Special Issues

Cells publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic. The journal’s Editor-in-Chief and/or designated EBM will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Novel Mechanisms of Gene Regulation in Cardiac Development and Congenital Heart Defects
edited by
submission deadline 15 Aug 2024 | Viewed by 113 | Submission Open
Keywords: long noncoding RNA; epigenetic regulation; whole-genome sequencing; cardiomyocyte signaling; cardiovascular development  ; congenital heart defects
(This special issue belongs to the Section Cells of the Cardiovascular System)
The Interplay of G-Protein-Coupled Receptor Signaling between Humans and Diseases
edited by Victor Garcia
submission deadline 15 Aug 2024 | Viewed by 71 | Submission Open
Keywords: G-proteins; G-protein-coupled receptors; G-protein-independent signaling; cAMP signals
Brain Tumors: From Neuropathology to Molecular Biology
edited by , Marialaura Del Basso De Caro and
submission deadline 20 Aug 2024 | Viewed by 227 | Submission Open
Keywords: brain tumor pathology; neuro-oncology; molecular biology; immunohistochemistry; histopathology
(This special issue belongs to the Section Cellular Pathology)
Molecular and Cellular Mechanisms on Plant Polyphenols submission deadline 20 Aug 2024 | Viewed by 186 | Submission Open
Keywords: natural polyphenols; cell homeostasis; anti-oxidant; anti-inflammatory; health effects
(This special issue belongs to the Section Plant, Algae and Fungi Cell Biology)
Kidney Disease Models, Cellular Mechanism and Potential Treatment
edited by
submission deadline 20 Aug 2024 | Viewed by 109 | Submission Open
Keywords: kidney disease; signaling pathways; therapy; biomarker; prevention
(This special issue belongs to the Section Tissues and Organs)
Molecular Mechanism of Bone Disease submission deadline 20 Aug 2024 | Viewed by 93 | Submission Open
Keywords: bone; mesenchymal stem cells; transcription factors; bone rare diseases; skeletal degenerative diseases
Regulation of Fibroblasts and Fibrosis in Cardiovascular Disease
edited by
submission deadline 20 Aug 2024 | Viewed by 80 | Submission Open
Keywords: fibrosis; fibroblasts; cardiovascular; inflammation; extracellular matrix; collagen
(This special issue belongs to the Section Cells of the Cardiovascular System)
Inflammation in Target Organs
edited by
submission deadline 29 Aug 2024 | 1 articles | Viewed by 1551 | Submission Open
Keywords: inflammation; fibrosis; cardio-renal; vascular; liver; brain
(This special issue belongs to the Section Cellular Immunology)
Fat Is a Matter? The Implication of Adipose Tissue in Cardiovascular Health and Disease
edited by
submission deadline 30 Aug 2024 | 3 articles | Viewed by 8382 | Submission Open
Keywords: adipose tissue; adipocyte; cardiovascular disease; metabolic disease; energy homeostasis
(This special issue belongs to the Section Cellular Metabolism)
Regulatory T Cells and Autoimmunity
edited by Fan Pan
submission deadline 30 Aug 2024 | 1 articles | Viewed by 1634 | Submission Open
Keywords: regulatory T cells; immune tolerance; Foxp3; autoimmune disease (AD); immunotherapy
(This special issue belongs to the Section Cellular Immunology)
Pluripotent Stem Cells: Current Applications and Future Directions
edited by
submission deadline 30 Aug 2024 | 1 articles | Viewed by 975 | Submission Open
Keywords: induced pluripotent stem cells; organoids; reprogramming; differentiation; spheroids; cortical organoids; intestinal organoids; kidney organoids; cardiomyocytes; astrocytes; microglia; personalized medicine; drug screening; disease modeling
(This special issue belongs to the Section Stem Cells)
Focus on Redox Signaling submission deadline 30 Aug 2024 | Viewed by 257 | Submission Open
Keywords: redox signaling; oxidative stress; reactive oxygen species (ROS); reactive molecules; cellular signaling; human diseases
(This special issue belongs to the Section Cell Signaling)
The Molecular Research on Incretins and Diabetic Comorbidities submission deadline 30 Aug 2024 | Viewed by 201 | Submission Open
Keywords: GIP; GLP-1; differentiation; atherosclerosis; intestine; animal models; drug screening
(This special issue belongs to the Section Cellular Metabolism)
