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Vaccines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Inequality in Immunization 2025

edited by

Ahmad Reza Hosseinpoor

and Ibrahim Dadari

submission deadline 15 Sep 2025 | 5 articles | Viewed by 6437 | Submission Open

Keywords: health inequalities; immunization; vaccine inequality; events affecting vaccinology; monitoring

(This special issue belongs to the Section Vaccines and Public Health)

Vaccination Strategies for Global Public Health

edited by

Mathumalar Fahrni

and

Antonio Ivan Lazzarino

submission deadline 30 Sep 2025 | 16 articles | Viewed by 38295 | Submission Open

Keywords: emerging infectious disease; SARS-CoV-2; human monkeypox; dengue; henipavirus; public health; population-based studies; modelling; social impact; equitable access; vaccination

(This special issue belongs to the Section Vaccines and Public Health)

Varicella and Zoster Vaccination

edited by

Peter Maple

submission deadline 30 Sep 2025 | 14 articles | Viewed by 33477 | Submission Open

Keywords: varicella-zoster virus; chickenpox; shingles; vaccination; epidemiology; geographical regions; neurological diseases; SARS-CoV-2

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Novel Vaccines and Vaccine Technologies for Emerging Infections

edited by

Wangxue Chen

Xuguang Li

and

Amine A. Kamen

submission deadline 30 Sep 2025 | 8 articles | Viewed by 20361 | Submission Open

Keywords: novel vaccines and adjuvant; universal vaccines; mucosal vaccines; emerging infections; antimicrobial resistance; systems vaccinology; vaccine production

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Peptide-Based Vaccines

edited by

Waleed Hussein

Mariusz Skwarczynski

and Ahmed O. Shalash

submission deadline 30 Sep 2025 | 4 articles | Viewed by 9960 | Submission Open

Keywords: peptide-based vaccines; infectious diseases; prophylactic vaccines; therapeutic vaccines; cancer; vaccine formulations; adjuvants

The Current Development of Glycoconjugate Vaccines for Infectious Diseases

edited by Fatme Mawas

submission deadline 30 Sep 2025 | 4 articles | Viewed by 7186 | Submission Open

Keywords: bacterial vaccines; polysaccharides; conjugate vaccines; carrier proteins

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Development of Vaccines Against Bacterial Infections

edited by

John Hwa Lee

and Amal Senevirathne

submission deadline 30 Sep 2025 | 4 articles | Viewed by 5689 | Submission Open

Keywords: novel vaccine formulations; bacterial pathogenesis mechanisms; immunogenicity assessment; vaccine efficacy studies; next-generation vaccine platforms; targeted antigen design; novel adjuvants; vaccine clinical trials; vaccine delivery systems; vaccine cross-protection

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Bioengineering Strategies for Developing Vaccines

edited by Chen Zhao and Jiayi Shu

submission deadline 30 Sep 2025 | 1 articles | Viewed by 2905 | Submission Open

Keywords: vaccine platform; antigen design; targeted delivery; mRNA; nanoparticle; artificial intelligence

Vaccine Hesitancy and Acceptance

edited by Karl Hess, Jeff Goad and Laressa Bethishou

submission deadline 30 Sep 2025 | 2 articles | Viewed by 2402 | Submission Open

Keywords: vaccine hesitancy; vaccine acceptance; barriers to vaccination; vaccination strategies

(This special issue belongs to the Section Vaccines and Public Health)

3rd Edition: Safety and Autoimmune Response to SARS-CoV-2 Vaccination

edited by

Minghui Yang

submission deadline 30 Sep 2025 | 2 articles | Viewed by 2303 | Submission Open

Keywords: COVID-19 vaccine; vaccine efficacy; vaccine safety; adverse events following immunization

(This special issue belongs to the Section COVID-19 Vaccines and Vaccination)

Vaccine Hesitancy in the Era of COVID-19

edited by

and

submission deadline 30 Sep 2025 | Viewed by 616 | Submission Open

Keywords: vaccine hesitancy; evidence synthesis; COVID-19

(This special issue belongs to the Section Vaccines and Public Health)

