Special Issues

Life publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Freeze-Dried Plasma for Major Trauma: Trends and Applications submission deadline 20 Sep 2024 | 1 articles | Viewed by 1807 | Submission Open
Keywords: blood products; blood transfusion; coagulation; freeze-dried plasma; fresh frozen plasma; hemorrhage; hemorrhagic shock; hemostatic agent; hemostatic resuscitation; major trauma; massive transfusion; prehospital resuscitation; trauma coagulopathy
(This special issue belongs to the Section Medical Research)
Human Health before, during, and after COVID-19
edited by Alessia Verduri
submission deadline 30 Sep 2024 | 8 articles | Viewed by 11772 | Submission Open
Keywords: COVID-19; telemedicine; pandemic-related anxiety; pandemic-related depression; long COVID; unvaccinated people; new SARS-CoV-2 variants
(This special issue belongs to the Section Epidemiology)
Research Update in Pregnancy Complications submission deadline 30 Sep 2024 | 6 articles | Viewed by 10054 | Submission Open
Keywords: general condition; pregnancy complication; ocular anomaly; neuro-ophthalmological disease; ocular malformations  ; fetal abnormality; infection disease  ; diabetes mellitus; preeclampsia; prenatal diagnosis; genetic testing; amniocentesis
(This special issue belongs to the Section Reproductive and Developmental Biology)
Extremophiles Breakthrough: Hot Topics and Current Issues in Their Isolation, Identification and Biotechnological Applications submission deadline 30 Sep 2024 | 4 articles | Viewed by 5960 | Submission Open
Keywords: astrobiology; biochemistry and molecular biology; biodiversity and ecology; biotechnology; extraterrestrial analogs; extreme environments; extremophiles; genetics; genomics; and proteomics; origin of life; phylogeny and evolution; physiology and metabolism
(This special issue belongs to the Section Microbiology)
New Insights into Allergic Eye Diseases submission deadline 30 Sep 2024 | 2 articles | Viewed by 5419 | Submission Open
Keywords: allergy; IgE; IL-4; IL-5; IL-13; TNF-alpha; mast cells; eosinophils; Th1 cells; Th2 cells; therapeutics; immunopathogenesis; immunopathology; conjunctivitis; keratoconjunctivitis
(This special issue belongs to the Section Medical Research)
The Brain Barriers: Functions and Implications submission deadline 30 Sep 2024 | 2 articles | Viewed by 4059 | Submission Open
Keywords: brain barriers; brain homeostasis; neurodegeneration; neuroinflammation; brain drug delivery
(This special issue belongs to the Section Physiology and Pathology)
Kidney Transplantation: What’s Hot and What’s New
edited by and Caterina Di Bella
submission deadline 30 Sep 2024 | 3 articles | Viewed by 3066 | Submission Open
Keywords: kidney transplantation; immunosuppression; graft quality; machine perfusion (MP); living donor kidney transplantation
(This special issue belongs to the Section Medical Research)
New Advances in Neuroimaging and Brain Functions: 2nd Edition submission deadline 30 Sep 2024 | 1 articles | Viewed by 2990 | Submission Open
Keywords: neuroimaging; brain functions; neurological diseases; humanities and social sciences; noninvasive methods; AI deep learning
(This special issue belongs to the Section Radiobiology and Nuclear Medicine)
Advances in Substance Abuse and Addiction
edited by , and Chieh-Liang Huang
submission deadline 30 Sep 2024 | 2 articles | Viewed by 1333 | Submission Open
Keywords: addiction medicine; opioid pharmacology; substance abuse; addictive disorders intervention
(This special issue belongs to the Section Pharmaceutical Science)
Alternative Pharmacological Approaches for Septic Shock Management: Beyond Traditional Amine-Based Therapies
edited by Guglielmo Consales and
submission deadline 30 Sep 2024 | 1 articles | Viewed by 815 | Submission Open
