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Vaccines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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New Technology for Vaccines and Vaccine-Preventable Diseases

edited by

Jue Liu

submission deadline 20 Oct 2025 | 2 articles | Viewed by 2018 | Submission Open

Keywords: artificial intelligence in vaccines; big data in vaccine research; emerging infectious diseases; vaccine accessibility; vaccine delivery systems; vaccine efficacy and safety; vaccine-preventable diseases; vaccine technology

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Immunization Strategies for Animal Health

edited by Eva Calvo-Pinilla and

Alejandro Marin-Lopez

submission deadline 31 Oct 2025 | 6 articles | Viewed by 23990 | Submission Open

Keywords: vaccine immunology; virus; emerging infectious disease; animal health; public health; vaccination

(This special issue belongs to the Section Veterinary Vaccines)

Promoting Research, Development and Access to Vaccines to Address Global Inequities

edited by

Yangmu Huang

submission deadline 31 Oct 2025 | 5 articles | Viewed by 12862 | Submission Open

Keywords: research and development; communicable diseases; vulnerable population; medical countermeasures; vaccine-preventable diseases; innovative vaccines; vaccine hesitancy; health education; vaccination coverage rates; vaccination strategies

(This special issue belongs to the Section Vaccine Advancement, Efficacy and Safety)

Viral Vector-Based Vaccines and Therapeutics

edited by Sujit Pujhari

submission deadline 31 Oct 2025 | 6 articles | Viewed by 10880 | Submission Open

Keywords: viral vectors; vaccine technology; gene therapy; immunization strategies; vector design; vaccine safety; vector-based therapeutics

(This special issue belongs to the Section Vaccine Design, Development, and Delivery)

Vaccine Development for Swine Viral Pathogens

edited by Qingli Niu

submission deadline 31 Oct 2025 | 6 articles | Viewed by 10358 | Submission Open

Keywords: vaccine engineering; design; formulation; adjuvants; delivery; testing

(This special issue belongs to the Section Veterinary Vaccines)

Next-Generation Vaccines for Animal Infectious Diseases

edited by Yongwen Luo, Huiying Fan and Qing Wang

submission deadline 31 Oct 2025 | 6 articles | Viewed by 9857 | Submission Open

Keywords: LNP-mRNA vaccines; VLP vaccines; polymeric/inorganic nanoparticle vaccines; self-assembled protein vaccines; biomimetic nanoparticle vaccines; novel vector-based vaccines; new adjuvanted vaccines; nanovaccines

(This special issue belongs to the Section Veterinary Vaccines)

Vaccines Targeting Dendritic Cells

edited by Ronald A. Backer and Björn E. Clausen

submission deadline 31 Oct 2025 | 4 articles | Viewed by 8707 | Submission Open

Keywords: vaccines; dendritic cells; antigen targeting; immune responses; adjuvant; cancer immunotherapy; T cell activation

(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)

Animal Diseases: Immune Response and Vaccines

edited by

Verónica Martín

, José M. Rojas and

Noemí Sevilla

submission deadline 31 Oct 2025 | 7 articles | Viewed by 8495 | Submission Open

Keywords: immune responses; ruminants; vaccines; animal health

(This special issue belongs to the Section Veterinary Vaccines)

Acceptance and Hesitancy in Vaccine Uptake: 2nd Edition

edited by Sherri Sheinfeld Gorin

submission deadline 31 Oct 2025 | 6 articles | Viewed by 7642 | Submission Open

Keywords: vaccine acceptance; vaccine hesitancy; vaccine uptake; vaccination

(This special issue belongs to the Section Vaccines and Public Health)

New Approaches to Vaccine Development and Delivery

edited by

Antonio Carlos de Freitas

submission deadline 31 Oct 2025 | 5 articles | Viewed by 7440 | Submission Open

Keywords: vaccines; formulation; vaccine delivery; yeast-based vaccines; surface display; yeast shell; delivery systems; mRNA vaccines; DNA vaccines; subunit vaccine; adjuvant; virus-like particles (VLPs); quality control

(This special issue belongs to the Section Vaccine Advancement, Efficacy and Safety)

