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Toxics, Volume 12, Issue 6

2024 June - 68 articles

Cover Story: Concern is emerging over organophosphate flame retardants (OPFRs), replacements for brominated flame retardants, for their developmental neurotoxic (DNT) potential due to their ubiquity, structural similarities to organophosphate pesticides and evidence from recent studies. Limited toxicity testing exists on the DNT potential of OPFRs due to challenges accompanying traditional in vivo DNT testing. Here, we employed an integrated approach to testing and assessment (IATA) using an extended battery of DNT in vitro assays and small model organisms that captures cellular processes involved in neurodevelopment and function. DNT potential from OPFRs was then related to human exposure using physiologically based toxicokinetic modeling to provide recommendations for risk assessment. View this paper
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Articles (68)

  • Opinion
  • Open Access
1,357 Views
4 Pages

20 June 2024

Since the early stages of the COVID-19 pandemic, there have been debates regarding the transmission modes of contagious viruses, including the influenza virus and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), along with its variants [...

(This article belongs to the Section Air Pollution and Health)
  • Article
  • Open Access
2 Citations
2,407 Views
16 Pages

The Olfactory Receptor Olfr25 Mediates Sperm Dysfunction Induced by Low-Dose Bisphenol A through the CatSper-Ca2+ Signaling Pathway

  • Jing Gu,
  • Ning Zhang,
  • Xiao Jiang,
  • Lei Zhu and ,
  • Yixia Lou,
  • Shengqi Sun,
  • Li Yin and
  • Jinyi Liu
  • + 3 authors+ 0 author

20 June 2024

Bisphenol A (BPA), a typical endocrine disruptor, is known to have various adverse effects on the male reproductive system. However, the toxic effects and mechanisms of low-dose BPA have not yet been fully explored. In this study, male Kunming mice w...

(This article belongs to the Section Reproductive and Developmental Toxicity)
  • Article
  • Open Access
10 Citations
4,304 Views
15 Pages

The GSTP1 rs1695 Polymorphism Is Associated with Mercury Levels and Neurodevelopmental Delay in Indigenous Munduruku Children from the Brazilian Amazon

  • Mayara Calixto da Silva,
  • Paulo Cesar Basta,
  • Cristina Barroso Hofer,
  • Mirian Akiko Furutani de Oliveira and ,
  • Joeseph William Kempton,
  • Rogério Adas Ayres de Oliveira,
  • Ana Claudia Santiago de Vasconcellos and
  • Jamila Alessandra Perini
  • + 3 authors+ 0 author

19 June 2024

Genetic polymorphisms may influence mercury (Hg) toxicity. The aims of this study were to evaluate individual factors, such as the presence of the GSTP1 rs1695 polymorphism, associated with internal Hg dose and child neurodevelopment in indigenous pe...

(This article belongs to the Section Metals and Radioactive Substances)
  • Article
  • Open Access
9 Citations
2,359 Views
14 Pages

19 June 2024

The adsorption of Sb(V) and As(V) onto iron-loaded gasification slag composite material (Fe-GFS), as well as the possible mechanisms, was investigated. Batch experiments showed that in a single system, Fe-GFS sorbed As(V) to a greater extent than Sb(...

(This article belongs to the Section Toxicity Reduction and Environmental Remediation)
  • Article
  • Open Access
14 Citations
4,817 Views
12 Pages

Macroplastic and Microparticle Pollution in Beach Sediments from Urias Coastal Lagoon (Northwest Mexico)

  • Daniela Alvarado-Zambrano,
  • José R. Rivera-Hernández and
  • Carlos Green-Ruiz

18 June 2024

This study investigates the occurrence and characteristics of macroplastic and polymer microparticles in the Urias coastal lagoon’s beach sediments, in northwest Mexico. Coastal lagoons, productive and vulnerable ecosystems, are impacted signif...

(This article belongs to the Special Issue Microplastic Pollution and Impact on Aquatic and Terrestrial Ecosystems)
  • Article
  • Open Access
12 Citations
3,925 Views
15 Pages

18 June 2024

The associations between VOCs and sex hormones in adolescents remain unclear, and the role of serum albumin in these associations deserves to be explored. We conducted cross-sectional analyses using generalized linear models (GLMs), weighted quantile...

