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Antibiotics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Rational Use of Antibiotics in Veterinary Medicine

edited by

JeongWoo Kang

submission deadline 15 Jan 2026 | 2 articles | Viewed by 10092 | Submission Open

Keywords: good manufacturing practice (GMP) in antibiotic production; research and systems in antibiotic quality control; consequences of improper antibiotic use; antibiotic stewardship programs; antibiotic resistance management

(This special issue belongs to the Section Antibiotics in Animal Health)

Antibiotic Resistance: The Role of Aquatic Environments

edited by

Jason W. Marion

and Matthew D. Stocker

submission deadline 15 Jan 2026 | 2 articles | Viewed by 4452 | Submission Open

Keywords: antibiotic resistance; water; wastewater; One Health; antibiotic misuse; antimicrobial resistance genes; microbiology; fecal indicator bacteria; mobile genetic elements; resistome; pollution; environment; water bodies; water treatment; waterborne disease; public health; risk assessment; sanitation; hygiene; aquatic environments

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

The Discovery of Novel Beta-Lactams and Beta-Lactamase Inhibitors

edited by

Caitlyn Thomas

and

Juhee Ahn

submission deadline 15 Jan 2026 | Viewed by 434 | Submission Open

Keywords: antibiotic resistance; β -lactam antibiotics; β -lactamase inhibitors; drug discovery; metallo-β -lactamases; serine-β -lactamase

Strategies for Combating Antibiotic Resistance: From Mechanisms to Drug Discovery

edited by Angel Leon-Buitimea

submission deadline 15 Jan 2026 | Viewed by 289 | Submission Open

Keywords: antibiotic resistance; clinically relevant bacteria; multidrug-resistant bacteria; pan-drug-resistant bacteria; drug discovery; combinatorial treatments

Advances in Antimicrobial Treatment of Periodontitis

edited by

Thomas E. Rams

submission deadline 15 Jan 2026 | Viewed by 264 | Submission Open

Keywords: periodontitis; periodontal chemotherapy; anti-infective periodontal therapy; antibiotic therapy

Molecular and Therapeutic Insights into Antimicrobial Candidates and Antibiotics

edited by

Fabio Aguiar Alves

and

Bruno de Araujo Penna

submission deadline 15 Jan 2026 | Viewed by 244 | Submission Open

Keywords: antimicrobial resistance; novel antimicrobial agents; molecular mechanisms; therapeutic applications

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

New Insights into Prevention, Diagnosis, and Treatment of Neonatal Sepsis and Short- and Long-Term Outcomes

edited by

Vasilios Giapros

Dimitrios Rallis

and Maria Baltogianni

submission deadline 20 Jan 2026 | 2 articles | Viewed by 5503 | Submission Open

Keywords: neonate; sepsis; early sepsis; late sepsis; antibiotic resistance; multiple resistance antibiotics; antibiotics stewardship

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Antibiotic Use and Stewardship in Settings Outside of Acute Hospitals

edited by Monsey McLeod and Naomi Fleming

submission deadline 30 Jan 2026 | 1 articles | Viewed by 675 | Submission Open

Keywords: antimicrobial stewardship; antibiotic use; community; primary care; mental health; local authority; care home; public; health and justice; dental

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Discovery and Synthesis of Antimicrobial Compounds Against Multidrug Resistance

edited by

Anita Cohen

submission deadline 31 Jan 2026 | 4 articles | Viewed by 43660 | Submission Open

Keywords: antimicrobial resistance; medicinal chemistry; (pre)clinical development; intrinsic/synergistic activity; innovative antibiotic treatment; antimicrobial drug-candidate; new and repurposed medicines

(This special issue belongs to the Section Novel Antimicrobial Agents)

Antibiotic Resistance in Wastewater Treatment Plants

edited by Qingbin Yuan

submission deadline 31 Jan 2026 | 5 articles | Viewed by 9960 | Submission Open

Keywords: antibiotic resistance genes; wastewater treatment; one health; distribution and removal of ARGs; horizontal gene transfer