Humoral and Cellular Response After Vaccination

edited by Adrian Onu and Iuliana Caras

submission deadline 31 Oct 2025 | 2 articles | Viewed by 5398 | Submission Open

Keywords: vaccine; infectious disease; humoral immunity; cellular immunity; innate immunity; trained immunity; pathogen; virus

(This special issue belongs to the Section Vaccines, Clinical Advancement, and Associated Immunology)

HIV Vaccine Development and Clinical Trails

edited by Massimiliano Bissa

submission deadline 31 Oct 2025 | 2 articles | Viewed by 5324 | Submission Open

Keywords: HIV vaccine; HIV vaccine clinical trial; HIV vaccine adjuvant; correlate of decreased HIV risk; HIV immunogen; broadly neutralizing antibodies

(This special issue belongs to the Section HIV Vaccines)

Personalised Cancer Vaccines

edited by Andrew L. Coveler

submission deadline 31 Oct 2025 | 2 articles | Viewed by 3980 | Submission Open

Keywords: peptide vaccines; mRNA vaccines; DNA vaccines; cancer vaccines

(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)

Novel Viral Vaccine and Molecular Immunology

edited by

Chang Li

submission deadline 31 Oct 2025 | 2 articles | Viewed by 3718 | Submission Open

Keywords: viral infectious diseases; novel vaccines; immune mechanism

(This special issue belongs to the Section Vaccines, Clinical Advancement, and Associated Immunology)

Advances in Allergy, Clinical Immunology, and Vaccines

edited by

Laura Franza

submission deadline 31 Oct 2025 | 1 articles | Viewed by 3586 | Submission Open

Keywords: immunology; allergology; allergy; autoimmunity; biomarkers; environment; pollution

(This special issue belongs to the Section Vaccines, Clinical Advancement, and Associated Immunology)

Infectious Diseases and Immunization in Animals

edited by

Fábio Abade dos Santos

, Ezgi Akdesir and

Jelena Prpić

submission deadline 31 Oct 2025 | 3 articles | Viewed by 2316 | Submission Open

Keywords: animal vaccination; zoonotic diseases; One Health; host– pathogen interaction; veterinary immunology; emerging infectious diseases; antimicrobial resistance; vaccine development

(This special issue belongs to the Section Veterinary Vaccines)

Research in Vaccine Adjuvants: Innovations and Challenges

edited by Haibo Li and

Hongwu Sun

submission deadline 31 Oct 2025 | 1 articles | Viewed by 1965 | Submission Open

Keywords: vaccine adjuvants; immune response enhancement; mucosal vaccine adjuvants; adjuvant safety and efficacy; new adjuvant materials; adjuvant mechanisms of action; adjuvant development challenges

(This special issue belongs to the Section Vaccine Design, Development, and Delivery)

The Development of Peptide-Based Vaccines

edited by

José Manuel Pérez De La Lastra

and

José de la Fuente

submission deadline 31 Oct 2025 | 1 articles | Viewed by 1208 | Submission Open

Keywords: peptide antigens; vaccine design; immunogenicity; epitope mapping; adjuvants; multi-epitope vaccines; personalized peptide vaccines; vaccine delivery systems; computational vaccine design; synthetic peptides

Antiviral Immunity and Vaccine Development

edited by

Caijun Sun

and Tao Yu

submission deadline 31 Oct 2025 | 1 articles | Viewed by 1173 | Submission Open

Keywords: antiviral innate immunity; adaptive immune responses; viral pathogenesis; immune evasion; host– virus interactions; antiviral vaccine development; vaccine design; novel vaccine platforms; vaccine adjuvants; vaccines and therapeutics

(This special issue belongs to the Section Pathogens-Host Immune Boundaries)

The Development of Recombinant and Subunit Vaccines Against Infectious Diseases

edited by

Abu Salim Mustafa

submission deadline 31 Oct 2025 | Viewed by 659 | Submission Open

Keywords: infectious diseases; vaccines; recombinant antigens; adjuvants

(This special issue belongs to the Section Vaccines against Infectious Diseases)

