Special Issues

Biomolecules publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Neurological Disorders: From Molecular Mechanisms to Therapy Strategies submission deadline 30 Sep 2024 | 8 articles | Viewed by 23367 | Submission Open
Keywords: neurodegeneration; neuroprotection; novel therapies; natural molecules
(This special issue belongs to the Section Molecular Biology)
Artificial Intelligence (AI) in Biomedicine submission deadline 30 Sep 2024 | 10 articles | Viewed by 21212 | Submission Open
(This special issue belongs to the Section Bioinformatics and Systems Biology)
Effects of Weightlessness on Molecular Changes in Cellular Organisms, Animals and Plants
edited by
submission deadline 30 Sep 2024 | 8 articles | Viewed by 16708 | Submission Open
Keywords: cells; humans; animals; plants; microorganisms; microgravity; weightlessness; cancer research; tissue engineering; space-related health problems
(This special issue belongs to the Section Cellular Biochemistry)
Nutrition, Metabolism, and Obesity: Novel Strategies and Molecular Mechanisms—Future Perspectives submission deadline 30 Sep 2024 | 7 articles | Viewed by 13974 | Submission Open
Keywords: diet; nutrients; obesity; inflammation; fat; glucose intolerance; insulin resistance; fatty liver disease; metabolic syndrome
(This special issue belongs to the Section Molecular Medicine)
Novel Molecules for Cancer Treatment (2nd Edition) submission deadline 30 Sep 2024 | 6 articles | Viewed by 13795 | Submission Open
Keywords: cancer; small molecules; antibody– drug-conjugated; tyrosine kinase inhibitors; target therapy; monoclonal antibodies; immunotherapy; natural compounds
(This special issue belongs to the Section Molecular Medicine)
Mitochondrial Quality Control in Aging and Neurodegeneration
edited by Sofie Lautrup
submission deadline 30 Sep 2024 | 5 articles | Viewed by 13374 | Submission Open
Keywords: mitochondria; quality control; mitochondrial biogenesis; mitochondrial dynamics; fission; fusion; mitophagy; mitochondrial degradation; cellular metabolism; aging; neurodegeneration; neurodegenerative diseases; Alzheimer’ s disease; Parkinson’ s disease
(This special issue belongs to the Section Cellular Biochemistry)
Functional Peptides and Their Interactions submission deadline 30 Sep 2024 | 5 articles | Viewed by 9150 | Submission Open
Keywords: naturally occurring peptides; peptide engineering; peptide interactions; peptide self-assembly; peptide structure; small proteins; molecular therapeutics; biomaterials; biocatalysts
(This special issue belongs to the Section Molecular Structure and Dynamics)
Advances in β3-Adrenoceptor submission deadline 30 Sep 2024 | 4 articles | Viewed by 8450 | Submission Open
Keywords: β 3-adrenoceptor; cardiovascular diseases; cancer; prematurity; hypoxia/hyperoxia; neurodegenerative diseases; retinopathy
Novel Insights into Autoimmune/Autoinflammatory Skin Diseases submission deadline 30 Sep 2024 | 5 articles | Viewed by 7020 | Submission Open
Keywords: autoimmune/autoinflammatory skin diseases; omics; bioinformatics; pathogenesis; tailored medicine
(This special issue belongs to the Section Molecular Medicine)
Interface of Aging and Biomaterials: 2nd Edition
edited by
submission deadline 30 Sep 2024 | 3 articles | Viewed by 6471 | Submission Open
Keywords: aging; senescence; geroscience; biomolecules; biomaterials; biocompatibility; nanoparticles; hydrogels
(This special issue belongs to the Section Biological and Bio- Materials)
Biomarkers of Cardiovascular and Cerebrovascular Diseases submission deadline 30 Sep 2024 | 5 articles | Viewed by 4743 | Submission Open
Keywords: biomarkers; cardiovascular disease; cerebrovascular disease; cardiovascular therapy; diagnosis
(This special issue belongs to the Section Molecular Biomarkers)
Programmed Cell Death (Apoptosis): Molecular Mechanisms and Implications for New Drug Discovery submission deadline 30 Sep 2024 | 1 articles | Viewed by 2531 | Submission Open
Keywords: programmed cell death; apoptosis; molecular aspects of apoptosis; apoptosis regulation; drug discovery; emerging therapeutic approaches
(This special issue belongs to the Section Cellular Biochemistry)
The Role of Cholinesterases in Alzheimer’s Disease and Other Neurodegenerative Disorders
edited by
submission deadline 30 Sep 2024 | 2 articles | Viewed by 2280 | Submission Open
Keywords: Alzheimer’ s disease; acetylcholinesterase; butyrylcholinesterase; enzymatic properties; non-enzymatic properties; neuroinflammation; drug development; neuroimaging