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Advances in the Field of Biofilm-Associated Musculoskeletal Infections

edited by

Kordo Saeed

submission deadline 31 Jan 2026 | 5 articles | Viewed by 9917 | Submission Open

Keywords: musculoskeletal infections; biofilm-associated; mycobacterial-associated; implant-related infections

(This special issue belongs to the Section Antibiofilm Strategies)

Multidrug-Resistant Gram-Negative Bacteria Infections: Current Epidemiology, Prognosis and Treatment Options

edited by Novella Carannante

submission deadline 31 Jan 2026 | 5 articles | Viewed by 9736 | Submission Open

Keywords: multidrug-resistant gram-negative bacteria; epidemiology and prognosis; antibiotic treatment options; antimicrobial resistance; infection control and antibiotic use

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Microbial Biofilms: Identification, Resistance and Novel Drugs

edited by

Célia Fortuna Rodrigues

and

Susana Patrícia Lopes

submission deadline 31 Jan 2026 | 3 articles | Viewed by 8753 | Submission Open

Keywords: biofilm; resistance; pathogens; alternative treatment; plant extract; peptides; nanotechnology

(This special issue belongs to the Section Antibiofilm Strategies)

Challenges and Strategies for the Antibiotic Resistance Crisis

edited by

Manuel Simões

and

Marc Maresca

submission deadline 31 Jan 2026 | 5 articles | Viewed by 7975 | Submission Open

Keywords: antibiotics stewardship; antimicrobial use; antibiotics resistance; novel antimicrobial agents; multidisciplinary antimicrobial strategies; antibiotic clinical studies; artificial intelligence strategies

Single-Stage Management of Musculo-Skeletal Infections: Local Antibacterial Protection, Antibiotics, and Surgical Treatments

edited by

Guillem Bori

and

Carlo L. Romanò

submission deadline 31 Jan 2026 | 3 articles | Viewed by 7357 | Submission Open

Keywords: knee arthroplasty; hip arthroplasty; shoulder arthroplasty; antibiotic treatment; one-stage revision arthroplasty; antibacterial coating

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

The Appropriateness of Antibiotic Prescribing in Hospitals and Ambulatory Care

edited by

Francesco Ferrara

, Roberto Langella and

Andrea Zovi

submission deadline 31 Jan 2026 | 1 articles | Viewed by 6092 | Submission Open

Keywords: pharmacology; antimicrobic resistance; governance; appropriateness; infectivology

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Tracking Reservoirs of Antimicrobial Resistance Genes in Environment

edited by

Mor Nadia Lurie-Weinberger

and

Dror Avisar

submission deadline 31 Jan 2026 | 3 articles | Viewed by 5567 | Submission Open

Keywords: antimicrobial resistance; AMR; environmental reservoirs; antibiotic resistance genes; ARGs; horizontal gene transfer

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Antifungal Strategies: Epidemiological Approaches, Mechanisms and Resistance in Fungal Pathogens

edited by

Erick Martinez-Herrera

Rodolfo Pinto-Almazán

and

Carmen Rodríguez-Cerdeira

submission deadline 31 Jan 2026 | 3 articles | Viewed by 4694 | Submission Open

Keywords: antifungal strategies; epidemiology; antifungal resistance; antifungal mechanisms; resistance genes

(This special issue belongs to the Section Fungi and Their Metabolites)

The Antibiotic Resistance and Virulence Genes of Pathogens in Aquatic and Soil Environment

edited by

Bing Li

submission deadline 31 Jan 2026 | 1 articles | Viewed by 3244 | Submission Open

Keywords: antibiotic resistance genes (ARGs); virulence genes; pathogenic bacteria; horizontal gene transfer

Antimicrobial Stewardship in Surgical Infection

edited by Nuno Rocha-Pereira

submission deadline 31 Jan 2026 | 3 articles | Viewed by 2800 | Submission Open

Keywords: antimicrobial stewardship; surgical infection; surgical site infection; antimicrobial resistance; diagnostic stewardship

