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Gels 2015, 1(2), 162-178; doi:10.3390/gels1020162

Nanoparticle-Integrated Hydrogels as Multifunctional Composite Materials for Biomedical Applications

Dipartimento di Farmacia, Università di Napoli Federico II, Via D. Montesano 49, 80131 Napoli, Italy
Istituto per i Polimeri Compositi e Biomateriali (IPCB-CNR), P.le Tecchio 80, 80125 Napoli, Italy
Dipartimento Scienze Chimiche e Tecnologie dei Materiali (DSCTM-CNR), P.le Aldo Moro 7, 00185 Roma, Italy
These authors contributed equally to this work.
Author to whom correspondence should be addressed.
Academic Editor: Rolando Barbucci
Received: 3 July 2015 / Revised: 25 September 2015 / Accepted: 28 September 2015 / Published: 14 October 2015
(This article belongs to the Special Issue Nanoparticle-Hydrogel Composites for Biomedical Applications)
View Full-Text   |   Download PDF [1959 KB, uploaded 14 October 2015]   |  


This review focuses on the most recent developments in the field of nanocomposite hydrogels intended for biomedical applications. Nanocomposite hydrogels are hydrated polymeric networks with a physically or covalently crosslinked three-dimensional (3D) structure swollen with water, in the presence of nanoparticles or nanostructures. A wide array of nanomaterials (polymeric, carbon-based, metallic, ceramic) can be incorporated within the hydrogel network to obtain reinforced nanocomposite hydrogels. Nanocomposites represent a new class of materials with properties absent in the individual components. In particular, the incorporation of nanomaterials within a polymeric hydrogel network is an attractive approach to tailor the mechanical properties of the hydrogels and/or to provide the nanocomposite with responsiveness to external stimuli. View Full-Text
Keywords: nanocomposites; nanoparticles; hydrogels; biomedical applications; nanocomposite hydrogels nanocomposites; nanoparticles; hydrogels; biomedical applications; nanocomposite hydrogels

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Biondi, M.; Borzacchiello, A.; Mayol, L.; Ambrosio, L. Nanoparticle-Integrated Hydrogels as Multifunctional Composite Materials for Biomedical Applications. Gels 2015, 1, 162-178.

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