Animal Vaccines: 2nd Edition

edited by

Hsian-Yu Wang

and

David Benfield

submission deadline 30 Sep 2025 | Viewed by 428 | Submission Open

Keywords: animal vaccines; novel antigen or adjuvant design; vaccine technologies

(This special issue belongs to the Section Veterinary Vaccines)

Vaccine Against Sexually Transmitted Diseases

edited by Weiming Tang

submission deadline 30 Sep 2025 | Viewed by 351 | Submission Open

Keywords: vaccination; sexually transmitted infections; HPV; HIV; syphilis; gonorrhea; and chlamydia; vaccine development; public health; epidemiology; health equity; preventive strategies

(This special issue belongs to the Section HIV Vaccines)

Innovations in Immunotherapy: Advancements in Cancer Vaccines and Immune Modulation

edited by

Nan Zhang

and

Hao Zhang

submission deadline 30 Sep 2025 | Viewed by 250 | Submission Open

Keywords: multi-omics; cancer therapy; precision medicine; cancer vaccines

(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)

Virus-Like Particle (VLP) Vaccines Against Emerging Infectious Diseases—2nd Edition

edited by

Gang Ye

submission deadline 30 Sep 2025 | Viewed by 207 | Submission Open

Keywords: emerging infectious diseases (EIDs); virus-like particle (VLP); vaccines

(This special issue belongs to the Section Vaccine Design, Development, and Delivery)

Factors Affecting Influenza Vaccine Uptake

edited by

Adriana Pistol

submission deadline 20 Oct 2025 | 1 articles | Viewed by 1757 | Submission Open

Keywords: influenza; vaccines; coverage; uptake; hesitancy; risk groups

(This special issue belongs to the Section Influenza Virus Vaccines)

New Technology for Vaccines and Vaccine-Preventable Diseases

edited by

Jue Liu

submission deadline 20 Oct 2025 | 2 articles | Viewed by 1608 | Submission Open

Keywords: artificial intelligence in vaccines; big data in vaccine research; emerging infectious diseases; vaccine accessibility; vaccine delivery systems; vaccine efficacy and safety; vaccine-preventable diseases; vaccine technology

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Viral Vector-Based and Other Vaccine Strategies for Poultry and Livestock

edited by Mathias Martins

submission deadline 20 Oct 2025 | Viewed by 412 | Submission Open

Keywords: vaccine strategies; viral vector-based vaccines; poultry; livestock; infectious diseases; immune responses; vaccine platforms; genetic engineering; veterinary medicine; antigen delivery

(This special issue belongs to the Section Veterinary Vaccines)

Vaccines Against Influenza and Other Respiratory Virus Infections

edited by

Santosh Dhakal

submission deadline 20 Oct 2025 | Viewed by 232 | Submission Open

Keywords: adjuvants; influenza; mucosal immunity; respiratory viral pathogens; vaccine effectiveness; vaccine safety

(This special issue belongs to the Section Influenza Virus Vaccines)

Immunization Strategies for Animal Health

edited by Eva Calvo-Pinilla and

Alejandro Marin-Lopez

submission deadline 31 Oct 2025 | 6 articles | Viewed by 20238 | Submission Open

Keywords: vaccine immunology; virus; emerging infectious disease; animal health; public health; vaccination

(This special issue belongs to the Section Veterinary Vaccines)

Promoting Research, Development and Access to Vaccines to Address Global Inequities

edited by

Yangmu Huang

submission deadline 31 Oct 2025 | 5 articles | Viewed by 10254 | Submission Open

Keywords: research and development; communicable diseases; vulnerable population; medical countermeasures; vaccine-preventable diseases; innovative vaccines; vaccine hesitancy; health education; vaccination coverage rates; vaccination strategies

(This special issue belongs to the Section Vaccine Advancement, Efficacy and Safety)