Pandemic Influenza Vaccination

edited by Francisco Nogareda and Shoshanna Goldin

submission deadline 31 Oct 2025 | Viewed by 636 | Submission Open

Keywords: pandemic influenza; vaccines; zoonotic influenza; influenza A/H5; preparedness; response

(This special issue belongs to the Section Influenza Virus Vaccines)

Bioengineering in Vaccine Design and Delivery

edited by

Massimo Zollo

submission deadline 1 Nov 2025 | 3 articles | Viewed by 8903 | Submission Open

Keywords: vaccine design; vaccine delivery; vaccine synthesis; vaccine carriers; virus-like particles

(This special issue belongs to the Section Vaccine Design, Development, and Delivery)

Immunobiology of Mycobacterium tuberculosis and Its Implication in Vaccine Design

edited by Tony W. Ng and Steven A. Porcelli

submission deadline 1 Nov 2025 | 2 articles | Viewed by 4170 | Submission Open

Keywords: Mycobacterium tuberculosis; polyfunctional T cells; antibodies; trained immunity; vaccination routes; non-human primates; persisters; auxotrophs; adjuvants

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Molecular Virology and Translational Research in Antiviral Vaccine Development

edited by

Safder Ganaie

submission deadline 20 Nov 2025 | Viewed by 341 | Submission Open

Keywords: molecular virology; antiviral development; vaccine design; host– pathogen interactions; viral entry and replication; immune evasion; structural virology; emerging and re-emerging viruses; zoonotic viruses

COVID Vaccines: Design, Development, and Immune Response Studies: 2nd Edition

edited by

Fabrizio Maggi

and

Licia Bordi

submission deadline 30 Nov 2025 | 22 articles | Viewed by 110854 | Submission Open

Keywords: COVID-19 vaccine; mucosal immunity; immune response; SARS-CoV-2; vaccine design

(This special issue belongs to the Section COVID-19 Vaccines and Vaccination)

Feature Papers of DNA and mRNA Vaccines

edited by

Jorge H. Leitão

submission deadline 30 Nov 2025 | 10 articles | Viewed by 52657 | Submission Open

(This special issue belongs to the Section Nucleic Acid (DNA and mRNA) Vaccines)

Advance Public Health Through Vaccination

edited by

Gianluca Voglino

, Maria Rosaria Gualano,

Giuseppina Lo Moro

and

Erica De Vita

submission deadline 30 Nov 2025 | 16 articles | Viewed by 39470 | Submission Open

Keywords: epidemiology; vaccination strategies; vaccine hesitancy; health equity; vulnerable population

(This special issue belongs to the Section Vaccines and Public Health)

Cancer Vaccines and Immunotherapy: Latest Advances, Limitations and Prospects

edited by

Eyad Elkord

and Afsheen Raza

submission deadline 30 Nov 2025 | 4 articles | Viewed by 12936 | Submission Open

Keywords: cancer; tumor microenvironment; tumor immunotherapy; therapy; cancer vaccines; combination therapy; tumor immune microenvironment; advanced therapies; biomarkers

(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)

Vaccine Efficacy and Safety in Patients with Immune-Mediated Intestinal Diseases

edited by

Adi Lahat

and

Kassem Sharif

submission deadline 30 Nov 2025 | 5 articles | Viewed by 10555 | Submission Open

Keywords: inflammatory bowel disease (IBD); Crohn’ s disease; ulcerative colitis; celiac disease; vaccines; immune-mediated intestinal disease

(This special issue belongs to the Section Vaccine Advancement, Efficacy and Safety)

Advanced Concepts in Vaccines in Public Health

edited by Maria Elena Flacco

submission deadline 30 Nov 2025 | 4 articles | Viewed by 9549 | Submission Open

Keywords: vaccines; vaccine safety; vaccine efficacy; vaccine hesitancy; new vaccines; vaccine cost-effectiveness

(This special issue belongs to the Section Vaccines and Public Health)