(This article belongs to the Section Air Pollution and Health)
  • Article
  • Open Access
20 Citations
5,354 Views
26 Pages

Integrated Approach for Testing and Assessment for Developmental Neurotoxicity (DNT) to Prioritize Aromatic Organophosphorus Flame Retardants

  • Anna Kreutz,
  • Oluwakemi B. Oyetade,
  • Xiaoqing Chang,
  • Jui-Hua Hsieh and ,
  • Mamta Behl,
  • David G. Allen,
  • Nicole C. Kleinstreuer and
  • Helena T. Hogberg
  • + 3 authors+ 0 author

18 June 2024

Organophosphorus flame retardants (OPFRs) are abundant and persistent in the environment but have limited toxicity information. Their similarity in structure to organophosphate pesticides presents great concern for developmental neurotoxicity (DNT)....

(This article belongs to the Section Emerging Contaminants)
  • Article
  • Open Access
8 Citations
3,683 Views
14 Pages

The Legacy of Hg Contamination in a Past Mining Area (Tuscany, Italy): Hg Speciation and Health Risk Assessment

  • Simone Arrighi,
  • Fabrizio Franceschini,
  • Riccardo Petrini,
  • Silvia Fornasaro and
  • Lisa Ghezzi

16 June 2024

The mercury cell manufacturing process, which has been extensively used in chlor-alkali plants to produce chlorine and caustic soda by electrolysis, represents a major source of Hg environmental pollution. At Saline di Volterra (Tuscany, Italy), solu...

(This article belongs to the Section Ecotoxicology)
  • Article
  • Open Access
12 Citations
4,385 Views
17 Pages

Decontamination of Chlorpyrifos Residue in Soil by Using Mentha piperita (Lamiales: Lamiaceae) for Phytoremediation and Two Bacterial Strains

  • Ahmed A. A. Aioub,
  • Mohamed A. Fahmy,
  • Esraa E. Ammar,
  • Mohamed Maher and ,
  • Heba A. Ismail,
  • Jin Yue,
  • Qichun Zhang and
  • Sarah I. Z. Abdel-Wahab
  • + 3 authors+ 0 author

16 June 2024

This study utilizes Mentha piperita (MI) for the first time to investigate the uptake and translocation of chlorpyrifos (CPF; 10 µg g−1) from soil, introducing a new approach to improve the efficacy of this technique, which includes using...

(This article belongs to the Section Toxicity Reduction and Environmental Remediation)
  • Article
  • Open Access
8 Citations
2,432 Views
13 Pages

Construction of Immobilized Laccase System Based on ZnO and Degradation of Mesotrione

  • Wanlei Yue,
  • Xin Wang,
  • Jiale Zhang,
  • Jia Bao and
  • Mengqin Yao

16 June 2024

Mesotrione (MES) is a new environmental pollutant. Some reports have indicated that microbial enzymes could be utilized for MES degradation. Laccase is a green biocatalyst whose potential use in environmental pollutant detoxification has been conside...

(This article belongs to the Section Toxicity Reduction and Environmental Remediation)
  • Review
  • Open Access
29 Citations
11,984 Views
22 Pages

14 June 2024

Physiologically based pharmacokinetic/toxicokinetic (PBPK/PBTK) models are designed to elucidate the mechanism of chemical compound action in organisms based on the physiological, biochemical, anatomical, and thermodynamic properties of organisms. Af...

(This article belongs to the Section Exposome Analysis and Risk Assessment)
  • Article
  • Open Access
2 Citations
2,758 Views
26 Pages

Using the Multicomponent Aerosol FORmation Model (MAFOR) to Determine Improved VOC Emission Factors in Ship Plumes

  • Lea Fink,
  • Matthias Karl,
  • Volker Matthias,
  • Andreas Weigelt and ,
  • Matti Irjala and
  • Pauli Simonen
  • + 1 author+ 0 author

14 June 2024

International shipping’s particulate matter primary emissions have a share in global anthropogenic emissions of between 3% and 4%. Ship emissions of volatile organic compounds (VOCs) can play an important role in the formation of fine particula...

(This article belongs to the Section Air Pollution and Health)
  • Article
  • Open Access
7 Citations
3,018 Views
17 Pages

Citric Acid Inhibits Cd Absorption and Transportation by Improving the Antagonism of Essential Elements in Rice Organs

  • Kexin Chen,
  • Bozhen Yu,
  • Weijie Xue,
  • Yuebing Sun and ,
  • Changbo Zhang,
  • Xusheng Gao,
  • Xiaojia Zhou,
  • Yun Deng,
  • Jiarun Yang and
  • Boqian Zhang
  • + 5 authors+ 0 author

14 June 2024

Excessive cadmium (Cd) in rice is a global environmental problem. Therefore, reducing Cd content in rice is of great significance for ensuring food security and human health. A field experiment was conducted to study the effects of foliar application...