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Diagnostics and Antibiotic Therapy in Bone and Joint Infections

edited by Sebastian Meller and Stavros Goumenos

submission deadline 31 Jan 2026 | 4 articles | Viewed by 1968 | Submission Open

Keywords: bone and joint infections; osteomyelitis; implant-related infections; diagnostics; antimicrobials; antibiotic therapy; PJI management; surgical site antisepsis; local antibiotic therapy; diagnostic biomarkers; multidisciplinary infection management; outcome analysis after musculoskeletal infection

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Advances in Antimicrobial Therapies for Oral Infections: From Biofilm Disruption to Clinical Applications

edited by

Cláudia Helena Silva-Lovato

and

Adriana Barbosa Ribeiro

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1492 | Submission Open

Keywords: oral infections; microbial biofilm; antimicrobial therapies

(This special issue belongs to the Section Antibiofilm Strategies)

Antimicrobial Resistance Genes: Spread and Evolution, 2nd Edition

edited by

Angeliki Mavroidi

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1333 | Submission Open

Keywords: microbes; antimicrobial resistance; resistance genes; gene flow; evolution

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Helicobacter pylori Virulence Factors, Antibiotic Susceptibility and Persistent Infection

edited by

Mara Di Giulio

Teresa Fasciana

and

Chiara Pagliuca

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1100 | Submission Open

Keywords: Antimicrobial drugs and therapies; virulence factors; pathogenesis; extra-digestive diseases; gastric microbioma

Superbugs Unleashed: Global Challenges and Solutions for Extensively Drug-Resistant and Pan-Drug-Resistant Pathogens

edited by

Ionela-Larisa Miftode

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1015 | Submission Open

Keywords: antimicrobial resistance; extensively drug-resistant pathogens; pan-drug-resistant bacteria; multidrug-resistant organisms (MDROs); infectious disease control; antibiotic stewardship; novel antimicrobials; rapid diagnostics; global health threats

Evidence-Based Antibiotic Protocols and Digital Innovation in Oral Infection Management: Optimizing Use Through Teledentistry and Modern Diagnostics

edited by

Manlio Santilli

submission deadline 31 Jan 2026 | 1 articles | Viewed by 872 | Submission Open

Keywords: antibiotics; dental infections; oral infections; antibacterial resistance; telemedicine; teledentistry; antimicrobial management; AI-related

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Bacterial Infections and Global Health: The Escalating Threat of Antibiotic Resistance

edited by

Nicola Petrosillo

and

Guido Granata

submission deadline 31 Jan 2026 | Viewed by 613 | Submission Open

Keywords: infection control; antimicrobial stewardship; spread of multidrug-resistant bacteria; methicillin-resistant Staphylococcus aureus; carbapenemases; metallo-β -Lactamase; microbiology diagnostics in field hospitals; One Health

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Neonatal Infection: Antibiotics for Prevention and Treatment

edited by Cinzia Auriti and Maria Paola Ronchetti

submission deadline 31 Jan 2026 | 1 articles | Viewed by 526 | Submission Open

Keywords: neonatal infections; neonatal sepsis; sepsis definition; antibiotics in newborns; antibiotic stewardship; sepsis biomarkers; sepsis diagnosis in newborns; epidemiology of neonatal infections; fungal invasive infections

Dermatological Infections and Antibiotic Treatment

edited by

Oriana Simonetti

submission deadline 31 Jan 2026 | Viewed by 515 | Submission Open

Keywords: dermatological infections; antibiotic resistance; antibiotics; antibiotic treatment

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

A Themed Issue in Honor of Prof. Dr. Fausto Catena—Outstanding Contributions in the Fields of Antibiotics in the Acute Care and Emergency

edited by Carlo Vallicelli

submission deadline 31 Jan 2026 | Viewed by 492 | Submission Open

Keywords: emergency surgery; intra-abdominal infections; antibiotic treatment; trauma surgery; sepsis

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Foodborne Pathogens: The Rise of Virulence and Antimicrobial Resistance

edited by

Luisa Brito

and

Acacio Salamandane

submission deadline 31 Jan 2026 | Viewed by 419 | Submission Open

Keywords: foodborne pathogens; antimicrobial resistance; virulence factors; food chain; antibiotic overuse; public health; food safety; zoonotic diseases; one health