(This special issue belongs to the Section Natural and Bio-derived Molecules)
Aptamer Therapeutics in Cancers: New Advances and Future Trends submission deadline 30 Sep 2024 | 1 articles | Viewed by 1982 | Submission Open
Keywords: aptamers; cancer; targeted therapy; aptamer-based conjugates; aptamer-conjugated nanoparticles
(This special issue belongs to the Section Molecular Medicine)
Targeting Neuroinflammation and Insulin Resistance for a Healthy Brain: Prevention and Treatment of Neurological and Psychiatric Disorders submission deadline 30 Sep 2024 | 1 articles | Viewed by 1601 | Submission Open
Keywords: insulin receptor substrates; microglia; degenerative diseases; psychiatric disorders; nutrition
(This special issue belongs to the Section Molecular Medicine)
Recent Trends in Kidney and Cardiovascular Diseases
edited by
submission deadline 30 Sep 2024 | 1 articles | Viewed by 1531 | Submission Open
Keywords: chronic kidney disease; cardiovascular risk; albuminuria; epidemiology; estimated glomerular filtration rate
(This special issue belongs to the Section Molecular Medicine)
The Role of Modulating Intracellular Signaling in Immune System
edited by
submission deadline 30 Sep 2024 | 1 articles | Viewed by 1085 | Submission Open
Keywords: signaling pathway; inflammation; autoimmune disease; treatment
(This special issue belongs to the Section Molecular Biology)
New Insights into the Membranes of Anoxygenic Phototrophic Bacteria submission deadline 30 Sep 2024 | 1 articles | Viewed by 946 | Submission Open
Keywords: anoxygenic phototrophs; light harvesting; membrane dynamics; molecular evolution; reaction centers
(This special issue belongs to the Section Molecular Structure and Dynamics)
Glial Cross-Talk in Central Nervous System Health and Disease submission deadline 30 Sep 2024 | 1 articles | Viewed by 899 | Submission Open
Keywords: glial physiology; glial cross-talk in CNS homeostasis; glial cross-talk in neuroinflammation; glial cross-talk in CNS diseases
(This special issue belongs to the Section Molecular Biology)
Genetic and Structural Analyses of SARS-CoV-2 and Its Variants
edited by
submission deadline 30 Sep 2024 | 1 articles | Viewed by 718 | Submission Open
Keywords: SARS-CoV-2 variants; protein variants; protein structure; virus evolution; mutations; structural bioinformatics; molecular phylogenesis; host– pathogen molecular interactions; molecular immunology; drug discovery
(This special issue belongs to the Section Molecular Structure and Dynamics)
Cutting-Edge Research on the Analysis of Small Biomolecules in Foods, Plants, and Biological Samples, Volume II submission deadline 30 Sep 2024 | 1 articles | Viewed by 708 | Submission Open
Keywords: bioactive food ingredients (primary and secondary metabolites); secondary metabolites— natural products liquid chromatography-mass spectrometry; Fourier transform infrared (FTIR) and Raman spectroscopic analysis; gas chromatography-mass spectrometry; high-resolution mass spectrometry; lipids— amino acids— carbohydrates; polyphenols– terpenes
(This special issue belongs to the Section Natural and Bio-derived Molecules)
Rare Diseases: From Molecular Pathways to Therapeutic Strategies 2.0
edited by
submission deadline 30 Sep 2024 | Viewed by 622 | Submission Open
Keywords: adeno-associated virus  ; gene editing  ; metabolic diseases  ; lysosomal disorders  ; CRISPR  ; inborn errors of metabolism  ; neuromuscular disease
(This special issue belongs to the Section Molecular Medicine)
Insights into the Oral Microbiome and Its Modulation submission deadline 30 Sep 2024 | Viewed by 529 | Submission Open
Keywords: oral microbiome; oral infectious diseases; systemic disease
(This special issue belongs to the Section Molecular Biology)
Epigenetics in Parathyroid Tumors submission deadline 30 Sep 2024 | Viewed by 340 | Submission Open
Keywords: parathyroid disorders; parathyroid adenomas; parathyroid cancers; epigenetics; LncRNAs; microRNAs; circular RNAs; DNA methylation; DNA acetylation
(This special issue belongs to the Section Molecular Medicine)
Gene Mutations in Retinal Dystrophies
edited by Benedetto Falsini and
submission deadline 30 Sep 2024 | Viewed by 278 | Submission Open
Keywords: genes; retina; inherited retinal dystrophies; phenotype
Plant-Microbe-Insect Interactions
edited by and Xueke Gao
submission deadline 30 Sep 2024 | Viewed by 263 | Submission Open
Keywords: plant– microbe– insect interactions; plant defense; insects; pest control; microbiology