Keywords: decatecholaminisation; non-amine-based therapy; beta blockers; hormone replacement; levosimendan; Angiotensin II; sepsis; septic shock; septic cardiomyopathy
(This special issue belongs to the Section Pharmaceutical Science)
Alzheimer’s Disease: Recent Developments in Pathogenesis, Diagnosis, and Therapy submission deadline 30 Sep 2024 | Viewed by 218 | Submission Open
Keywords: Alzheimer’ s disease; biomarkers; epigenetics; genetics; genomics; immune mediators; neurodegeneration; neuroinflammation; proteomics; risk factors; therapy; transcriptomics
(This special issue belongs to the Section Physiology and Pathology)
Clinicopathology and Diagnosis of Gastric Cancer: New Advances and Perspectives
edited by Daniela Cornelia Lazar
submission deadline 30 Sep 2024 | Viewed by 206 | Submission Open
Keywords: carcinogenesis; helicobacter pylori; biomarkers; chemotherapy; immunotherapy; molecular pathways; early detection; epidemiology; genomic profiling
(This special issue belongs to the Section Medical Research)
Pathology, Treatment, and Rehabilitation of Movement Disorders
edited by
submission deadline 30 Sep 2024 | Viewed by 186 | Submission Open
Keywords: neurorehabilitation; outcome measures  ; functional assessment  ; therapies
(This special issue belongs to the Section Physiology and Pathology)
Molecular Mechanisms of Preeclampsia
edited by Feng Li
submission deadline 30 Sep 2024 | Viewed by 152 | Submission Open
Keywords: preeclampsia; hypertension; proteinuria; placenta; fetal growth restriction; pregnancy com-plications; implantation
(This special issue belongs to the Section Reproductive and Developmental Biology)
Green Medicine: Unraveling the Medicinal Effects of Plant Extracts and Functional Foods submission deadline 22 Oct 2024 | 2 articles | Viewed by 1982 | Submission Open
Keywords: plant extracts; phytochemicals; inflammation; obesity; liver disease; oxidative stress; antioxidants; diabetes; skin damage; aging
(This special issue belongs to the Section Pharmaceutical Science)
Virus Genomics and Diversity
edited by Temitope O. C. Faleye, and
submission deadline 22 Oct 2024 | Viewed by 215 | Submission Open
Keywords: genomics; diversity; virus evolution; virus detection; genome sequencing; DNA sequencing
(This special issue belongs to the Section Microbiology)
Eye Diseases: Diagnosis and Treatment, 2nd Edition
edited by and Laura De Diego-García
submission deadline 30 Oct 2024 | 8 articles | Viewed by 9169 | Submission Open
Keywords: ocular treatment; ocular diseases; retina; anterior eye; posterior eye; ocular biomarkers
(This special issue belongs to the Section Medical Research)
The Role of Renewable Resources for Ecology and Human Health: 2nd Edition
edited by
submission deadline 30 Oct 2024 | 4 articles | Viewed by 7204 | Submission Open
Keywords: residual products; waste products; multidrug resistance; cancer; natural compounds and antioxidants; anti-inflammatory effect; antiviral properties; antifungal activity
Prostate Cancer: 3rd Edition submission deadline 30 Oct 2024 | 5 articles | Viewed by 5872 | Submission Open
Keywords: incidence; mortality; diagnosis; histopathology; imaging; treatment; prognosis; case report; animals; humans; modelling
(This special issue belongs to the Section Medical Research)
Advances in Artificial Intelligence for Medical Image Analysis
edited by
submission deadline 30 Oct 2024 | 4 articles | Viewed by 5259 | Submission Open
Keywords: artificial intelligence; medical imaging; deep learning for medical imaging; histopathological image analysis; medical diagnosis; visualization in biomedical imaging; magnetic resonance imaging (MRI); X-ray computed tomography (CT); positron emission tomography (PET); medical image fusion
(This special issue belongs to the Section Radiobiology and Nuclear Medicine)
Recent Advances in Functional Genomics