A Themed Issue in Honor of Professor Aditya Gupta—Outstanding Contributions to Antifungal Therapy, Dermatology and Mycology

edited by Ditte Marie Saunte and Mesbah Talukder

submission deadline 31 Jan 2026 | Viewed by 387 | Submission Open

Keywords: onychomycosis; antifungal resistance; dermatophyte infections; antifungal stewardship; Trichophyton indotineae; topical and oral antifungals; treatment algorithms; epidemiology of onychomycosis

Molecular Diagnostics and Antimicrobial Resistance in Animal Pathogens

edited by Mariela E. Srednik and

Volker Krömker

submission deadline 31 Jan 2026 | Viewed by 347 | Submission Open

Keywords: antimicrobial susceptibility; molecular diagnostic; antimicrobial resistance; animal pathogens; bacterial diseases

(This special issue belongs to the Section Antibiotics in Animal Health)

Nanoparticles as Novel Solutions to Microbial Resistance in Hospital Care

edited by

Zdenka Bedlovičová

submission deadline 31 Jan 2026 | Viewed by 327 | Submission Open

Keywords: nanoparticles; antibiotic resistance; nosocomial infections; MRSA; VRSA; antimicrobial properties; multi-drug resistance

(This special issue belongs to the Section Antimicrobial Materials and Surfaces)

Advances in the Diagnosis and Antibiotic Treatments of Diabetic Foot Infections

edited by

Francisco Javier Álvaro-Afonso

and

Éric M. Senneville

submission deadline 31 Jan 2026 | Viewed by 281 | Submission Open

Keywords: diabetic foot; diabetic foot ulcer; diabetic foot osteomyelitis; antibiotics; treatment

Membrane Disruptors: The Role of Antimicrobial Peptides in Combatting Pathogens

edited by

Andrea Mescola

submission deadline 31 Jan 2026 | Viewed by 279 | Submission Open

Keywords: antimicrobial peptides (AMPs); microbial resistance; drug-resistant pathogens; anticancer; antiviral; membrane disruption; membrane poration; permeabilization; lipids; peptide design and engineering

(This special issue belongs to the Section Antimicrobial Peptides)

Antibiotic or Antibiotic Adjuvant Synthesis and Antimicrobial Evaluation, 2nd Edition

edited by

Jean Michel Brunel

submission deadline 31 Jan 2026 | Viewed by 245 | Submission Open

Keywords: antimicrobial agents; synergy; adjuvants; bacterial resistance

Antimicrobial Resistance (AMR) in the Food Chain: Detection Gaps and Mitigation Strategies

edited by

Joana Castro

António Machado

and

Ricardo Oliveira

submission deadline 31 Jan 2026 | Viewed by 229 | Submission Open

Keywords: antimicrobial resistance (AMR); foodborne pathogens; surveillance; detection methods; mitigation strategies; One Health

(This special issue belongs to the Section Antibiotics in Animal Health)

Epidemiology of Antimicrobial-Resistant Pathogens in Animals: A One Health Perspective

edited by

Francesco Pellegrini

Paolo Capozza

and

Marialaura Corrente

submission deadline 31 Jan 2026 | Viewed by 191 | Submission Open

Keywords: antimicrobial resistance (AMR); veterinary epidemiology; one health; zoonotic pathogens; surveillance systems; molecular epidemiology; resistance mechanisms

(This special issue belongs to the Section Antibiotics in Animal Health)

Antimicrobial Resistance in Bacterial Pathogens: Insights from Veterinary Medicine

edited by

Dimitris C. Chatzopoulos

submission deadline 31 Jan 2026 | Viewed by 139 | Submission Open

Keywords: antimicrobial resistance (AMR); veterinary medicine; One Health; animal health; zoonotic transmission; surveillance and monitoring

(This special issue belongs to the Section Antibiotics in Animal Health)