Population Immunity and Persistence to SARS-CoV-2 Induced by Infection and Vaccination, Protection Against New Infections and Implication for Further Vaccination: 2nd Edition

edited by Juan Yang and Wei Wang

submission deadline 30 Nov 2025 | 4 articles | Viewed by 7796 | Submission Open

Keywords: SARS-CoV-2; COVID-19; serology; population immunity; hybrid immunity; vaccination; antibody kinetics; cross-protection

(This special issue belongs to the Section COVID-19 Vaccines and Vaccination)

Advances in HIV Vaccine Development, 2nd Edition

edited by

Xueling Wu

submission deadline 30 Nov 2025 | 2 articles | Viewed by 5987 | Submission Open

Keywords: HIV; envelope glycoprotein; vaccine; adjuvant; antibody; neutralization; ADCC; ADCP; complement; cellular immune response

(This special issue belongs to the Section HIV Vaccines)

The Vaccine Development and Study of Swine Diseases

edited by

Chunhe Guo

submission deadline 30 Nov 2025 | 1 articles | Viewed by 3133 | Submission Open

Keywords: swine diseases; viruses; vaccines; protection; control

(This special issue belongs to the Section Veterinary Vaccines)

Intracellular Parasites: Immunology, Resistance, and Therapeutics

edited by

Rajesh Mani

and Nagendran Tharmalingam

submission deadline 30 Nov 2025 | 1 articles | Viewed by 2941 | Submission Open

Keywords: intracellular parasites; host– parasite interaction; chronic parasitic infections; innate and adaptive immunity; molecular genetics; immune evasion; antibiotic resistance; immune modulation; immunotherapy; vaccine development; biomaterials; nanoparticles

(This special issue belongs to the Section Pathogens-Host Immune Boundaries)

Bacterial and Viral Infections: Current Challenges and Vaccine Innovations

edited by Dima El Safadi

submission deadline 30 Nov 2025 | 3 articles | Viewed by 2451 | Submission Open

Keywords: bacterial and viral infections; vaccine platforms; antimicrobial resistance; vaccine effectiveness; vaccine access and equity; global health

(This special issue belongs to the Section Pathogens-Host Immune Boundaries)

New Insights into Vaccination and Public Health: 2nd Edition

edited by

Paolo Castiglia

and

Antonella Arghittu

submission deadline 30 Nov 2025 | 1 articles | Viewed by 2142 | Submission Open

Keywords: innovative vaccines; vaccine hesitancy; vaccination strategies; health communication; vaccine-preventable diseases

(This special issue belongs to the Section Vaccines and Public Health)

Animal Infectious Diseases and Vaccinology in One Health

edited by

Edith Rojas-Anaya

and Elizabeth Loza-Rubio

submission deadline 30 Nov 2025 | 2 articles | Viewed by 1973 | Submission Open

Keywords: vaccinology; productive animals; one health; infectious diseases; zoonoses

(This special issue belongs to the Section Veterinary Vaccines)

Cost-Effectiveness of Vaccines and Public Health

edited by Sachin A. Silva

submission deadline 30 Nov 2025 | 1 articles | Viewed by 1361 | Submission Open

Keywords: cost-effectiveness; public health value; vaccines; valuation; vaccination; immunization; benefit– cost; welfare; extended cost-effectiveness; QALYs

(This special issue belongs to the Section Vaccines and Public Health)

Vaccines Design Against Porcine Circovirus

edited by

Jianli Shi

Junki Maruyama

and

Takeshi Saito

submission deadline 30 Nov 2025 | Viewed by 591 | Submission Open

Keywords: porcine circovirus; vaccine; new adjuvants; evaluation method

(This special issue belongs to the Section Veterinary Vaccines)

Advances in the Use of Nanoparticles for Vaccine Platform Development: 2nd Edition

edited by

Imran Saleem

submission deadline 30 Nov 2025 | 1 articles | Viewed by 589 | Submission Open

Keywords: nanoparticles; vaccine; immunotherapy; subunit vaccine; RNA vaccine; adjuvant; nanotechnology

(This special issue belongs to the Section Vaccine Design, Development, and Delivery)