edited by Katerina R. Katsani and
submission deadline 30 Oct 2024 | 1 articles | Viewed by 1868 | Submission Open
Keywords: chromatin profiling; CRISPR screens; crop genomics; epigenome editing; epigenomics; interactomes; metagenomics; pharmacogenomics; phenomics
(This special issue belongs to the Section Genetics and Genomics)
New Insights into Breast Cancer: Current Controversies and Future Perspectives
edited by , Angela Bucaro and Flavia de Lauretis
submission deadline 30 Oct 2024 | Viewed by 238 | Submission Open
Keywords: breast cancer treatment; oncoplastic surgery; conservative mastectomy; breast reconstruction; sentinel node biopsy; chemotherapy; radiotherapy; integrated therapies
(This special issue belongs to the Section Medical Research)
Impact of Circulating Ketones on Physiology
edited by Maleah Winkler
submission deadline 30 Oct 2024 | Viewed by 215 | Submission Open
Keywords: ketones; ketone supplementation; beta-hydroxybutyrate; ketogenic diet; fasting
(This special issue belongs to the Section Physiology and Pathology)
Advances in the Treatment of Pulmonary Hypertension and Pulmonary Embolism submission deadline 30 Oct 2024 | Viewed by 164 | Submission Open
Keywords: pulmonary hypertension; pulmonary embolism; therapy; cardiac imaging; artificial intelligence
(This special issue belongs to the Section Medical Research)
Advances in Research in Biocatalysis: 2nd Edition
edited by and
submission deadline 30 Oct 2024 | Viewed by 154 | Submission Open
Keywords: biochemical; biomedical; biomaterials; biocatalysis; biodegradation; biofuels; bioplastics; directed evolution of enzymes; environmental remediation
(This special issue belongs to the Section Biochemistry, Biophysics and Computational Biology)
Clinical Manifestations and Treatment of Autoimmune Diseases submission deadline 31 Oct 2024 | 11 articles | Viewed by 16688 | Submission Open
Keywords: autoimmunity; immunobiology; vaccine; leucocytes; immune system
(This special issue belongs to the Section Medical Research)
Natural Additives to Promote Organic and Sustainable Poultry Production submission deadline 31 Oct 2024 | 6 articles | Viewed by 13399 | Submission Open
Keywords: poultry; sustainable intensification; product quality; physiological responses; nutrient digestibility; growth performance; carcass performance; Gut microbiota
(This special issue belongs to the Section Animal Science)
Mechanism, Diagnostic and Therapeutic Novelties in Dermatology: 2nd Edition submission deadline 31 Oct 2024 | 9 articles | Viewed by 13145 | Submission Open
Keywords: physiopathology; skin sonography; dermoscopy; innovation; confocal microscopy; biological treatment; psoriasis; atopic dermatitis; immune-mediated diseases; urticaria; laser CO2
(This special issue belongs to the Section Medical Research)
Current Problems and New Horizons in Headache Clinical Practice
edited by , and Muneto Tatsumoto
submission deadline 31 Oct 2024 | 5 articles | Viewed by 7411 | Submission Open
(This special issue belongs to the Section Medical Research)
Trauma and Emergency: Beyond Damage Control Surgery: 2nd Edition
edited by , and Matteo Zanchetta
submission deadline 31 Oct 2024 | 4 articles | Viewed by 4572 | Submission Open
Keywords: trauma surgery; emergency surgery; DAMP; damage-associated molecular pattern; post-injury inflammation; hemorrhage; transplant surgery; robotic surgery; danger model; PRR; pattern recognition receptors
(This special issue belongs to the Section Medical Research)
New Horizons of Adipose Tissue Disorders: From Hormonal Issues to Loose Connective Disease submission deadline 31 Oct 2024 | 2 articles | Viewed by 4517 | Submission Open
Keywords: adipose tissue; lipedema; lymphedema; obesity; matrix; vascular and lymphatic disorder; connective tissue diseases; dysbiosis; inflammation; pain
