Special Issues

Antibiotics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Antimicrobial Resistance Genes: Spread and Evolution submission deadline 29 Jun 2025 | 7 articles | Viewed by 13192 | Submission Open
Keywords: microbes; antimicrobial resistance; resistance genes; gene flow; evolution
(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)
Natural Products and Bio-Nanomaterials: Novel Strategies to Overcome Antibiotic Resistance
edited by , Gerson Nakazato and
submission deadline 30 Jun 2025 | 9 articles | Viewed by 32129 | Submission Open
Keywords: nanotechnology; material; antimicrobial; nature; resistance; nanoparticles; strategy
(This special issue belongs to the Section Plant-Derived Antibiotics)
Antimicrobial Resistance and Therapy in Intensive Care Unit
edited by , Borja Suberviola and
submission deadline 30 Jun 2025 | 9 articles | Viewed by 28271 | Submission Open
Keywords: ICU; sepsis; antimicrobial; multidrug-resistant bacteria; sepsis; antimicrobial stewardship
(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)
Computational Approaches in Discovery and Design of Antimicrobial Peptides—2nd Edition submission deadline 30 Jun 2025 | 7 articles | Viewed by 20590 | Submission Open
Keywords: rational search and design of AMPs; alignment-based and alignment-free approaches; machine-learning; artificial intelligence; biodiscovery with associated computational analyses/tools; non-conventional in silico approaches
(This special issue belongs to the Section Antimicrobial Peptides)
Optimizing Antimicrobial Use: Antimicrobial Stewardship and Surveillance
edited by Jesus Ruiz-Ramos
submission deadline 30 Jun 2025 | 6 articles | Viewed by 16677 | Submission Open
Keywords: antimicrobial stewardship; antimicrobial cycling; antimicrobial resistance; decision support; antibiotic optimization; antibiotic therapy
(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)
Combination Therapy against Multidrug-Resistant Pathogens
edited by and
submission deadline 30 Jun 2025 | 6 articles | Viewed by 15327 | Submission Open
Keywords: combination therapy; multidrug-resistant pathogens; in vitro; in vivo; clinical study; pharmacokinetics; pharmacodynamics.
(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)
Clinical Pharmacokinetics, Pharmacodynamics, and/or TDM of Antimicrobial Agents
edited by
submission deadline 30 Jun 2025 | 5 articles | Viewed by 6373 | Submission Open
Keywords: pharmacokinetics/pharmacodynamics; therapeutic drug monitoring; antimicrobial resistant; AI; antimicrobial stewardship
(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics of Drugs)
Development of Antimicrobial Peptides from Amphibian, 2nd Edition
edited by , and Maria Rosa Loffredo
submission deadline 30 Jun 2025 | 3 articles | Viewed by 5631 | Submission Open
Keywords: frog skin-derived antimicrobial peptides; natural and synthetic AMPs; the synergy of AMPs; insights into the mechanism(s) of action of AMPs; drug delivery system
(This special issue belongs to the Section Antimicrobial Peptides)
Antimicrobial Stewardship and Optimizing Antibiotic Dose in Critically Ill Patients
edited by Barbara J. Philips
submission deadline 30 Jun 2025 | 3 articles | Viewed by 5314 | Submission Open
Keywords: antibiotics; antimicrobials; intensive care; critical care; sepsis; pharmacokinetics; pharmacodynamics; stewardship; beta-lactams; aminoglycosides; quinolones; cephalosporins; antifungal
(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics of Drugs)
Advances in the Discovery of Novel Antimicrobial Agents in Nature and Their Applications, 2nd edition submission deadline 30 Jun 2025 | 3 articles | Viewed by 5172 | Submission Open
Keywords: antimicrobial agents; antimicrobial mechanisms; natural products
(This special issue belongs to the Section Biosynthesis and Combinatorial Approaches in Antimicrobial Discovery)
Antibiotics Stewardship in Low and Middle-Income Countries submission deadline 30 Jun 2025 | 2 articles | Viewed by 3663 | Submission Open
Keywords: antimicrobial resistance (AMR); low and middle-income countries (LMICs); multidrug-resistant (MDR) strains; One Health; public health; animal health; environmental impact; healthcare; sanitation and hygiene; preventive medine; epidemiological surveillance
(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)
Irrational Antibiotic Use in Primary Care
edited by , Luwen Shi and Paul Little
submission deadline 30 Jun 2025 | 2 articles | Viewed by 3364 | Submission Open
Keywords: irrational antibiotic use; antimicrobial resistance; drivers; primary care
(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)
New Insights into Prevention, Diagnosis, and Treatment of Neonatal Sepsis and Short- and Long-Term Outcomes
edited by , and Maria Baltogianni
