Next Article in Journal / Special Issue
Nanoparticle-Integrated Hydrogels as Multifunctional Composite Materials for Biomedical Applications
Previous Article in Journal
Synthesis and Properties of New “Stimuli” Responsive Nanocomposite Hydrogels Containing Silver Nanoparticles
Previous Article in Special Issue
Composite Chitosan/Agarose Ferrogels for Potential Applications in Magnetic Hyperthermia
Article Menu

Export Article

Open AccessReview
Gels 2015, 1(2), 135-161; doi:10.3390/gels1020135

Magnetic Gel Composites for Hyperthermia Cancer Therapy

1
Institut für Organische Chemie, Universität Regensburg, Universitätsstr. 31, Regensburg 93040, Germany
2
IQAC-CSIC, Jordi Girona 18-26, Barcelona 08034, Spain
3
The Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Jordi Girona 18-26, Barcelona 08034, Spain
These authors contributed equally to this work.
*
Author to whom correspondence should be addressed.
Academic Editor: Rolando Barbucci
Received: 31 August 2015 / Accepted: 2 September 2015 / Published: 30 September 2015
(This article belongs to the Special Issue Nanoparticle-Hydrogel Composites for Biomedical Applications)
View Full-Text   |   Download PDF [7995 KB, uploaded 30 September 2015]   |  

Abstract

Hyperthermia therapy is a medical treatment based on the exposition of body tissue to slightly higher temperatures than physiological (i.e., between 41 and 46 °C) to damage and kill cancer cells or to make them more susceptible to the effects of radiation and anti-cancer drugs. Among several methods suitable for heating tumor areas, magnetic hyperthermia involves the introduction of magnetic micro/nanoparticles into the tumor tissue, followed by the application of an external magnetic field at fixed frequency and amplitude. A very interesting approach for magnetic hyperthermia is the use of biocompatible thermo-responsive magnetic gels made by the incorporation of the magnetic particles into cross-linked polymer gels. Mainly because of the hysteresis loss from the magnetic particles subjected to a magnetic field, the temperature of the system goes up and, once the temperature crosses the lower critical solution temperature, thermo-responsive gels undergo large volume changes and may deliver anti-cancer drug molecules that have been previously entrapped in their networks. This tutorial review describes the main properties and formulations of magnetic gel composites conceived for magnetic hyperthermia therapy. View Full-Text
Keywords: hydrogel; composites; magnetic nanoparticles; hyperthermia; cancer therapy; drug delivery hydrogel; composites; magnetic nanoparticles; hyperthermia; cancer therapy; drug delivery
Figures

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Häring, M.; Schiller, J.; Mayr, J.; Grijalvo, S.; Eritja, R.; Díaz, D.D. Magnetic Gel Composites for Hyperthermia Cancer Therapy. Gels 2015, 1, 135-161.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Gels EISSN 2310-2861 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top