(This special issue belongs to the Section Physiology and Pathology)
Personalized Prevention and Treatment in Endocrinology, Diabetes and Metabolic Diseases
edited by Grigorios Panagiotou
submission deadline 31 Oct 2024 | 3 articles | Viewed by 3174 | Submission Open
Keywords: personalized medicine; precision prevention; multi-omics; obesity; diabetes and endocrinology
(This special issue belongs to the Section Medical Research)
Veterinary Pathology and Veterinary Anatomy: 2nd Edition submission deadline 31 Oct 2024 | 4 articles | Viewed by 3108 | Submission Open
Keywords: veterinary pathology; veterinary anatomy; SARS-CoV2 pandemic; climate change; environmental pollution; diagnosis and treatment of animal diseases; computer modeling of pathological processes
(This special issue belongs to the Section Animal Science)
Advanced Endoscopy in the Treatment of Complications after Gastrointestinal Surgery submission deadline 31 Oct 2024 | 3 articles | Viewed by 2469 | Submission Open
Keywords: advanced endoscopy; complications; surgery; anastomotic leak
(This special issue belongs to the Section Medical Research)
AI and Precision Medicine: Using Machine Learning for Disease Diagnosis and Prediction
edited by and Sarantis Chlamydas
submission deadline 31 Oct 2024 | 2 articles | Viewed by 1879 | Submission Open
Keywords: AI; machine learning; cancer; cardiovascular diseases; neurological disorders; genomics; diagnosis; prognosis; treatment response; disease-risk prediction
(This special issue belongs to the Section Medical Research)
Human Infertility and Reproductive Endocrinology: 2nd Edition
edited by
submission deadline 31 Oct 2024 | 1 articles | Viewed by 1165 | Submission Open
Keywords: infertility; reproduction; reproductive endocrinology; male infertility; female infertility
(This special issue belongs to the Section Reproductive and Developmental Biology)
Nutritional Supplements and Cardiovascular Function in Athletes and Sedentary People submission deadline 31 Oct 2024 | 1 articles | Viewed by 873 | Submission Open
Keywords: athletes; sedentary; eating habits; nutrition; endothelium; microcirculation; nutritional supplements; oxidative stress; antioxidants; NRF2-signalling pathway; functional food; cardiovascular function; prevention
(This special issue belongs to the Section Medical Research)
DNA Damage, Repair and Mutagenesis submission deadline 31 Oct 2024 | Viewed by 320 | Submission Open
Keywords: genomics; epigenomics; genome instability; cancer; neurodegeneration; ageing; chemotherapy; replication; transcription; mutational signatures
(This special issue belongs to the Section Genetics and Genomics)
Role of Mitochondria in the Pathophysiology of Cardiovascular Diseases
edited by Yuriana Oropeza-Almazán and Héctor Chapoy-Villanueva
submission deadline 31 Oct 2024 | Viewed by 247 | Submission Open
Keywords: cardiovascular diseases (CVDs); mitochondria; mitochondrial dysfunction; ATP production; mitochondrial fission; mitochondrial fusion; electron transport chain; oxidative phosphorylation; mitophagy; cardiac hypertrophy; myocardial infarction; IR injury; mitochondrial ROS; ROS signaling; ion homeostasis; cardiac arrhythmias
(This special issue belongs to the Section Physiology and Pathology)
Nutrition and Chronic Disease
edited by and Yinhua Zhu
submission deadline 31 Oct 2024 | Viewed by 236 | Submission Open
Keywords: chronic disease; nutritional intervention; aging; risk factors; metabolism; inflammation; cell signaling; therapeutic target; mechanisms of action; drug discovery
(This special issue belongs to the Section Physiology and Pathology)
Current and Future Perspectives of Artificial Intelligence in Medicine
edited by Giuseppe Consorti, Lisa Catarzi and
submission deadline 31 Oct 2024 | Viewed by 231 | Submission Open