(This article belongs to the Special Issue Transformation Process and Toxic Effects of Pollutants in Agricultural Environment)
  • Article
  • Open Access
11 Citations
4,171 Views
14 Pages

Associations of Urinary Heavy Metal Mixtures with High Remnant Cholesterol among US Adults: Evidence from the National Health and Nutrition Examination Survey (1998–2018)

  • Hui Li,
  • Bei-Jing Cheng,
  • Pei-Yan Yang,
  • Chun Wang and ,
  • Ke Meng,
  • Tian-Lin Li,
  • Jia Wang and
  • Ran Liu
  • + 3 authors+ 0 author

13 June 2024

The main objective of our study is to explore the associations between combined exposure to urinary heavy metals and high remnant cholesterol (HRC), a known cardiovascular risk factor. Utilizing data from the National Health and Nutrition Examination...

(This article belongs to the Section Exposome Analysis and Risk Assessment)
  • Article
  • Open Access
8 Citations
3,917 Views
14 Pages

Navigating a Microplastic Sea: How the Pacific Cupped Oyster (Magallana gigas) Respond to Microplastic Pollution in Lagoons

  • Gianluca De Rinaldis,
  • Paolo Pastorino,
  • Tommaso Scirocco,
  • Claudia Sacchetti and ,
  • Serena Anselmi,
  • Francesca Provenza,
  • Monia Renzi and
  • Antonietta Specchiulli
  • + 3 authors+ 0 author

13 June 2024

Microplastic pollution poses an escalating concern, particularly in coastal lagoons rich in biodiversity. This study delved into the occurrence of microplastics (MPs) in Magallana gigas (formerly Crassostrea gigas) from the Orbetello and Varano coast...

(This article belongs to the Special Issue Microplastic Pollution and Impact on Aquatic and Terrestrial Ecosystems)
  • Article
  • Open Access
15 Citations
5,367 Views
17 Pages

Health Impacts of Natural Background Radiation in High Air Pollution Area of Thailand

  • Narongchai Autsavapromporn,
  • Chutima Kranrod,
  • Rawiwan Kritsananuwat,
  • Phachirarat Sola and ,
  • Pitchayaponne Klunklin,
  • Imjai Chitapanarux,
  • Churdsak Jaikang,
  • Tawachai Monum,
  • Masahiro Hosoda and
  • Shinji Tokonami
  • + 5 authors+ 0 author

13 June 2024

Chiang Mai province of Thailand is known for having the highest natural background radiation in the country, as well as being recognized as one of the world’s most polluted cities for air quality. This represents the major contributor to the de...

(This article belongs to the Special Issue Radiation: Occurrence, Transport and Effect)
  • Article
  • Open Access
7 Citations
2,881 Views
14 Pages

Esketamine Exposure Impairs Cardiac Development and Function in Zebrafish Larvae

  • Shuo Huang,
  • Jingyi Wang,
  • Tingting Lin,
  • Chengyong He and
  • Zhiyuan Chen

13 June 2024

Esketamine is a widely used intravenous general anesthetic. However, its safety, particularly its effects on the heart, is not fully understood. In this study, we investigated the effects of esketamine exposure on zebrafish embryonic heart developmen...

(This article belongs to the Section Reproductive and Developmental Toxicity)
  • Communication
  • Open Access
1 Citations
3,122 Views
10 Pages

Exploring Heavy Metal and Metalloid Exposure in Children: A Pilot Biomonitoring Study near a Sugarcane Mill

  • Oliver Mendoza-Cano,
  • Agustin Lugo-Radillo,
  • Mónica Ríos-Silva,
  • Irma Elizabeth Gonzalez-Curiel and ,
  • Jaime Alberto Bricio-Barrios,
  • Arlette A. Camacho-delaCruz,
  • María Fernanda Romo-García,
  • Herguin Benjamín Cuevas-Arellano,
  • Ana Luz Quintanilla-Montoya and
  • Efrén Murillo-Zamora
  • + 11 authors+ 6 authors

12 June 2024

Sugarcane production has been linked to the release of heavy metals and metalloids (HM/MTs) into the environment, raising concerns about potential health risks. This study aimed to assess the levels of 19 HM/MTs in children living near a sugarcane mi...