Viral Vector-Based Vaccines and Therapeutics

edited by Sujit Pujhari

submission deadline 31 Oct 2025 | 6 articles | Viewed by 10012 | Submission Open

Keywords: viral vectors; vaccine technology; gene therapy; immunization strategies; vector design; vaccine safety; vector-based therapeutics

(This special issue belongs to the Section Vaccine Design, Development, and Delivery)

Vaccine Development for Swine Viral Pathogens

edited by Qingli Niu

submission deadline 31 Oct 2025 | 6 articles | Viewed by 9248 | Submission Open

Keywords: vaccine engineering; design; formulation; adjuvants; delivery; testing

(This special issue belongs to the Section Veterinary Vaccines)

Next-Generation Vaccines for Animal Infectious Diseases

edited by Yongwen Luo, Huiying Fan and Qing Wang

submission deadline 31 Oct 2025 | 5 articles | Viewed by 8622 | Submission Open

Keywords: LNP-mRNA vaccines; VLP vaccines; polymeric/inorganic nanoparticle vaccines; self-assembled protein vaccines; biomimetic nanoparticle vaccines; novel vector-based vaccines; new adjuvanted vaccines; nanovaccines

(This special issue belongs to the Section Veterinary Vaccines)

Vaccines Targeting Dendritic Cells

edited by Ronald A. Backer and Björn E. Clausen

submission deadline 31 Oct 2025 | 4 articles | Viewed by 7609 | Submission Open

Keywords: vaccines; dendritic cells; antigen targeting; immune responses; adjuvant; cancer immunotherapy; T cell activation

(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)

Animal Diseases: Immune Response and Vaccines

edited by

Verónica Martín

, José M. Rojas and

Noemí Sevilla

submission deadline 31 Oct 2025 | 5 articles | Viewed by 7394 | Submission Open

Keywords: immune responses; ruminants; vaccines; animal health

(This special issue belongs to the Section Veterinary Vaccines)

Acceptance and Hesitancy in Vaccine Uptake: 2nd Edition

edited by Sherri Sheinfeld Gorin

submission deadline 31 Oct 2025 | 6 articles | Viewed by 6568 | Submission Open

Keywords: vaccine acceptance; vaccine hesitancy; vaccine uptake; vaccination

(This special issue belongs to the Section Vaccines and Public Health)

New Approaches to Vaccine Development and Delivery

edited by

Antonio Carlos de Freitas

submission deadline 31 Oct 2025 | 5 articles | Viewed by 5299 | Submission Open

Keywords: vaccines; formulation; vaccine delivery; yeast-based vaccines; surface display; yeast shell; delivery systems; mRNA vaccines; DNA vaccines; subunit vaccine; adjuvant; virus-like particles (VLPs); quality control

(This special issue belongs to the Section Vaccine Advancement, Efficacy and Safety)

Humoral and Cellular Response After Vaccination

edited by Adrian Onu and Iuliana Caras

submission deadline 31 Oct 2025 | 2 articles | Viewed by 5201 | Submission Open

Keywords: vaccine; infectious disease; humoral immunity; cellular immunity; innate immunity; trained immunity; pathogen; virus

(This special issue belongs to the Section Vaccines, Clinical Advancement, and Associated Immunology)

HIV Vaccine Development and Clinical Trails

edited by Massimiliano Bissa

submission deadline 31 Oct 2025 | 2 articles | Viewed by 4834 | Submission Open

Keywords: HIV vaccine; HIV vaccine clinical trial; HIV vaccine adjuvant; correlate of decreased HIV risk; HIV immunogen; broadly neutralizing antibodies

(This special issue belongs to the Section HIV Vaccines)

Vaccine Efficacy and Safety in Transplant Recipients

edited by

Ger Rijkers

submission deadline 31 Oct 2025 | 3 articles | Viewed by 3753 | Submission Open

Keywords: transplant recipients; vaccination; kidney; heart; lung; stem cell transplants; safety; antibody response; efficacy

