Mechanisms and Health Effects of Periodic and Intermittent Fasting

Dear Colleagues,

There is an increasing body of experimental and clinical evidence indicating that fasting and caloric restriction are powerful interventions to prevent, postpone, and treat the globally increasing burden of chronic diseases associated with ageing and metabolic dysfunction. On the other hand, there are worldwide traditions of fasting methods and fasting rituals that are widely known and established in the population. It is time to bring together the knowledge of innovative fasting science and the experience of traditional medicine.

We invite authors worldwide to contribute to this issue focussing on the mechanisms and effects of the full spectrum of existing fasting interventions, including periodic and prolonged fasting, fasting-mimicking diets and intermittent fasting, and fasting-like interventions including fasting mimetics. The Special Issue welcomes original research and reviews, also including observational data, secondary analyses of trials, systematic reviews, and qualitative research elucidating following topics:

• Effects of fasting on clinical outcomes;
• Physiological and metabolic effects including microbiome and metabolomics;
• Fasting and ageing;
• Digital health and fasting;
• Comparative effects of different fasting methods;
• Psychological effects of fasting;
• Fasting and aging;
• Medical effects of fasting;
• Fasting and quality of life;
• Feasibility, adherence, and safety.

Dr. Olga Pivovarova-Ramich
Prof. Dr. Andreas Michalsen
Guest Editors

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