Genomics and Epidemiology of Clinical Microorganisms

Dear Colleagues,

This Special Issue aims to explore the intersection of genomics and epidemiology in understanding the dynamics, evolution, and clinical implications of microorganisms. Contributions to this Special Issue will encompass a broad range of topics, including, but not limited to, the following:

1. Genomic Characterization of Pathogens: Original research focusing on the genomic analysis of clinically relevant microorganisms, elucidating their genetic diversity, virulence factors, and antibiotic resistance profiles.
2. Evolutionary Dynamics: Studies investigating the evolutionary trajectories of pathogens within clinical settings, including the emergence of antimicrobial resistance, genetic adaptation to host environments, and evolutionary drivers shaping microbial populations.
3. Transmission Dynamics and Outbreak Investigations: Research employing genomic epidemiology approaches to track the transmission routes of infectious diseases, investigate outbreak origins, and assess the effectiveness of control measures.
4. Host–Pathogen Interactions: Investigations into the molecular mechanisms underlying host–pathogen interactions, including the identification of microbial virulence determinants, host immune responses, and genetic factors influencing disease susceptibility.
5. Bioinformatics and Computational Tools: Development and application of novel bioinformatics tools, computational algorithms, and genomic surveillance platforms for analyzing large-scale microbial genomic datasets and predicting epidemiological trends.
6. Clinical Implications and Public Health Interventions: Translational research addressing the clinical implications of genomic findings, informing public health policies, and guiding the development of targeted interventions for infectious disease prevention and control.
7. Emerging Technologies and Methodologies: Reviews or perspectives on emerging technologies (e.g., metagenomics and single-cell sequencing) and methodological advancements in genomic and epidemiological research of clinical microorganisms.

This Special Issue seeks to provide a comprehensive platform for researchers, clinicians, and public health professionals to share their latest findings, methodologies, and insights into the genomics and epidemiology of clinical microorganisms, with the ultimate goal of advancing our understanding of infectious diseases and improving patient outcomes.

Dr. Addy Cecilia Helguera-Repetto
Dr. Moises Leon-Juarez
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Microorganisms is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• infectious disease epidemiology
• pathogen genomics
• molecular characterization of microorganisms
• clinical outcomes of infectious diseases
• virulence determinants
• antibiotic resistance
• pathogen gene expression