(This article belongs to the Section Metals and Radioactive Substances)
  • Article
  • Open Access
7 Citations
3,441 Views
9 Pages

Models for the No-Observed-Effect Concentration (NOEC) and Maximal Half-Effective Concentration (EC50)

  • Nadia Iovine,
  • Alla P. Toropova,
  • Andrey A. Toropov,
  • Alessandra Roncaglioni and
  • Emilio Benfenati

12 June 2024

Typical in silico models for ecotoxicology focus on a few endpoints, but there is a need to increase the diversity of these models. This study proposes models using the NOEC for the harlequin fly (Chironomus riparius) and EC50 for swollen duckweed (L...

(This article belongs to the Section Novel Methods in Toxicology Research)
  • Communication
  • Open Access
4 Citations
3,035 Views
9 Pages

The Development of a Rapid, Cost-Effective, and Green Analytical Method for Mercury Speciation

  • Patrícia Cristina Costa Ladeira,
  • Caroline Cristine Augusto,
  • Bruno Alves Rocha,
  • Jairo Lisboa Rodrigues and ,
  • Giovanna de Fátima Moreno Aguiar and
  • Bruno Lemos Batista
  • + 1 author+ 0 author

11 June 2024

Mercury is a naturally occurring metal found in various inorganic and organic forms within the environment. Due to its high toxicity, there is global concern regarding human exposure to this element. The combination of high-performance liquid chromat...

(This article belongs to the Section Novel Methods in Toxicology Research)
  • Article
  • Open Access
6 Citations
2,331 Views
14 Pages

Shift in Bacterial Community Structure in the Biodegradation of Benzene and Toluene under Sulfate-Reducing Condition

  • Zhengwei Liu,
  • Xiaoyu Lin,
  • Xinzhe Wang,
  • Mingbo Sun and ,
  • Shici Ma and
  • Shucai Zhang
  • + 1 author+ 0 author

10 June 2024

Groundwater contaminated by benzene and toluene is a common issue, posing a threat to the ecosystems and human health. The removal of benzene and toluene under sulfate-reducing condition is well known, but how the bacterial community shifts during th...

(This article belongs to the Special Issue Environmental Transport and Transformation of Pollutants)
  • Article
  • Open Access
18 Citations
4,707 Views
22 Pages

Characterization of Wildland Firefighters’ Exposure to Coarse, Fine, and Ultrafine Particles; Polycyclic Aromatic Hydrocarbons; and Metal(loid)s, and Estimation of Associated Health Risks

  • Joana Teixeira,
  • Gabriel Sousa,
  • Rui Azevedo,
  • Agostinho Almeida and ,
  • Cristina Delerue-Matos,
  • Xianyu Wang,
  • Alice Santos-Silva,
  • Francisca Rodrigues and
  • Marta Oliveira
  • + 4 authors+ 0 author

10 June 2024

Firefighters’ occupational activity causes cancer, and the characterization of exposure during firefighting activities remains limited. This work characterizes, for the first time, firefighters’ exposure to (coarse/fine/ultrafine) particu...

(This article belongs to the Special Issue Firefighters’ Occupational Exposures and Health Risks)
  • Review
  • Open Access
5 Citations
6,875 Views
13 Pages

Inflammatory Bowel Disease Therapies and Acute Liver Injury

  • Roberto Catanzaro,
  • Francesco Marotta,
  • Azam Yazdani and
  • Morena Sciuto

8 June 2024

Drug-induced liver disease (DILI) represents one of the main problems in the therapeutic field. There are several non-modifiable risk factors, such as age and sex, and all drugs can cause hepatotoxicity of varying degrees, including those for the tre...

(This article belongs to the Section Drugs Toxicity)
  • Article
  • Open Access
24 Citations
2,567 Views
13 Pages

7 June 2024

Transgenerational nanoplastic toxicity could be detected in Caenorhabditis elegans after exposure at the parental generation (P0-G); however, the underlying mechanisms remain largely unclear. We aimed to examine the role of germline nuclear hormone r...

(This article belongs to the Section Exposome Analysis and Risk Assessment)
  • Article
  • Open Access
14 Citations
3,658 Views
17 Pages

Effective Technique and Mechanism for Simultaneous Adsorption of As(III/V) from Wastewater by Fe-ZIF-8@MXene

  • Shuyan Zang,
  • Qing Zhang,
  • Baoli Hu,
  • Yaqian Zhang and ,
  • Jaan H. Pu and
  • Meiheng Lv
  • + 1 author+ 0 author

7 June 2024

Arsenic (As) contamination of surface water has become a global concern, especially for the third world countries, and it is imperative to develop advanced materials and an effective treatment method to address the issue. In this paper, iron doped ZI...