(This special issue belongs to the Section Cellular Biochemistry)
Advanced Organometallic Syntheses for Biomedical Applications
edited by Bala Krishna Moku
submission deadline 30 Sep 2024 | Viewed by 228 | Submission Open
Keywords: advanced organometallic syntheses; biomedical applications; drug discovery; disease treatment; imaging; targeted therapy
(This special issue belongs to the Section Synthetic Biology and Bioengineering)
Recent Advances in the Structural and Functional Properties of Glutamate Dehydrogenase
edited by
submission deadline 30 Sep 2024 | Viewed by 207 | Submission Open
Keywords: glutamate dehydrogenase; GLUD1; GLUD2; structure-function relationships; neurodegenerative disorders
(This special issue belongs to the Section Enzymology)
Biomolecules in Forensic Molecular Genetics
edited by
submission deadline 30 Sep 2024 | Viewed by 204 | Submission Open
Keywords: forensic; DNA; RNA; protein; mtDNA; epigenetics; microbiome
(This special issue belongs to the Section Molecular Genetics)
New Insights and Potential Therapeutic Options in Leukemia Metabolism Research
edited by
submission deadline 30 Sep 2024 | Viewed by 193 | Submission Open
Keywords: acute myeloid leukemia (AML); chronic myeloid leukemia (CML); acute lymphocytic leukemia (ALL); chronic lymphocytic leukemia (CLL); tumor metabolism; metabolic rewiring
(This special issue belongs to the Section Molecular Medicine)
New Insights into Kidney Disease Development and Therapy Strategies submission deadline 1 Oct 2024 | 3 articles | Viewed by 3539 | Submission Open
(This special issue belongs to the Section Molecular Medicine)
Molecular Advances in Rett Syndrome and Other Chromatin Related Disorders
edited by and Salvatore Fioriniello
submission deadline 1 Oct 2024 | Viewed by 245 | Submission Open
Keywords: Rett syndrome and other chromatin disorders; epigenetic diseases; molecular alterations in Rett syndrome and other chromatin diseases; novel genes associated with chromatin disorders; MeCP2-mediated molecular mechanisms; roles of epigenetic modulators in chromatin-related diseases; preclinical studies for chromatin diseases; novel diagnostic; prognostic and therapeutic approaches for chromatin disorders
(This special issue belongs to the Section Molecular Medicine)
Molecular Pathology, Diagnostics and Therapeutics of Retinal Diseases
edited by
submission deadline 15 Oct 2024 | 6 articles | Viewed by 17894 | Submission Open
Keywords: retina; macula; macular edema; inflammatory mediators; optical coherence tomography; retinal imaging; biochemical marker; biomarker; pharmacological targeting
(This special issue belongs to the Section Molecular Medicine)
Muscular Dystrophy: From Molecular Basis to Therapies submission deadline 15 Oct 2024 | 5 articles | Viewed by 16962 | Submission Open
Keywords: muscular dystrophies; muscle regeneration; extracellular matrix; satellite cells; therapeutic approaches; animal models; clinical trials
(This special issue belongs to the Section Molecular Biology)
Mechanisms and Kinetics of Interactions of Biomolecules at Interfaces: 2nd Edition submission deadline 15 Oct 2024 | 4 articles | Viewed by 8027 | Submission Open
Keywords: biomolecule adsorption; kinetics of biomolecule adsorption; mechanisms of biomolecule deposition; interactions of biomolecules; techniques for the detection of biomolecules at solid substrates; interactions of proteins with biomolecules/biopolymers; protein and biomolecule systems; protein and biomolecule complexes
(This special issue belongs to the Section Biological and Bio- Materials)
Antibiotic Resistance Mechanisms and Their Potential Solutions
edited by Sung-Pin Tseng, and
submission deadline 15 Oct 2024 | 3 articles | Viewed by 5658 | Submission Open
Keywords: antibiotic resistance; antimicrobial development; molecular mechanism; priority for antibiotics; newly therapeutic approach
(This special issue belongs to the Section Molecular Biology)
TRP Channels in Cardiovascular and Inflammatory Disease
edited by and Soraia Katia Pereira Costa
submission deadline 15 Oct 2024 | 3 articles | Viewed by 4900 | Submission Open
(This special issue belongs to the Section Molecular Medicine)
New Insights into Cardiovascular Immunology
edited by Susanne Sattler, Pilar Martín and Stephen Malin
submission deadline 15 Oct 2024 | 1 articles | Viewed by 2597 | Submission Open
Keywords: inflammation; autoimmunity; atherosclerosis; myocarditis; heart failure
(This special issue belongs to the Section Molecular Medicine)
