Foot and Ankle Surgery: Current Progresses and Emerging Technologies in Orthoplastic Reconstruction

A special issue of Bioengineering (ISSN 2306-5354). This special issue belongs to the section "Regenerative Engineering".

Deadline for manuscript submissions: closed (15 February 2024) | Viewed by 556

Special Issue Editor


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Guest Editor
International Center for Limb Lengthening, Rubin Institute for Advanced Orthopedics, Sinai Hospital of Baltimore, Baltimore, MD, USA
Interests: microsurgical revascularization of bone; autologous & allogeneic heterotopic bone banking; enhanced healing of skin graft donor sites in multimorbid patients with processed human dermal allograft; enhanced tissue healing with cleaved collagen substrates

Special Issue Information

Dear Colleagues,

The fields of tissue engineering and the techniques used to augment and improve the healing of multiple organ systems continue to have a tremendous positive impact on patient health. Improved clinical outcomes are often the direct result of advances in tissue engineering, which are possible due to a combination of the scientists’ research work and the creativity and skill of the surgeon. Indeed, the limitations of these remarkable biomaterial substates are most often perceived and evaluated by the benchtop scientists, but the applications of them are often also only limited on by the creativity and skill of clinicians. In this Special Issue of Bioengineering, entitled “Foot and Ankle Surgery: Current Progresses and Emerging Technologies in Orthoplastic Reconstruction”, we aim to highlight several impactful tissue-healing products and surgical techniques from both the scientific/industrial and clinical viewpoints. With this Special Issue, we hope to compile a collection of research studies through which any reader will be able to come away with an immediate clinical application or technique to improve clinical outcomes, especially in difficult cases.

Dr. Christopher Bibbo
Guest Editor

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Keywords

  • bioengineered tissues
  • orthoplastics
  • bone healing
  • surgical outcomes
  • high-risk patients

Published Papers (1 paper)

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Review

24 pages, 8584 KiB  
Review
Decellularized Human Dermis for Orthoplastic Extremity Reconstruction
by Christopher Bibbo and K. Ümit Yüksel
Bioengineering 2024, 11(5), 422; https://doi.org/10.3390/bioengineering11050422 - 25 Apr 2024
Viewed by 376
Abstract
The reconstruction of patients who possess multi morbid medical histories remains a challenge. With the ever-increasing number of patients with diabetes, infections, and trauma, there is a consistent need for promotion of soft tissue healing and a reliable substrate to assist with every [...] Read more.
The reconstruction of patients who possess multi morbid medical histories remains a challenge. With the ever-increasing number of patients with diabetes, infections, and trauma, there is a consistent need for promotion of soft tissue healing and a reliable substrate to assist with every aspect of soft tissue reconstruction, as well as the loss of fascial domain. Several proprietary products filled some of these needs but have failed to fulfill the needs of the clinician when faced with reconstructing multiple soft tissue systems, such as the integument and the musculoskeletal system. In this paper we discuss the use of decellularized human dermis (DermaPure®, Tissue Regenix, Universal City, TX, USA) through which a unique human tissue processing technique (dCELL® technology, Tissue Regenix, Universal City, TX, USA) and the creation of multiple product forms have proven to exhibit versatility in a wide range of clinical needs for successful soft tissue reconstruction. The background of human tissue processing, basic science, and early clinical studies are detailed, which has translated to the rationale for the success of this unique soft tissue substrate in orthoplastic reconstruction, which is also provided here in detail. Full article
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