3D Stem Cell Culture—Series 2

Dear Colleagues,

Stem cells have received extensive interest recently because of their unique characteristics and applications in basic and preclinical research. The extent of stem cell use in clinical trials has also increased tremendously owing to their promising therapeutic effects in animal models and in patients. Numerous different stem cells have been isolated from various adult and fetal tissues, and these cells are able to self-renew and differentiate into various end-stage cell types. In order to generate enough stem cells for research and therapies, cells must often be culture-expanded. These cultures often employ traditional 2D techniques that do not necessarily mimic the stem cell environment in vivo well. Therefore, there is great interest in developing 3D culture techniques and characterizing stem cells grown under these conditions to understand basic stem cell biology and also develop effective cells for therapies. These 3D cultures might hold the answers for optimal stem cell preparations for clinical applications.

We invite investigators to contribute reviews and original papers that describe recent findings in the field of 3D stem cell cultures. We especially encourage the submission of research regarding various 3D culture techniques and regenerative medicine approaches using in vitro and in vivo models.

You may choose our Joint Special Issue in Cells.

Dr. Joni H. Ylostalo
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Organoids is an international peer-reviewed open access quarterly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• stem cell
• 3D
• culture condition
• expansion
• growth
• characteristic
• niche
• regenerative medicine
• animal model