(This special issue belongs to the Section Vaccine Advancement, Efficacy and Safety)

Personalised Cancer Vaccines

edited by Andrew L. Coveler

submission deadline 31 Oct 2025 | 2 articles | Viewed by 3471 | Submission Open

Keywords: peptide vaccines; mRNA vaccines; DNA vaccines; cancer vaccines

(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)

Novel Viral Vaccine and Molecular Immunology

edited by

Chang Li

submission deadline 31 Oct 2025 | 2 articles | Viewed by 3460 | Submission Open

Keywords: viral infectious diseases; novel vaccines; immune mechanism

(This special issue belongs to the Section Vaccines, Clinical Advancement, and Associated Immunology)

Advances in Allergy, Clinical Immunology, and Vaccines

edited by

Laura Franza

submission deadline 31 Oct 2025 | 1 articles | Viewed by 2918 | Submission Open

Keywords: immunology; allergology; allergy; autoimmunity; biomarkers; environment; pollution

(This special issue belongs to the Section Vaccines, Clinical Advancement, and Associated Immunology)

Infectious Diseases and Immunization in Animals

edited by

Fábio Abade dos Santos

, Ezgi Akdesir and

Jelena Prpić

submission deadline 31 Oct 2025 | 3 articles | Viewed by 2046 | Submission Open

Keywords: animal vaccination; zoonotic diseases; One Health; host– pathogen interaction; veterinary immunology; emerging infectious diseases; antimicrobial resistance; vaccine development

(This special issue belongs to the Section Veterinary Vaccines)

Research in Vaccine Adjuvants: Innovations and Challenges

edited by Haibo Li and

Hongwu Sun

submission deadline 31 Oct 2025 | 1 articles | Viewed by 1662 | Submission Open

Keywords: vaccine adjuvants; immune response enhancement; mucosal vaccine adjuvants; adjuvant safety and efficacy; new adjuvant materials; adjuvant mechanisms of action; adjuvant development challenges

(This special issue belongs to the Section Vaccine Design, Development, and Delivery)

Innovations Advancing Vaccine Preparedness and Response Capabilities to Counter Pandemic Influenza

edited by

Ruben Donis

, Sam Lee,

Christine Oshansky

and

Leah Watson

submission deadline 31 Oct 2025 | 1 articles | Viewed by 1178 | Submission Open

Keywords: influenza vaccines; efficacy; vaccine uptake; rapid manufacturing; vaccine mechanism of action; alternative routes of administration; single-dose regimens

(This special issue belongs to the Section Influenza Virus Vaccines)

Antiviral Immunity and Vaccine Development

edited by

Caijun Sun

and Tao Yu

submission deadline 31 Oct 2025 | 1 articles | Viewed by 987 | Submission Open

Keywords: antiviral innate immunity; adaptive immune responses; viral pathogenesis; immune evasion; host– virus interactions; antiviral vaccine development; vaccine design; novel vaccine platforms; vaccine adjuvants; vaccines and therapeutics

(This special issue belongs to the Section Pathogens-Host Immune Boundaries)

The Development of Recombinant and Subunit Vaccines Against Infectious Diseases

edited by

Abu Salim Mustafa

submission deadline 31 Oct 2025 | Viewed by 603 | Submission Open

Keywords: infectious diseases; vaccines; recombinant antigens; adjuvants

(This special issue belongs to the Section Vaccines against Infectious Diseases)

The Development of Peptide-Based Vaccines

edited by

José Manuel Pérez De La Lastra

and

José de la Fuente

submission deadline 31 Oct 2025 | 1 articles | Viewed by 581 | Submission Open

Keywords: peptide antigens; vaccine design; immunogenicity; epitope mapping; adjuvants; multi-epitope vaccines; personalized peptide vaccines; vaccine delivery systems; computational vaccine design; synthetic peptides

