 Aug 2025 | 7 articles | Viewed by 15167 | Submission Open

Keywords: vaccine; viral vector; virus-like particles

(This special issue belongs to the Section Vaccine Design, Development, and Delivery)

Novel Vaccines and Vaccine Technologies for Emerging Infections

edited by

Wangxue Chen

Xuguang Li

and

Amine A. Kamen

submission deadline 31 Aug 2025 | 5 articles | Viewed by 14078 | Submission Open

Keywords: novel vaccines and adjuvant; universal vaccines; mucosal vaccines; emerging infections; antimicrobial resistance; systems vaccinology; vaccine production

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Vaccine Uptake in Italy, Through the OBVIOUS Project and Other Independent Research

edited by

Jacopo Lenzi

and

Davide Gori

submission deadline 31 Aug 2025 | 6 articles | Viewed by 13754 | Submission Open

Keywords: vaccine uptake; vaccine hesitancy; vaccination rates; Italy

(This special issue belongs to the Section Epidemiology and Vaccination)

Vaccines Targeting the Tumor Microenvironment: Challenges and Future Prospects

edited by

Walter J. Storkus

and Devin Lowe

submission deadline 31 Aug 2025 | 8 articles | Viewed by 12450 | Submission Open

Keywords: vaccine; adoptive cell therapy; CAR-T cells; immune checkpoint inhibitors; immunotherapy; stroma; tumor microenvironment

(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)

Advancing the Science on Vaccine Hesitancy to Inform Interventions

edited by Kimberly H. Nguyen and

Jennifer Allen

submission deadline 31 Aug 2025 | 6 articles | Viewed by 10812 | Submission Open

Keywords: vaccine hesitancy; vaccine confidence; COVID-19; routinely recommended vaccines; epidemiologic methods; conceptual frameworks; strategies; surveillance

(This special issue belongs to the Section Vaccines and Public Health)

Advances in Glycoconjugate Vaccines and Nanovaccines

edited by

Marco Terreni

and

Sara Tengattini

submission deadline 31 Aug 2025 | 4 articles | Viewed by 10372 | Submission Open

Keywords: glycoconjugate vaccines; infection diseases; anticancer vaccines; glycosylated nanovaccines; antigenic saccharides; conjugation chemistry; glycoconjugate characterization; dual-acting vaccines; glycosylated nanoparticles

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Respiratory Syncytial Virus (RSV) Vaccine

edited by

Surender Khurana

submission deadline 31 Aug 2025 | 4 articles | Viewed by 8621 | Submission Open

Keywords: respiratory syncytial virus (RSV); RSV vaccine development; viral vector vaccines; subunit vaccines; prefusion protein design; mRNA vaccines; vaccine efficacy; immunization strategies

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Role of Gut Microbiota in Immune Tolerance and Vaccine Development

edited by

Sin-Hyeog Im

submission deadline 31 Aug 2025 | 2 articles | Viewed by 5663 | Submission Open

Keywords: immune tolerance; subtype of immune cells; microbiome; probiotics; T cells; B cells; dendritic cells; antigen-presenting cells

(This special issue belongs to the Section Vaccines, Clinical Advancement, and Associated Immunology)

Understanding Infectious Disease Vaccinations: Implications for Health and Safety

edited by

Daniel Kwasi Ahorsu

submission deadline 31 Aug 2025 | 3 articles | Viewed by 3073 | Submission Open

Keywords: vaccination; infectious disease; health; wellbeing; knowledge; attitudes

(This special issue belongs to the Section Vaccines and Public Health)

Vaccination Against Vector-Borne Diseases: Bridging Public Health and Epidemiology

edited by

Angela Stufano

and

Claudia Maria Trombetta

submission deadline 31 Aug 2025 | 2 articles | Viewed by 1888 | Submission Open

Keywords: vector-borne diseases; vaccination strategies; epidemiology; public health integration; disease prevention

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Vaccine Hesitancy and Acceptance: A Public Health Perspective

edited by

Neli Ragina

and

Michael J. Conway

submission deadline 31 Aug 2025 | 1 articles | Viewed by 1644 | Submission Open

Keywords: vaccine hesitancy; vaccine acceptance; public health; vaccine uptake; misinformation; risk perception; health communication; immunization rates; herd immunity; behavioral determinants; social determinants; trust in healthcare; vaccine misinformation; vaccine education; vaccine refusal; vaccine policy; health disparities

(This special issue belongs to the Section Vaccines and Public Health)

Vaccines Against Flaviviruses and Alphaviruses: Recent Advances and Future Challenges—2nd Edition

edited by

Arturo Reyes-Sandoval

and

Young Chan Kim

submission deadline 31 Aug 2025 | 1 articles | Viewed by 1209 | Submission Open

Keywords: vaccine; arbovirus; flavivirus; alphavirus; vaccines; preclinical; animal model; challenge studies; clinical trials

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Childhood Immunization and Public Health

edited by Carsten Krüger

submission deadline 31 Aug 2025 | 1 articles | Viewed by 1052 | Submission Open

Keywords: compulsory/mandatory vaccination; coverage; local vaccination culture; pandemics; trust; vaccination frameworks; vaccine equity; vaccine hesitancy; zero-dose

(This special issue belongs to the Section Vaccines and Public Health)

Strategies for Addressing Vaccine Hesitancy

edited by