(This article belongs to the Section Toxicity Reduction and Environmental Remediation)
  • Article
  • Open Access
3 Citations
1,973 Views
12 Pages

Effects of Foliar Spraying of Dicarboxylicdimethylammonium Chloride on Cadmium and Arsenic Accumulation in Rice Grains

  • Lin Fu,
  • Jiawei Deng,
  • Dayliana Ruiz Lao,
  • Changbo Zhang and ,
  • Weijie Xue,
  • Yun Deng and
  • Xin Luo
  • + 2 authors+ 0 author

7 June 2024

A field experiment with double cropping rice was carried out to study the foliar application effects of dicarboxylicdimethylammonium chloride (DDAC) on cadmium (Cd) and arsenic (As) accumulation in rice grains. The results showed that the spraying of...

(This article belongs to the Special Issue Transformation Process and Toxic Effects of Pollutants in Agricultural Environment)
  • Article
  • Open Access
1 Citations
2,568 Views
11 Pages

Mercury Dynamics in the Sea of Azov: Insights from a Mass Balance Model

  • Christoph Gade,
  • Rebecca von Hellfeld,
  • Lenka Mbadugha and
  • Graeme Paton

7 June 2024

The Sea of Azov, an inland shelf sea bounding Ukraine and Russia, experiences the effects of ongoing and legacy pollution. One of the main contaminants of concern is the heavy metal mercury (Hg), which is emitted from the regional coal industry, form...

(This article belongs to the Section Ecotoxicology)
  • Article
  • Open Access
12 Citations
9,489 Views
12 Pages

The Concentration of Benzo[a]pyrene in Food Cooked by Air Fryer and Oven: A Comparison Study

  • Xiaoxin Chen,
  • Yingxin Liao,
  • Baiwen Lin,
  • Xing He and ,
  • Sibei Li,
  • Chenghui Zhong,
  • Saifeng Li,
  • Yun Zhou and
  • Lieyang Fan
  • + 4 authors+ 0 author

6 June 2024

The air fryer utilizes heated air rather than hot oil to achieve frying, eliminating the need for cooking oil, rendering it a healthier cooking method than traditional frying and baking. However, there is limited evidence supporting that the air frye...

(This article belongs to the Section Air Pollution and Health)
  • Review
  • Open Access
18 Citations
5,490 Views
29 Pages

Non-Steroidal Anti-Inflammatory Drugs in the Aquatic Environment and Bivalves: The State of the Art

  • Pedro Pires,
  • André M. P. T. Pereira,
  • Angelina Pena and
  • Liliana J. G. Silva

5 June 2024

In recent years, contaminants of emerging concern have been reported in several environmental matrices due to advances in analytical methodologies. These anthropogenic micropollutants are detected at residual levels, representing an ecotoxicological...

(This article belongs to the Section Emerging Contaminants)
  • Article
  • Open Access
14 Citations
4,947 Views
11 Pages

5 June 2024

Hermetia illucens larvae can use organic wastes as a substrate, which makes them an interesting potential feed. However, waste may contain heavy metals, which are limited in feed. Here, we investigated the ability of H. illucens to grow on organic wa...

(This article belongs to the Special Issue Bioremediation of Pollutants in Sewage Sludge)
  • Article
  • Open Access
4 Citations
2,336 Views
14 Pages

5 June 2024

The bioaccessibility of particle-bound hydrophobic organic contaminants, such as polycyclic aromatic hydrocarbons (PAHs), and the factors influencing their re-release are crucial for assessing potential human health risks via inhalation and hand-mout...

(This article belongs to the Section Exposome Analysis and Risk Assessment)
  • Article
  • Open Access
6 Citations
2,156 Views
16 Pages

Degradation of Sodium Acetate by Catalytic Ozonation Coupled with MnOx/NiOOH-Modified Fly Ash

  • Ruifu Chen,
  • Hao Zhang,
  • Shengyu Shao,
  • Huajun Xu and ,
  • Kaicheng Zhou,
  • Yinzhi Jiang and
  • Pengfei Sun
  • + 2 authors+ 0 author

4 June 2024

Fly ash, a type of solid waste generated in power plants, can be utilized as a catalyst carrier to enhance its value-added potential. Common methods often involve using a large amount of alkali for preprocessing, resulting in stable quartz and mullit...