Pandemic Influenza Vaccination

edited by Francisco Nogareda and Shoshanna Goldin

submission deadline 31 Oct 2025 | Viewed by 567 | Submission Open

Keywords: pandemic influenza; vaccines; zoonotic influenza; influenza A/H5; preparedness; response

(This special issue belongs to the Section Influenza Virus Vaccines)

Nanomaterial Application in Vaccines

edited by

Tian Xia

and

Bingbing Sun

submission deadline 31 Oct 2025 | Viewed by 110 | Submission Open

Keywords: nanomaterials; vaccine delivery; immunogenicity enhancement; tolerogenic nanovaccine; nanotechnology; vaccine stability; vaccine design; nanoparticles; immunization strategies; biotechnology in vaccines

(This special issue belongs to the Section Vaccine Design, Development, and Delivery)

Bioengineering in Vaccine Design and Delivery

edited by

Massimo Zollo

submission deadline 1 Nov 2025 | 3 articles | Viewed by 8391 | Submission Open

Keywords: vaccine design; vaccine delivery; vaccine synthesis; vaccine carriers; virus-like particles

(This special issue belongs to the Section Vaccine Design, Development, and Delivery)

Immunobiology of Mycobacterium tuberculosis and Its Implication in Vaccine Design

edited by Tony W. Ng and Steven A. Porcelli

submission deadline 1 Nov 2025 | 2 articles | Viewed by 3806 | Submission Open

Keywords: Mycobacterium tuberculosis; polyfunctional T cells; antibodies; trained immunity; vaccination routes; non-human primates; persisters; auxotrophs; adjuvants

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Molecular Virology and Translational Research in Antiviral Vaccine Development

edited by

Safder Ganaie

submission deadline 20 Nov 2025 | Viewed by 249 | Submission Open

Keywords: molecular virology; antiviral development; vaccine design; host– pathogen interactions; viral entry and replication; immune evasion; structural virology; emerging and re-emerging viruses; zoonotic viruses

COVID Vaccines: Design, Development, and Immune Response Studies: 2nd Edition

edited by

Fabrizio Maggi

and

Licia Bordi

submission deadline 30 Nov 2025 | 21 articles | Viewed by 103014 | Submission Open

Keywords: COVID-19 vaccine; mucosal immunity; immune response; SARS-CoV-2; vaccine design

(This special issue belongs to the Section COVID-19 Vaccines and Vaccination)

Feature Papers of DNA and mRNA Vaccines

edited by

Jorge H. Leitão

submission deadline 30 Nov 2025 | 10 articles | Viewed by 49556 | Submission Open

(This special issue belongs to the Section Nucleic Acid (DNA and mRNA) Vaccines)

Advance Public Health Through Vaccination

edited by

Gianluca Voglino

, Maria Rosaria Gualano,

Giuseppina Lo Moro

and

Erica De Vita

submission deadline 30 Nov 2025 | 15 articles | Viewed by 34038 | Submission Open

Keywords: epidemiology; vaccination strategies; vaccine hesitancy; health equity; vulnerable population

(This special issue belongs to the Section Vaccines and Public Health)

Cancer Vaccines and Immunotherapy: Latest Advances, Limitations and Prospects

edited by

Eyad Elkord

and Afsheen Raza

submission deadline 30 Nov 2025 | 4 articles | Viewed by 10889 | Submission Open

Keywords: cancer; tumor microenvironment; tumor immunotherapy; therapy; cancer vaccines; combination therapy; tumor immune microenvironment; advanced therapies; biomarkers

(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)

Vaccine Efficacy and Safety in Patients with Immune-Mediated Intestinal Diseases

edited by

Adi Lahat

and

Kassem Sharif

submission deadline 30 Nov 2025 | 5 articles | Viewed by 9372 | Submission Open

Keywords: inflammatory bowel disease (IBD); Crohn’ s disease; ulcerative colitis; celiac disease; vaccines; immune-mediated intestinal disease

(This special issue belongs to the Section Vaccine Advancement, Efficacy and Safety)

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