submission deadline 30 Jun 2025 | 2 articles | Viewed by 3200 | Submission Open
Keywords: neonate; sepsis; early sepsis; late sepsis; antibiotic resistance; multiple resistance antibiotics; antibiotics stewardship
(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)
Prevention and Antimicrobial Surveillance of Hospital-Associated Infections
edited by Theodouli Stergiopoulou
submission deadline 30 Jun 2025 | 2 articles | Viewed by 2855 | Submission Open
Keywords: infection monitoring; surveillance program; antimicrobial surveillance; healthcare-associated infections
(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)
Antibiotics Use for Respiratory Diseases submission deadline 30 Jun 2025 | 1 articles | Viewed by 2602 | Submission Open
Keywords: antimicrobial resistance; respiratory diseases; diagnostics; co-infection; healthcare-associated infection
(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)
A One Health Approach to Antimicrobial Resistance, 2nd Edition
edited by
submission deadline 30 Jun 2025 | 3 articles | Viewed by 2474 | Submission Open
Keywords: One Health; antibiotic; antimicrobial resistance; animal; food; environment
Multidrug-Resistant Gram-Negative Bacteria Infections: Current Epidemiology, Prognosis and Treatment Options
edited by Novella Carannante
submission deadline 30 Jun 2025 | 1 articles | Viewed by 2420 | Submission Open
Keywords: multidrug-resistant gram-negative bacteria; epidemiology and prognosis; antibiotic treatment options; antimicrobial resistance; infection control and antibiotic use
(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)
Antimicrobial Activities of Bioactive Components from Honeybee Products submission deadline 30 Jun 2025 | 1 articles | Viewed by 2132 | Submission Open
Keywords: bee products; antibiotics; antimicrobial activity; bioactive compounds; honey; propolis; bee pollen/beebread; royal jelly; bee venom; microbial resistance
(This special issue belongs to the Section Novel Antimicrobial Agents)
Antibiotic Resistance and Virulence in Bacterial Isolates: A Genomic Perspective from Human and Animal Sources submission deadline 30 Jun 2025 | 1 articles | Viewed by 615 | Submission Open
Keywords: MDRB; antimicrobial resistance; one health; mobile genetic elements; AMR; antimicrobial resistance gene
(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)
Antibiotic Therapy in Respiratory Tract Infections (RTIs)
edited by Ágnes Tóth and
submission deadline 30 Jun 2025 | Viewed by 598 | Submission Open
Keywords: antibiotic therapy; respiratory tract infections; clinical guidelines; prescribing practices; antibacterial resistance; antimicrobial stewardship
(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)
Clinical Pharmacology and Pharmacy of Antimicrobial Agents, 2nd Edition submission deadline 30 Jun 2025 | Viewed by 350 | Submission Open
Keywords: antibiotics; antifungals; antiviral agents; antiparasitic agents; pharmacology; pharmacy; pharmacoepidemiology; drug utilization research; pharmacodynamics; pharmacokinetics; toxicology; interactions; drug combinations; repositioning; synergism
(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics of Drugs)
Dermatological Infections and Antibiotic Treatment
edited by
submission deadline 30 Jun 2025 | Viewed by 346 | Submission Open
Keywords: dermatological infections; antibiotic resistance; antibiotics; antibiotic treatment
(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)
Antimicrobial and Antioxidant Efficacy of Essential Oils
edited by
submission deadline 30 Jun 2025 | Viewed by 336 | Submission Open
Keywords: essential oils; chemical analysis; extraction methods; antimicrobial activity; antioxidant potential
(This special issue belongs to the Section Plant-Derived Antibiotics)
Recent Advances in Efflux Pump Inhibitors and Their Role in Combatting Multidrug Resistance submission deadline 30 Jun 2025 | Viewed by 328 | Submission Open
Keywords: multidrug resistance; multidrug efflux pump; efflux pump inhibitor (EPI); accumulation assay; efflux assay; fluorochromes; ethidium bromide; quorum sensing; biofilm
(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)
Drivers of Virulence and Antimicrobial Resistance in Emerging and Re-Emerging Pathogens
edited by , and Ingrid Maria Cecilia Rubin
submission deadline 30 Jun 2025 | Viewed by 218 | Submission Open
Keywords: AMR; microbial pathogenesis; microbial ecology; pathogen dynamics; genomic epidemiology; multiomics; microbial interactions; AI/ML
(This special issue belongs to the Section Genetic and Biochemical Studies of Antibiotic Activity and Resistance)
Antimicrobial Extracts and Compounds Derived from Plants
edited by
submission deadline 30 Jun 2025 | Viewed by 188 | Submission Open