(This article belongs to the Section Toxicity Reduction and Environmental Remediation)
  • Article
  • Open Access
7 Citations
2,806 Views
13 Pages

Antibiotics in Surface Sediments from the Anning River in Sichuan Province, China: Occurrence, Distribution, and Risk Assessment

  • Junlie Zhou,
  • Jianglin Kang,
  • Chunyan Lin,
  • Qi Xu and ,
  • Wanrong Yang,
  • Ke Fan and
  • Jinrong Li
  • + 2 authors+ 0 author

4 June 2024

The occurrence, distribution, and ecological risk assessment of 36 antibiotics from five groups, including macrolides (MLs), fluoroquinolones (FQs), tetracyclines (TCs), amphenicols (APs), and sulfonamides (SAs), were investigated for the first time...

(This article belongs to the Section Emerging Contaminants)
  • Article
  • Open Access
17 Citations
3,348 Views
16 Pages

Chronic Lead Exposure in Adult Mice: Associations with miR-671/CDR1as Regulation, NF-κB Signaling, and Alzheimer’s Disease-like Pathology

  • Mengyun Qiao,
  • Haitao Yang,
  • Li Liu,
  • Tao Yu and ,
  • Haihua Wang,
  • Xiao Chen,
  • Yi Zhang,
  • Airu Duan,
  • Shujun Lyu and
  • Bin Li
  • + 7 authors+ 2 authors

4 June 2024

Long-term exposure to lead (Pb) can result in chronic damage to the body through accumulation in the central nervous system (CNS) leading to neurodegenerative diseases, such as Alzheimer’s disease (AD). This study delves into the intricate role...

(This article belongs to the Section Human Toxicology and Epidemiology)
  • Article
  • Open Access
5 Citations
3,045 Views
12 Pages

Leukocyte Telomere Length Mediates the Associations between Blood Lead and Cadmium with Hypertension among Adults in the United States: A Cross-Sectional Study

  • Changping Ouyang,
  • Yinan Yang,
  • Jinhua Pan,
  • Heming Liu and ,
  • Xuemei Wang,
  • Shengze Zhou,
  • Xiaoru Shi,
  • Yanxia Zhang,
  • Dan Wang and
  • Xiaobin Hu
  • + 5 authors+ 0 author

3 June 2024

There is evidence to support the links between lead and cadmium exposure with hypertension and also with leukocyte telomere length (LTL). The objective of this study is to investigate the role that LTL may play in the relationship between lead and ca...

(This article belongs to the Special Issue Traditional and Emerging Pollutants: Human Exposure Profiles and Health Effects)
  • Article
  • Open Access
14 Citations
3,443 Views
11 Pages

Microfibers in the Diet of a Highly Aerial Bird, the Common Swift Apus apus

  • Alessandra Costanzo,
  • Roberto Ambrosini,
  • Milo Manica,
  • Daniela Casola and ,
  • Carlo Polidori,
  • Valentina Gianotti,
  • Eleonora Conterosito,
  • Maddalena Roncoli,
  • Marco Parolini and
  • Beatrice De Felice
  • + 5 authors+ 0 author

3 June 2024

Microplastic pollution is a pervasive global issue affecting various ecosystems. Despite the escalating production and well-documented contamination in both aquatic and terrestrial environments, the research focused on airborne microplastics and thei...

(This article belongs to the Special Issue Microplastic Pollution and Impact on Aquatic and Terrestrial Ecosystems)
  • Article
  • Open Access
1 Citations
2,465 Views
14 Pages

TBHQ Alleviates Particulate Matter-Induced Pyroptosis in Human Nasal Epithelial Cells

  • Ji-Sun Kim,
  • Hyunsu Choi,
  • Jeong-Min Oh,
  • Sung Won Kim and ,
  • Soo Whan Kim,
  • Byung Guk Kim,
  • Jin Hee Cho,
  • Joohyung Lee and
  • Dong Chang Lee
  • + 4 authors+ 0 author

3 June 2024

Pyroptosis represents a type of cell death mechanism notable for its cell membrane disruption and the subsequent release of proinflammatory cytokines. The Nod-like receptor family pyrin domain containing inflammasome 3 (NLRP3) plays a critical role i...