A Themed Issue in Honor of Prof. Jae-hyuk Yu—Antimicrobial Resistance in the Foodborne Pathogens

edited by

Hee-Soo Park

and Ahmad Alshannaq

submission deadline 1 Feb 2026 | 1 articles | Viewed by 1224 | Submission Open

Keywords: foodborne pathogens; antimicrobial resistance (AMR); food safety; antimicrobial preservation; food additives; antimicrobial resistance mechanisms

Bacterial Zoonotic Infections: Epidemiology, Virulence Mechanisms, Antimicrobial Resistance and Antibiotic Treatment

edited by

Rafael Vignoli

and Inés Bado

submission deadline 5 Feb 2026 | Viewed by 112 | Submission Open

Keywords: antimicrobial resistance; zoonotic bacteria; zoonotic infection; one health

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Livestock Antibiotic Use and Resistance

edited by Valentina Monistero,

Paola Cremonesi

Gloria Gioia

and Valerio Bronzo

submission deadline 15 Feb 2026 | 7 articles | Viewed by 32197 | Submission Open

Keywords: farm; livestock; antibiotic; antimicrobial resistance; One Health; multidrug-resistant; methicillin-resistant; extended-spectrum beta-lactamase; carbapenemase; superbug

(This special issue belongs to the Section Antibiotics in Animal Health)

Experimental Models and Novel Therapies for Difficult-to-Treat Biofilm-Associated Infections

edited by

Peng Gao

and

Xuan Li

submission deadline 15 Feb 2026 | 1 articles | Viewed by 477 | Submission Open

Keywords: biofilm-associated infections; antimicrobial resistance; experimental models (in vitro / in vivo); novel anti-biofilm therapies; antibiotic tolerance; combination therapy; antimicrobial peptides; phage therapy

Omics Approaches, Including Culturomics, for Assessing Antimicrobial Resistance in Bacterial Communities

edited by

Samantha Flores-Treviño

submission deadline 15 Feb 2026 | Viewed by 231 | Submission Open

Keywords: omics; culturomics; MALDI-TOF; antimicrobial resistance; gut microbiota

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Innovations in Antibacterial Agents: Combating Resistance, Improving Efficacy and Exploring New Mechanisms

edited by

Rok Frlan

and

Martina Hrast

submission deadline 20 Feb 2026 | 4 articles | Viewed by 13198 | Submission Open

Keywords: drug design; synthesis of novel antibacterial agents; computational chemistry; repurposing of drugs; novel antibacterial mechanisms

(This special issue belongs to the Section Novel Antimicrobial Agents)

Antimicrobial Resistance in Biofilm-Associated Infections

edited by

Fazlurrahman Khan

Nazia Tabassum

and

Young-Mog Kim

submission deadline 25 Feb 2026 | 5 articles | Viewed by 12355 | Submission Open

Keywords: biofilms; antimicrobial resistance; chronic infections; biofilm matrix; virulence factors; antibiotic efficacy; pathogen persistence; biofilm formation; medical implants; quorum sensing

(This special issue belongs to the Section Antibiofilm Strategies)

Feature Papers in Therapy of Diabetic Foot Infections

edited by

Ilker Uckay

and

Laura Soldevila

submission deadline 28 Feb 2026 | 11 articles | Viewed by 47098 | Submission Open

Keywords: diabetic foot infection; diabetic foot osteomyelitis; systemic antibiotic therapy; local antibiotic therapy; side effects; treatment success; antibiotic stewardship; antibiotic policies and difficulties

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Nanoparticles as Antibacterial/Antibiofilm Agents

edited by

J. Scott VanEpps

submission deadline 28 Feb 2026 | 9 articles | Viewed by 32151 | Submission Open

Keywords: nanoparticles; antibacterial; biofilm; mechanism; antibiotic resistance

(This special issue belongs to the Section Antimicrobial Materials and Surfaces)

Clinical Guidelines and Real Practice of Antimicrobial Pharmacotherapy

edited by

Darko Modun

submission deadline 28 Feb 2026 | 7 articles | Viewed by 21449 | Submission Open

Keywords: adverse drug reaction; patient adherence; antimicrobial resistance; clinical guidelines; clinical settings; regional factors; pharmacotherapy

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

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