Keywords: antibacterial; antifungal; plant extract; plant compounds; antibiotic-resistant strains; virulence factors; synergistic interactions
(This special issue belongs to the Section Plant-Derived Antibiotics)
Periodontal Bacteria and Periodontitis: Infections and Therapy
edited by Anna Skurska
submission deadline 30 Jun 2025 | Viewed by 156 | Submission Open
Keywords: periodontitis; infection; antibiotics; antibacterial activities
(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)
Antimicrobial Therapy in Oral Diseases submission deadline 5 Jul 2025 | 3 articles | Viewed by 9225 | Submission Open
Keywords: oral; antibiotic; antiseptic; tooth; periodontium; dental caries; implant; healing; cell; biomaterials; periodontitis; biocompatibility; toxicity; periodontology; periodontal pocket; bacteria; nonsurgical treatment; oral surgery; clinical trial
(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)
Epidemiology, Clinical Microbiology and Antimicrobial Therapy: A Shared Effort against Infectious Diseases
edited by Francesca Pica
submission deadline 15 Jul 2025 | 10 articles | Viewed by 18666 | Submission Open
Keywords: microbes and antimicrobials; bacteria; fungi and viruses; antibiotics; antifungals and antivirals; antimicrobial resistance; rapid diagnostics; genotypic and phenotypic resistance; epidemiology; public health; infectious diseases; hospital-acquired infections (HAIs); community infections; natural and synthetic antimicrobial compounds
(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)
Epidemiology, Diagnosis and Antimicrobial Treatment of Hospital-Acquired Infections submission deadline 15 Jul 2025 | 4 articles | Viewed by 5521 | Submission Open
Keywords: hospital-acquired infection; bacteremia; bloodstream infection; pneumonia; ventilator-associated pneumonia; urinary tract infection
(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)
Impact of Plant-Derived Products as Novel Antimicrobial Agents
edited by Eleonora Spinozzi
submission deadline 15 Jul 2025 | Viewed by 154 | Submission Open
Keywords: natural compounds; plant bacteria; fungal infections; antimicrobial
(This special issue belongs to the Section Plant-Derived Antibiotics)
Antimicrobial Activity of Bioactive Peptides and Their Derivatives
edited by Alexandro Rodríguez-Rojas
submission deadline 20 Jul 2025 | 7 articles | Viewed by 10337 | Submission Open
Keywords: antimicrobial resistance (AMR); global health threat; novel antimicrobial agents; bioactive peptides (AMPs); natural antimicrobial agents; broad-spectrum activity; antimicrobial activity; mechanisms of action; structure– activity relationships; AMP-based therapeutics; clinical applications of AMPs; combinatory therapy
(This special issue belongs to the Section Antimicrobial Peptides)
Plant Extracts and Natural Products for the Control of Animal Pathogens in a ONE-Health Perspective
edited by Ernesto Palma, and Carmine Lupia
submission deadline 20 Jul 2025 | 1 articles | Viewed by 1213 | Submission Open
Keywords: natural products; essential oils; hive products; colostrum; pets; livestock; drug resistances; antimicrobial resistances; sustainable pathogen control; animal health and welfare
(This special issue belongs to the Section Antibiotics in Animal Health)
Foodborne Pathogens: The Rise of Virulence and Antimicrobial Resistance submission deadline 20 Jul 2025 | Viewed by 226 | Submission Open
Keywords: foodborne pathogens; antimicrobial resistance; virulence factors; food chain; antibiotic overuse; public health; food safety; zoonotic diseases; one health
Novel Approaches for the Treatment of Antimicrobial-Resistant Pathogens
edited by
submission deadline 31 Jul 2025 | 2 articles | Viewed by 40769 | Submission Open
Keywords: antimicrobial resistance diagnosis and surveillance; antibiotic alternatives and development of novel drugs; whole-genome sequencing; gut microbiota; infectious pathogens in animals and humans
(This special issue belongs to the Section Novel Antimicrobial Agents)
Antibiotics and Environment − Research and Development toward the One Health Approach
edited by
submission deadline 31 Jul 2025 | 7 articles | Viewed by 26862 | Submission Open
Keywords: antimicrobial resistance (AMR); antimicrobials; water purification plant (WTP); wastewater treatment plant (WWTP); hospital wastewater; livestock environment; aquaculture farm environment; aquatic environment
Antibiotics as Major Disruptors of Gut Microbiota
edited by
submission deadline 31 Jul 2025 | 6 articles | Viewed by 21172 | Submission Open
Keywords: microbiome; gut flora; development of gut flora; dysbiosis; antibiotics; antibiotic classes; antibiotic consumption; gut– brain axis; short-chain fatty acids; metabolom; mediator molecules; composition of gut flora
