New Advances in Joints Osteoarthritis

Dear Colleagues,

Osteoarthritis (OA) is the most common joint disease, affecting an estimated more than 240 million people worldwide, including an estimated more than 32 million in the US. Osteoarthritis is the most frequent reason for activity limitation in adults. Therapeutic approaches predominantly addressed symptoms and tried to modify/improve structural features of affected joint tissues. The development of novel therapeutic approaches targeting the osteoarthritic degradative and inflammatory processes in cartilage, synovium, or bone requires a deep understanding of the disease status of these joint tissues at the time of the intervention. With the growth of surgical skills in hip and knee arthroscopy, cartilage restoration techniques are evolving in a fast and exponential manner. Biological and surgical treatments have been proposed to treat these pathologies: biological treatments include platelet-rich plasma, stem cells or bone marrow aspirate concentration, hyaluronic acid and others. However, for many people, joint replacement surgery has been the only option available to repair joints damaged by osteoarthritis. The developments in hip and knee arthroplasty over recent years have aimed to improve outcomes, reduce complications and improve implant survival. Notable developments have included ceramic hip resurfacing, mini hip stems, cementless knee replacement and the wider adoption of the dual mobility articulation for hip arthroplasty. This Special Issue is aimed at providing selected contributions on new advances in Knee and Hip Osteoarthritis’. Potential topics include, but are not limited to:

• Potential new radiological classification system of OA
• Cell-based therapies for low and intermediate grade of OA
• Effectiveness of infiltrative therapy with different type of hyaluronic acid
• Osteoarthritis and sports
• New challenge in prosthetic design for the treatment of knee OA
• New challenge in prosthetic design for the treatment of hip OA
• Tribology in TKA and THA
• Exeperience with Robotic assisted surgery.

Dr. Eugenio Jannelli
Dr. Alberto Castelli
Prof. Dr. Federico A. Grassi
Guest Editors

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• knee
• hip
• arthroplasty
• regenerative medicine
• TKA
• THA
• robotic assisted surgery