Keywords: artificial intelligence; machine learning; deep learning; medical practices; artificial neural network; computational health informatics; predictive analytics in healthcare; ethics in AI for medical applications
(This special issue belongs to the Section Medical Research)
Mechanism, Diagnosis, and Treatment of Aortic Diseases: 2nd Edition
edited by
submission deadline 31 Oct 2024 | Viewed by 230 | Submission Open
Keywords: aorta; aortic disease; aortic aneurysm; aortic dissection; penetrating aortic ulcer; aortic stenosis; arteritis; pathomechanism; diagnosis; pharmacological therapy; invasive therapy; endovascular therapy; open surgery
(This special issue belongs to the Section Medical Research)
Feature Papers in Periprosthetic Joint Infection
edited by Andrea Sambri and
submission deadline 31 Oct 2024 | Viewed by 155 | Submission Open
Keywords: orthoplastic approach; artificial intelligence; diagnosis and management of PJI; antibiotic therapy in prosthetic joint infections
(This special issue belongs to the Section Medical Research)
Advances and Applications of Neuroimaging in Brain Disorder
edited by Julio Plata-Bello
submission deadline 31 Oct 2024 | Viewed by 142 | Submission Open
Keywords: neuroimaging; magnetic resonance imaging; positron emission tomography; near infrared spectroscopy; brain; dementia; schizophrenia; depression; brain tumors; multiple sclerosis; autism
(This special issue belongs to the Section Radiobiology and Nuclear Medicine)
Nanomedicine as a Path to Counteract Infectious Disease submission deadline 31 Oct 2024 | Viewed by 122 | Submission Open
Keywords: infectious diseases; nanomedicine; nanotechnology; nanoparticles; biomaterials; microbiota; biofilm treatment and/or eradication; antimicrobial activity; novel antimicrobial drugs
(This special issue belongs to the Section Medical Research)
Current Approaches and Future Directions in the Treatment of Gynecologic Tumors: Molecular Biology, Diagnostic Advancements and Targeted Therapeutic Strategies submission deadline 1 Nov 2024 | Viewed by 159 | Submission Open
Keywords: gynecologic tumors; cervical cancer; ovarian cancer; endometrial cancer; vulvar cancer; vaginal cancer; gestational trophoblastic disease; molecular mechanisms; diagnostic advancements; novel therapies
(This special issue belongs to the Section Physiology and Pathology)
Obstetrics and Gynecology Medicine: Go From Bench to Bedside submission deadline 8 Nov 2024 | 12 articles | Viewed by 15965 | Submission Open
Keywords: obstetrics; gynecology; translational research; translational medicine
(This special issue belongs to the Section Physiology and Pathology)
Emerging Knowledge on Human Immunodeficiency Virus submission deadline 18 Nov 2024 | Viewed by 290 | Submission Open
Keywords: HIV; antiretroviral treatment; long-acting ART; pre-exposure prophylaxis; HIV surveillance; antiretroviral resistance; primary resistance; HIV epidemiology; special populations; cascade of care; HIV diagnosis
(This special issue belongs to the Section Medical Research)
Focus on Exercise Physiology and Sports Performance
edited by
submission deadline 19 Nov 2024 | 9 articles | Viewed by 26098 | Submission Open
Keywords: exercise; physical activity; nutrition; exercise physiology; sports performance
(This special issue belongs to the Section Physiology and Pathology)
Obstructive Sleep Apnea: Current Knowledge and Future Perspectives submission deadline 21 Nov 2024 | 8 articles | Viewed by 17502 | Submission Open
Keywords: sleep apnoea syndrome— clinical and pathophysiological phenotypes; diagnosis and comorbidities; biomarkers; personalized treatment; predictors of outcomes; prognosis and mortality
(This special issue belongs to the Section Physiology and Pathology)
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