Multifaceted Roles of Mesenchymal Stem Cells in Health and Disease
edited by and Bartłomiej Łukaszuk
submission deadline 30 Aug 2024 | Viewed by 181 | Submission Open
Keywords: diabetes mellitus; dyslipidemia; insulin resistance; metabolic syndrome; mesenchymal stem cells; obesity
(This special issue belongs to the Section Stem Cells)
The Cell Biology of Heart Disease
edited by Rajeshwary Ghosh and
submission deadline 30 Aug 2024 | Viewed by 151 | Submission Open
Keywords: cardiomyopathy; endothelial dysfunction; cellular senescence; fibrosis; myocardial infarction; inflammation; mitochondrial dysfunction; CAD; arrhythmia; heart failure
(This special issue belongs to the Section Cells of the Cardiovascular System)
Ion Channels in Pain: Mechanisms and Therapeutics
edited by Hongwei Yu, Michelino Puopolo and Seung Min Shin
submission deadline 30 Aug 2024 | Viewed by 115 | Submission Open
Keywords: chronic pain; sensory neurons; ion channels; pain mechanisms; pain therapeutics
(This special issue belongs to the Section Cells of the Nervous System)
Extracellular Vesicles as Biomarkers for Human Disease
edited by
submission deadline 30 Aug 2024 | Viewed by 77 | Submission Open
Keywords: extracellular vesicles; exosomes; biomarkers; human diseases; diagnostic applications; prognostic indicators; EV subtypes; isolation techniques
(This special issue belongs to the Section Intracellular and Plasma Membranes)
Cell Death Mechanisms and Therapeutic Opportunities in Glioblastoma
edited by
submission deadline 31 Aug 2024 | 15 articles | Viewed by 27211 | Submission Open
Keywords: apoptosis; autophagy; cell death mechanisms; cell signaling; glioblastoma; therapeutic opportunities
(This special issue belongs to the Section Cells of the Nervous System)
Proteomic Applications in Ageing and Neurodegenerative Conditions submission deadline 31 Aug 2024 | 4 articles | Viewed by 10811 | Submission Open
(This special issue belongs to the Section Cell Methods)
The Therapeutic Role of Extracellular Vesicles in COVID-19: Therapeutic and Preventive Mechanism
edited by
submission deadline 31 Aug 2024 | 3 articles | Viewed by 9626 | Submission Open
Keywords: extracellular vesicles; severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and coronavirus disease 2019 (COVID-19); EV-associated COVID-19 pathogenesis; therapeutic intervention; treatment
(This special issue belongs to the Section Cell Microenvironment)
CRISPR-Based Genome Editing in Translational Research—Second Edition
edited by Jifeng Zhang, and
submission deadline 31 Aug 2024 | 4 articles | Viewed by 7648 | Submission Open
(This special issue belongs to the Section Cell and Gene Therapy)
Novel Insights into Molecular Mechanisms and Therapy of Asthma
edited by
submission deadline 31 Aug 2024 | 3 articles | Viewed by 5212 | Submission Open
(This special issue belongs to the Section Cellular Pathology)
Tuberculosis: From Pathogenesis to Targeted Therapies submission deadline 31 Aug 2024 | 3 articles | Viewed by 4840 | Submission Open
Keywords: tuberculosis; therapy; granuloma; antibiotics; host-directed
(This special issue belongs to the Section Cellular Pathology)
The Emerging Role of Astrocytes in Health and Neurological Diseases
edited by
submission deadline 31 Aug 2024 | 3 articles | Viewed by 4011 | Submission Open
Keywords: astrocyte network; gliotransmitters; astrocytes in learning and memory; astrocytes and the blood– brain barrier; astrocyte pathologies
(This special issue belongs to the Section Cells of the Nervous System)
The Ubiquitin–Proteasome System (UPS): Signaling Processes and Targeted Protein Degradation
edited by
submission deadline 31 Aug 2024 | 2 articles | Viewed by 3537 | Submission Open
Keywords: ubiquitin– proteasome system; ubiquitin ligases; targeted protein degradation; bispecific chimeras; novel chimera approaches
(This special issue belongs to the Section Cell Signaling)
The Pivotal Role of Tumor Stem Cells in Glioblastoma
edited by and Silvano J. Santini
submission deadline 31 Aug 2024 | 2 articles | Viewed by 2289 | Submission Open
Keywords: glioblastoma stem cells; resistance; cancer therapy; signaling pathways; tumor microenvironment
(This special issue belongs to the Section Stem Cells)