Tuberculosis Diagnosis and Vaccines Research

edited by Shumaila Nida Javed Tunio

submission deadline 30 Nov 2025 | Viewed by 311 | Submission Open

Keywords: developing new diagnostic methods; new drugs; new vaccines for tuberculosis

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Vaccines for Porcine Coronaviruses

edited by

Jung-Eun Park

submission deadline 1 Dec 2025 | Viewed by 415 | Submission Open

Keywords: porcine coronavirus; porcine epidemic diarrhea virus (PEDV); transmissible gastroenteritis virus (TGEV); porcine deltacoronavirus (PDCoV); swine acute diarrhea syndrome coronavirus (SADS-CoV); porcine respiratory coronavirus (PRCV); porcine hemagglutinating encephalomyelitis virus (PHEV); vaccine; immune response; protective efficacy

(This special issue belongs to the Section Veterinary Vaccines)

Vaccination and Public Health in the 21st Century

edited by

Evridiki Patelarou

Enkeleint A. Mechili

and

Athina E. Patelarou

submission deadline 20 Dec 2025 | 10 articles | Viewed by 13945 | Submission Open

Keywords: vaccines; public health; clinical vaccine research; immunization; health technology assessment; vaccine development

(This special issue belongs to the Section Vaccines and Public Health)

Nanotechnology-Based Vaccines for the Prevention of Infectious Diseases

edited by Wandi Zhu

submission deadline 20 Dec 2025 | Viewed by 339 | Submission Open

Keywords: infectious diseases; nanoparticle vaccines; nanovaccine delivery; immune responses; vaccine adjuvant; immune protection; mucosal immunity

Human Immune Responses to Infection and Vaccination

edited by

Alexander Batista-Duharte

and

Gabriel Cabrera

submission deadline 31 Dec 2025 | 9 articles | Viewed by 17896 | Submission Open

Keywords: vaccine immunogenicity; adjuvants; new generation of vaccines; vaccine development; immune regulation; translational vaccinology; system vaccinology; herd immunity; vaccine safety; correlates of protection

(This special issue belongs to the Section Vaccines, Clinical Advancement, and Associated Immunology)

Evaluation of Vaccine Efficacy, Safety and Immunogenicity Against Influenza, RSV and COVID-19

edited by

Roland Zahn

submission deadline 31 Dec 2025 | 5 articles | Viewed by 13855 | Submission Open

Keywords: influenza; respiratory syncytial virus (RSV); COVID-19; SARS-CoV-2; vaccines; immunogenicity; efficacy; safety; universal vaccine

(This special issue belongs to the Section Vaccine Advancement, Efficacy and Safety)

Health Technology Assessment of Vaccination: Strategies, Public Health and Values

edited by Maarten J. Postma, Jurjen Van der Schans and

Cornelis Boersma

submission deadline 31 Dec 2025 | 5 articles | Viewed by 10625 | Submission Open

Keywords: health technology assessment; population access vaccine studies; vaccination cost-effectiveness; vaccine hesitancy

(This special issue belongs to the Section Vaccines and Public Health)

Vaccines Against Poultry Viruses

edited by

Xiuli Feng

submission deadline 31 Dec 2025 | 2 articles | Viewed by 9292 | Submission Open

Keywords: poultry and waterfowl; pigeons; wild birds; viral diseases; immunosuppressive disease; respiratory syndrome disease; poultry tumor diseases; immunoenhancers and adjuvants; genetically engineered vaccines; biosafety management of clinical veterinarians; antiviral drugs

(This special issue belongs to the Section Veterinary Vaccines)

The Current Development of Glycoconjugate Vaccines for Infectious Diseases

edited by Fatme Mawas

submission deadline 31 Dec 2025 | 4 articles | Viewed by 8000 | Submission Open

Keywords: bacterial vaccines; polysaccharides; conjugate vaccines; carrier proteins

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Vaccines for the Vulnerable Population

edited by

My Kieu Ha

submission deadline 31 Dec 2025 | 3 articles | Viewed by 7868 | Submission Open

Keywords: vaccines; vulnerable populations; infectious diseases; immunization

(This special issue belongs to the Section Vaccines and Public Health)

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