Role of Neuroactive Steroids in Health and Disease: 2nd Edition submission deadline 15 Oct 2024 | 3 articles | Viewed by 1778 | Submission Open
Keywords: neurosteroids; neurodegenerative disorders; psychiatric disorders; physiological effects
(This special issue belongs to the Section Molecular Biology)
Molecular and Cell Biology in Endometriosis and Endometrial Cancer: 2nd Edition submission deadline 15 Oct 2024 | 1 articles | Viewed by 923 | Submission Open
Keywords: endometriosis; endometrial cancer; ovarian cancer; molecular basis of endometriosis and endometrial cancer; single cell transcriptomics; spatial transcriptomics; multiomics; genomics; proteomics; epigenomics; metabolomics
(This special issue belongs to the Section Molecular Biology)
Bionanomaterials: Synthesis, Characterization, Toxicity and Biomedical Applications (Volume II) submission deadline 20 Oct 2024 | 5 articles | Viewed by 8529 | Submission Open
Keywords: nanoparticles; nano-alloys; graphene; nanotubes; hybrid nanomaterials; green synthesis; cytotoxicity; systemic toxicity; modulation of the biological impact; nanomaterials as diagnostic and therapeutic platforms; potential applications in medicine
(This special issue belongs to the Section Biological and Bio- Materials)
Molecular Basis of Cardiac Fibrotic Remodeling: Prognosis of Fibrosis in the Heart
edited by and
submission deadline 20 Oct 2024 | 3 articles | Viewed by 7026 | Submission Open
Keywords: cardiac fibrosis; atrial fibrotic remodeling; cardiac repair; extracellular matrix remodeling; differentiation of fibroblasts to myofibroblasts; activation of cardiac fibroblasts
(This special issue belongs to the Section Molecular Biology)
Gametogenesis and Gamete Interaction, 2nd Edition
edited by
submission deadline 26 Oct 2024 | Viewed by 112 | Submission Open
Keywords: gametogenesis and meiosis; sperm attraction and activation; gamete interaction and recognition; species specificity and self/nonself-recognition in hermaphrodites; acrosome reaction sperm penetration of egg coat; gamete membrane fusion; polyspermy block; egg activation
(This special issue belongs to the Section Molecular Reproduction)
NAD Metabolism in Physiology and Pathology
edited by Mathias Ziegler
submission deadline 30 Oct 2024 | 1 articles | Viewed by 1476 | Submission Open
Keywords: NAD; ADP-ribosylation; sirtuins; redox homeostasis; NAD glycohydrolases
(This special issue belongs to the Section Molecular Medicine)
Development, Characterization, and Application of Bioactive Peptides, Diagnostic Biomarkers, and Pharmaceutical Proteins
edited by and Ji-Hun Kim
submission deadline 31 Oct 2024 | 10 articles | Viewed by 17409 | Submission Open
Keywords: bioactive peptides; biomarker proteins; pharmaceutical proteins; protein engineering; protein/peptide nanoparticles; protein/peptide production process; enzymology; antibody technology
(This special issue belongs to the Section Biomacromolecules: Proteins)
Insights of Innate Immunology into Inflammation and Infections
edited by , Bo Liu and
submission deadline 31 Oct 2024 | 6 articles | Viewed by 12827 | Submission Open
Keywords: innate immunity; innate immune cells; inflammation; infection
(This special issue belongs to the Section Molecular Medicine)
DNA Damage and DNA Repair in Cancer submission deadline 31 Oct 2024 | 6 articles | Viewed by 11054 | Submission Open
Keywords: DNA damage; DNA repair; cancer; therapy; radiation biology; systems biology
(This special issue belongs to the Section Biomacromolecules: Nucleic Acids)
Biomarkers in Oral Diseases 2.0 submission deadline 31 Oct 2024 | 4 articles | Viewed by 8319 | Submission Open
Keywords: oral cancer; oral carcinogenesis; oral potentially malignant disorders; oral manifestations of autoimmune mediated diseases; periodontal diseases; head and neck pathology
(This special issue belongs to the Section Molecular Biomarkers)
Skeletal Muscle Homeostasis and Regeneration
edited by
submission deadline 31 Oct 2024 | 5 articles | Viewed by 8281 | Submission Open
Keywords: skeletal muscle; homeostasis; regeneration; satellite cells; fiber type
(This special issue belongs to the Section Molecular Medicine)
In Silico Drug Design and Discovery: Big Data for Small Molecule Design 2nd Edition submission deadline 31 Oct 2024 | 4 articles | Viewed by 8213 | Submission Open
Keywords: drug discovery; medicinal chemistry; chemoinformatics; bioinformatics; machine learning; deep learning
(This special issue belongs to the Section Bioinformatics and Systems Biology)
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