Oral Diseases: Biological and Molecular Pathogenesis
edited by
submission deadline 31 Aug 2024 | 2 articles | Viewed by 1812 | Submission Open
Keywords: pathogenesis; immunohistochemical and molecular alteration; oral diseases
(This special issue belongs to the Section Cellular Pathology)
Cell Adhesion/Migration in Tumor Metastasis
edited by
submission deadline 31 Aug 2024 | 1 articles | Viewed by 1773 | Submission Open
Keywords: cell adhesion; invasion; migration; extracellular matrix
(This special issue belongs to the Section Cell Motility and Adhesion)
New Strategies in Therapeutic Targets of Epilepsy
edited by Cameron S. Metcalf
submission deadline 31 Aug 2024 | 1 articles | Viewed by 1570 | Submission Open
Keywords: drug development; animal models; epilepsy; seizure; rare epilepsy; traumatic brain injury; epileptogenesis; disease modification; drug discovery
Skeletal Muscle Atrophy in Health and Disease: From Molecular Mechanisms to Therapeutic Opportunities submission deadline 31 Aug 2024 | 1 articles | Viewed by 1199 | Submission Open
Keywords: muscle atrophy; inactivity; ageing; sarcopenia; neuromuscular disorders
(This special issue belongs to the Section Cellular Pathology)
New Trends and Advances in Diagnosis and Prognosis of Head and Neck Cancer from Carcinogenesis to Future Molecular Targeted Therapies II submission deadline 31 Aug 2024 | 1 articles | Viewed by 1047 | Submission Open
Keywords: head and neck cancer; oral cancer; biomarker; prognosis; carcinogenesis; oral premalignant lesions; cancer stem cells; signaling pathways; molecular targeted therapy
(This special issue belongs to the Section Cellular Pathology)
State of the Art in Stem Cell Culture for Regenerative Medicine submission deadline 31 Aug 2024 | 1 articles | Viewed by 1026 | Submission Open
Keywords: stem cells; cell culture techniques; regenerative medicine; tissue engineering
(This special issue belongs to the Section Stem Cells)
Mechanisms of Respiratory Diseases submission deadline 31 Aug 2024 | 1 articles | Viewed by 907 | Submission Open
Keywords: cell death/stress; DNA/RNA sensor; cGAS/STING; inflammasome; microbiome; FMT or transfer of bacteria; metabolite; viral infection; emphysema; progressive fibrosis; innate immune response; defined inhibitors
Cellular and Clinical Mechanisms of Obesity and Diabetes and Their Complications submission deadline 31 Aug 2024 | 1 articles | Viewed by 868 | Submission Open
Keywords: obesity; type 1 diabetes; type 2 diabetes; metabolic disorders; complications; signaling pathways; pathophysiology; insulin; β -cell
(This special issue belongs to the Section Cellular Pathology)
Identifying Molecular or Cellular Level Pathomechanisms for Possible Therapeutic/Neuroprotective Interventions in Traumatic Brain Injury
edited by Krisztina Amrein and
submission deadline 31 Aug 2024 | 1 articles | Viewed by 777 | Submission Open
Keywords: traumatic brain injury; head injury; clinical study; experimental model; neuroprotective intervention; therapy; pathomechanism; molecular; cellular
(This special issue belongs to the Section Cellular Pathology)
Apoptosis in Cancers
edited by
submission deadline 31 Aug 2024 | 1 articles | Viewed by 555 | Submission Open
Keywords: apoptosis; cancer; resistance; caspase; bcl-2; p53; death receptor; small molecules; pharmacological targeting
Molecular Mechanisms and Clinical Treatments of Neurofibromatosis Type 1 Related Tumors
edited by and Federica Chiara
submission deadline 31 Aug 2024 | Viewed by 316 | Submission Open
Keywords: neurofibromatosis type 1; rare tumors; genetic syndrome; plexiform neurofibroma; malignant peripheral nerve sheath tumor; tumor suppressor; Ras signalling; tumor microenvironment; anti-neoplastic therapy; neoplastic transformation
(This special issue belongs to the Section Cells of the Nervous System)
Antiphospholipid Syndrome: Molecular Mechanisms and Novel Therapies
edited by and Simona Truglia
submission deadline 31 Aug 2024 | Viewed by 279 | Submission Open
Keywords: antiphospholipid syndrome; pathophysiology; management; treatment; antiphospholipid antibodies; molecular mechanisms; new biomarkers; diagnostic tests
(This special issue belongs to the Section Cellular Pathology)
