Essential Oil from Piper aduncum: Chemical Analysis, Antimicrobial Assessment, and Literature Review
AbstractBackground: The challenge in antimicrobial chemotherapy is to find safe and selective agents with potency that will not be compromised by previously developed resistance. Terrestrial plants could provide new leads to antibacterial, antifungal, or antiprotozoal activity. Methods: The essential oil (EO) of Piper aduncum L. (Piperaceae) from Cuba was analyzed by gas chromatography—mass spectrometry (GC-MS). A cluster analysis of P. aduncum EO compositions reported in the literature was carried out. The EO was screened against a panel of microorganisms (bacteria, fungi, parasitic protozoa) as well as for cytotoxicity against human cells. In addition, a review of scientific literature and a bibliometric study was also conducted. Results: A total of 90 compounds were identified in the EO, of which camphor (17.1%), viridiflorol (14.5%), and piperitone (23.7%) were the main components. The cluster analysis revealed at least nine different chemotypes. The EO did not show notable activity against bacteria or fungi, but was active against parasitic protozoa. Conclusions: The results from this study indicate P. aduncum from Cuba is a unique chemotype, support the importance of P. aduncum EOs as medicines, and demonstrate the promise of Cuban P. aduncum EO as a chemotherapeutic agent against parasitic protozoal infections. View Full-Text
Scifeed alert for new publicationsNever miss any articles matching your research from any publisher
- Get alerts for new papers matching your research
- Find out the new papers from selected authors
- Updated daily for 49'000+ journals and 6000+ publishers
- Define your Scifeed now
Monzote, L.; Scull, R.; Cos, P.; Setzer, W.N. Essential Oil from Piper aduncum: Chemical Analysis, Antimicrobial Assessment, and Literature Review. Medicines 2017, 4, 49.
Monzote L, Scull R, Cos P, Setzer WN. Essential Oil from Piper aduncum: Chemical Analysis, Antimicrobial Assessment, and Literature Review. Medicines. 2017; 4(3):49.Chicago/Turabian Style
Monzote, Lianet; Scull, Ramón; Cos, Paul; Setzer, William N. 2017. "Essential Oil from Piper aduncum: Chemical Analysis, Antimicrobial Assessment, and Literature Review." Medicines 4, no. 3: 49.
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.