(This article belongs to the Special Issue Air Pollutant Exposure and Respiratory Diseases)
  • Article
  • Open Access
12 Citations
2,909 Views
18 Pages

3 June 2024

The management of plant-parasitic nematodes (PPNs) still relies on traditional nematicides that threaten the environment and human health. Novel solutions are urgently needed for PPN pest management that are effective while safeguarding non-target or...

  • Article
  • Open Access
8 Citations
3,322 Views
24 Pages

Advanced Photocatalytic Degradation of Cytarabine from Pharmaceutical Wastewaters

  • Alexandra Berbentea,
  • Mihaela Ciopec,
  • Narcis Duteanu,
  • Adina Negrea and ,
  • Petru Negrea,
  • Nicoleta Sorina Nemeş,
  • Bogdan Pascu,
  • Paula Svera (m. Ianasi),
  • Cătălin Ianăşi and
  • Estera Boeriu
  • + 7 authors+ 2 authors

31 May 2024

The need to develop advanced wastewater treatment techniques and their use has become a priority, the main goal being the efficient removal of pollutants, especially those of organic origin. This study presents the photo-degradation of a pharmaceutic...

(This article belongs to the Special Issue Techniques and Methods for Toxic Agent Analysis and Removal)
  • Article
  • Open Access
1 Citations
2,741 Views
14 Pages

31 May 2024

To understand the influences of emulsified fuel on ship exhaust emissions more comprehensively, the emissions of particulate matter (PM), nitrated, oxygenated and parent polycyclic aromatic hydrocarbons (PAHs) were studied on a ship main engine burni...

  • Article
  • Open Access
20 Citations
6,484 Views
23 Pages

Non-Targeted PFAS Suspect Screening and Quantification of Drinking Water Samples Collected through Community Engaged Research in North Carolina’s Cape Fear River Basin

  • Rebecca A. Weed,
  • Grace Campbell,
  • Lacey Brown,
  • Katlyn May and ,
  • Dana Sargent,
  • Emily Sutton,
  • Kemp Burdette,
  • Wayne Rider,
  • Erin S. Baker and
  • Jeffrey R. Enders
  • + 5 authors+ 0 author

31 May 2024

A community engaged research (CER) approach was used to provide an exposure assessment of poly- and perfluorinated (PFAS) compounds in North Carolina residential drinking water. Working in concert with community partners, who acted as liaisons to loc...

(This article belongs to the Special Issue Per- and Polyfluoroalkyl Substances in the Environment: Sources, Fate and Risk Assessments)
  • Article
  • Open Access
3 Citations
3,037 Views
16 Pages

Biotransformation of Chlorpyrifos Shewanella oneidensis MR-1 in the Presence of Goethite: Experimental Optimization and Degradation Products

  • Shen Tang,
  • Yanhong Li,
  • Zongqiang Zhu,
  • Yaru Wang and ,
  • Yuqing Peng,
  • Jing Zhang,
  • Peijie Nong,
  • Shufen Pan,
  • Yinming Fan and
  • Yinian Zhu
  • + 5 authors+ 0 author

31 May 2024

In this study, the degradation system of Shewanella oneidensis MR-1 and goethite was constructed with chlorpyrifos as the target contaminant. The effects of initial pH, contaminant concentration, and temperature on the removal rate of chlorpyrifos du...

(This article belongs to the Topic Removal of Hazardous Substances from Water Resources)
  • Article
  • Open Access
6 Citations
4,275 Views
15 Pages

An In Vitro Human Skin Test for Predicting Skin Sensitization and Adverse Immune Reactions to Biologics

  • Shaheda Sameena Ahmed,
  • Mohammed Mahid Ahmed,
  • Abbas Ishaq,
  • Matthew Freer and ,
  • Richard Stebbings and
  • Anne Mary Dickinson
  • + 1 author+ 0 author

30 May 2024

Biologics, including monoclonal antibodies (mAb), have proved to be effective and successful therapeutic agents, particularly in the treatment of cancer and immune-inflammatory conditions, as well as allergies and infections. However, their use carri...

(This article belongs to the Special Issue Skin Sensitization Testing Using New Approach Methodologies)
  • Review
  • Open Access
53 Citations
8,272 Views
20 Pages

The Easily Overlooked Effect of Global Warming: Diffusion of Heavy Metals

  • Wenqi Xiao,
  • Yunfeng Zhang,
  • Xiaodie Chen,
  • Ajia Sha and ,
  • Zhuang Xiong,
  • Yingyong Luo,
  • Lianxin Peng,
  • Liang Zou,
  • Changsong Zhao and
  • Qiang Li
  • + 5 authors+ 0 author

30 May 2024

Since industrialization, global temperatures have continued to rise. Human activities have resulted in heavy metals being freed from their original, fixed locations. Because of global warming, glaciers are melting, carbon dioxide concentrations are i...