Alternative Approaches to Treating Antimicrobial Resistant Infections, 3rd Edition submission deadline 31 Jul 2025 | 5 articles | Viewed by 14381 | Submission Open
Keywords: repurposing; anti-infectives; host-targeted therapies; bacteriophages; predatory bacteria; bacteriocins; antimicrobial peptides; nanoparticles; natural compounds; immunotherapy; probiotics; antibiotics
Green Antimicrobials in Biomedical Engineering: Recent Advances Proposal
edited by
submission deadline 31 Jul 2025 | 6 articles | Viewed by 14276 | Submission Open
Keywords: antimicrobial agents concomitant; synergistic and additive effects surface functionalization; antimicrobial properties; biomedical therapies; bioactive molecules; green synthesis; environmentally friendly; circular economy; waste materials’ second life
(This special issue belongs to the Section Novel Antimicrobial Agents)
Genomic Analysis of Antimicrobial Drug-Resistant Bacteria submission deadline 31 Jul 2025 | 6 articles | Viewed by 13465 | Submission Open
Keywords: antimicrobial drug resistance; whole-genome sequencing; genomic epidemiology; one health; bacterial pathogens; mobile genetic elements; horizontal gene transfer; phylogenetics; evolution
(This special issue belongs to the Section Genetic and Biochemical Studies of Antibiotic Activity and Resistance)
Antibiotic Treatment on Surgical Infections
edited by
submission deadline 31 Jul 2025 | 3 articles | Viewed by 12740 | Submission Open
Keywords: surgical site; infection; emergency surgery; prevention
Antimicrobial Resistance in the Community Setting: The Other Side of the Coin
edited by
submission deadline 31 Jul 2025 | 4 articles | Viewed by 12004 | Submission Open
Keywords: emerging resistance; multidrug resistance; emerging virulence; community setting; Staphylococcus aureus; Enterococcus spp.; Streptococcus spp.; Haemophilus spp.; Moraxella spp.; Mycobacterium spp.; Neisseria spp.; Salmonella spp.; Shigella spp.; Campylobacter spp.; anaerobes; fungi
Staphylococcal Biology and Pathogenesis
edited by Richard Proctor
submission deadline 31 Jul 2025 | 5 articles | Viewed by 11426 | Submission Open
Sepsis Management and Antibiotic Therapy submission deadline 31 Jul 2025 | 6 articles | Viewed by 11382 | Submission Open
Keywords: sepsis; antibiotic therapy; infection; antimicrobial; antifungal
(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)
Strategies for Combatting Multidrug-Resistant and Extensively Drug-Resistant Bacteria, 2nd Edition
edited by , Anna Kędziora and
submission deadline 31 Jul 2025 | 6 articles | Viewed by 11058 | Submission Open
Keywords: MDR bacteria; EDR bacteria; novel antimicrobial drugs; novel therapeutical approaches against MDR; novel therapeutical approaches against EDR; guidelines; personalized microbiota; bacteriophages; autovaccine therapy; antimicrobial stewardship
(This special issue belongs to the Section The Global Need for Effective Antibiotics)
Challenges and Emerging Strategies to Tackle the Global Burden of Antimicrobial Resistance submission deadline 31 Jul 2025 | 3 articles | Viewed by 9426 | Submission Open
Keywords: antimicrobial resistance (AMR); global burden of AMR; AMR in the context of public and global health; diagnostic and treatment of AMR; new approaches to AMR surveillance; antibiotic stewardship; local and global policy initiatives on AMR; prevention of AMR
(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)
Clinical Guidelines and Real Practice of Antimicrobial Pharmacotherapy
edited by
submission deadline 31 Jul 2025 | 5 articles | Viewed by 9377 | Submission Open
Keywords: adverse drug reaction; patient adherence; antimicrobial resistance; clinical guidelines; clinical settings; regional factors; pharmacotherapy
(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)
Antimicrobial and Antibiofilm Activity by Natural Compounds
edited by , and Martha Viviana Torres Cely
submission deadline 31 Jul 2025 | 5 articles | Viewed by 8070 | Submission Open
Keywords: pathogens; human; animal; crops; antibiotic
(This special issue belongs to the Section Plant-Derived Antibiotics)
Antibiotics Use and Stewardship in Hospitals and Outpatient Care Facilities, 2nd Edition
edited by and Ahmed El Yazbi
submission deadline 31 Jul 2025 | 5 articles | Viewed by 7641 | Submission Open
Keywords: antimicrobial stewardship; novel antibiotics; microbial resistance; optimizing treatment; pharmacokintics/pharmacodynamics
(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)
Orthopedic Infections: Epidemiology and Antimicrobial Treatment
edited by Éric Bonnet
submission deadline 31 Jul 2025 | 4 articles | Viewed by 6955 | Submission Open
Keywords: chronic osteomyelitis; prosthetic joint infections; epidemiology; microbiology; antimicrobial treatment; treatment duration; local antibiotics
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