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J. Cardiovasc. Dev. Dis. 2016, 3(2), 11; doi:10.3390/jcdd3020011

The “Dead-End Tract” and Its Role in Arrhythmogenesis

Department of Clinical Electrophysiology, Erasmus Medical Center, Rotterdam, 3015 CE, The Netherlands
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Author to whom correspondence should be addressed.
Academic Editors: Andy Wessels, Robert E. Poelmann and Monique R.M. Jongbloed
Received: 27 November 2015 / Revised: 2 February 2016 / Accepted: 17 March 2016 / Published: 5 April 2016
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Abstract

Idiopathic outflow tract ventricular arrhythmias (VAs) represent a significant proportion of all VAs. The mechanism is thought to be catecholamine-mediated delayed after depolarizations and triggered activity, although other etiologies should be considered. In the adult cardiac conduction system it has been demonstrated that sometimes an embryonic branch, the so-called “dead-end tract”, persists beyond the bifurcation of the right and left bundle branch (LBB). Several findings suggest an involvement of this tract in idiopathic VAs (IVAs). The aim of this review is to summarize our current knowledge and the possible clinical significance of this tract. View Full-Text
Keywords: cardiac conduction system; dead-end tract; idiopathic ventricular arrhythmia cardiac conduction system; dead-end tract; idiopathic ventricular arrhythmia
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

de Vries, L.; Hendriks, A.; Szili-Torok, T. The “Dead-End Tract” and Its Role in Arrhythmogenesis. J. Cardiovasc. Dev. Dis. 2016, 3, 11.

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