Application of Gel-Based Proteomic Techniques: Unveiling the Molecular Tapestry
edited by Gagandeep Singh, Sandeep Kumar and Navleen Kaur
submission deadline 31 Aug 2024 | Viewed by 244 | Submission Open
(This special issue belongs to the Section Cellular Pathology)
Extracellular Vesicles in Tissue Repair and Regeneration
edited by
submission deadline 31 Aug 2024 | Viewed by 228 | Submission Open
Keywords: stem cells; extracellular vesicles; exosomes; regeneration; tissue repair; cell signaling
(This special issue belongs to the Section Tissues and Organs)
Stem Cell Therapy for Autoimmune Diseases—Second Edition submission deadline 31 Aug 2024 | Viewed by 187 | Submission Open
Keywords: autoimmune disease; stem cell therapy; hematopoietic stem cells; mesenchymal stem cells; MSC-derived secretome
Pulmonary Vascular Diseases in Extreme Environments: What Is Our Current Knowledge? submission deadline 31 Aug 2024 | Viewed by 158 | Submission Open
Keywords: pulmonary vascular diseases; pulmonary hypertension; pulmonary vascular vasoconstriction; pulmonary vascular remodeling; high altitude; hypoxia; cold exposure; cold environment; cellular and molecular mechanisms
(This special issue belongs to the Section Cells of the Cardiovascular System)
Ovary and Brain—Series II
edited by Ilana I. Chefetz
submission deadline 31 Aug 2024 | Viewed by 142 | Submission Open
Keywords: ovary  ; ovary-brain communication  ; cancer  ; neurodegenerative diseases  ; mitochondrial dysfunction  ; cancer therapy  ; neurodegeneration mechanisms  ; therapeutic interventions  ; signaling pathways  ; molecular targets  ; precision medicine  ; biomarkers  ; cellular dynamics  ; translational research  ; addiction  ; reproductive health
Human Inborn Errors of Immunity
edited by
submission deadline 31 Aug 2024 | Viewed by 142 | Submission Open
Keywords: inborn errors of immunity (IEI); primary immune deficiencies (PID); human; immune cells; susceptibility to infections; pathogens; autoimmunity; autoinflammation; allergy; malignancies; gene therapy; cellular therapy; hematopoietic stem cell transplantation (HSCT); pharmacotherapy
(This special issue belongs to the Section Cellular Immunology)
Biomarkers for Therapeutic Advances in Breast Cancer submission deadline 31 Aug 2024 | Viewed by 138 | Submission Open
Keywords: breast cancer; biomarkers; therapeutic strategies; targeted therapy; breast cancer management
(This special issue belongs to the Section Cellular Pathology)
Extracellular Vesicles-Related Cellular Events in Neuronal Biology: Regulated Cell Death, Autophagy, Unfolded Protein Response, and Stress-Related Pathways submission deadline 31 Aug 2024 | Viewed by 135 | Submission Open
Keywords: extracellular vesicles; exosomes; regulated (or programmed) cell death; autophagy; homeostasis; stress; unfolded protein response (UPR) signaling pathways; endoplasmic reticulum (ER) stress; protein quality control (PQC); mitochondria; neuron; neurogenesis; neurodegeneration; brain
(This special issue belongs to the Section Autophagy)
Understanding the Host/Microbe–Microbe Interactions in Human Diseases: From Imaging Technologies to Multi-omics Approaches
edited by
submission deadline 31 Aug 2024 | Viewed by 135 | Submission Open
Keywords: optical imaging; host/microbe– microbe interactions; microbial communities
(This special issue belongs to the Section Cell Methods)
Mitochondrial Metabolism in Skeletal Muscle
edited by
submission deadline 31 Aug 2024 | Viewed by 128 | Submission Open
Keywords: skeletal muscle; mitochondria; mitochondrial dysfunction; mitochondrial diseases; mitochondrial biogenesis
Gene Therapy for Rare Diseases
edited by
submission deadline 31 Aug 2024 | Viewed by 124 | Submission Open
Keywords: gene therapy; gene editing; rare diseases; CRISPR; viral vectors; base editing; prime editing
(This special issue belongs to the Section Cell Nuclei: Function, Transport and Receptors)
Advances and Breakthroughs in Stem Cell Research submission deadline 31 Aug 2024 | Viewed by 124 | Submission Open
Keywords: stem cell; induced pluripotent stem cell; iPSC; hematopoietic stem cell
(This special issue belongs to the Section Stem Cells)
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