(This article belongs to the Section Metals and Radioactive Substances)
  • Article
  • Open Access
19 Citations
5,757 Views
14 Pages

Multi-Omics Analysis Reveals the Toxicity of Polyvinyl Chloride Microplastics toward BEAS-2B Cells

  • Chengzhi Liu,
  • Shuang Chen,
  • Jiangliang Chu,
  • Yifan Yang and ,
  • Beilei Yuan and
  • Huazhong Zhang
  • + 1 author+ 0 author

30 May 2024

Polyvinyl chloride microplastics (PVC-MPs) are microplastic pollutants widely present in the environment, but their potential risks to human lung health and underlying toxicity mechanisms remain unknown. In this study, we systematically analyzed the...

(This article belongs to the Special Issue State-of-the-Art Environmental Chemicals Exposomics and Metabolomics)
  • Article
  • Open Access
7 Citations
2,408 Views
13 Pages

Association of Prenatal Dietary Toxicants and Inorganic Arsenic Exposure with Children’s Emotional and Behavioral Problems: ECLIPSES Study

  • Xiruo Kou,
  • Josefa Canals,
  • Monica Bulló,
  • Nerea Becerra-Tomás and ,
  • Cristina Jardí and
  • Victoria Arija
  • + 1 author+ 0 author

29 May 2024

Prenatal exposure to dietary toxicants is linked to neurocognitive issues, but its effect on early emotional and behavioral development in children is less clear. To explore the relationship between prenatal intake of As, iAs, Cd, MeHg, Pb, PCDD/Fs,...

(This article belongs to the Section Agrochemicals and Food Toxicology)
  • Review
  • Open Access
14 Citations
3,223 Views
14 Pages

29 May 2024

In agriculture, diphenyl ether herbicides are a broad-spectrum family of pesticides mainly used to control annual weeds in agriculture. Although diphenyl ether herbicides have a long-lasting effect in weed control, they can also be harmful to succeed...

(This article belongs to the Special Issue Ecotoxicity Induced by Pesticides Exposure Volume II)
  • Article
  • Open Access
16 Citations
2,880 Views
15 Pages

miR-21-Mediated Endothelial Senescence and Dysfunction Are Involved in Cigarette Smoke-Induced Pulmonary Hypertension through Activation of PI3K/AKT/mTOR Signaling

  • Bin He,
  • Binxia Shao,
  • Cheng Cheng,
  • Zitong Ye and ,
  • Yi Yang,
  • Bowen Fan,
  • Haibo Xia,
  • Hao Wu,
  • Qizhan Liu and
  • Jinsong Zhang
  • + 5 authors+ 0 author

29 May 2024

Smoking is a pathogenic factor for pulmonary hypertension (PH). Our previous study showed that serum miR-21 levels are elevated in smokers. miR-21 is considered as engaged in the PH process; however, its mechanisms remain unclear. In this investigati...

(This article belongs to the Section Human Toxicology and Epidemiology)
  • Article
  • Open Access
15 Citations
3,804 Views
19 Pages

High-Coverage UHPLC-MS/MS Analysis of 67 Mycotoxins in Plasma for Male Infertility Exposure Studies

  • Xiao Ning,
  • Lulu Wang,
  • Jia-Sheng Wang,
  • Jian Ji and ,
  • Shaoming Jin,
  • Jiadi Sun,
  • Yongli Ye,
  • Shenghui Mei,
  • Yinzhi Zhang and
  • Xiulan Sun
  • + 6 authors+ 1 author

28 May 2024

Mycotoxins are a class of exogenous metabolites that are major contributors to foodborne diseases and pose a potential threat to human health. However, little attention has been paid to trace mycotoxin co-exposure situations in vivo. To address this,...

(This article belongs to the Special Issue State-of-the-Art Environmental Chemicals Exposomics and Metabolomics)
  • Perspective
  • Open Access
34 Citations
8,037 Views
11 Pages

A Review of N-(1,3-Dimethylbutyl)-N′-phenyl-p-Phenylenediamine (6PPD) and Its Derivative 6PPD-Quinone in the Environment

  • Yi Li,
  • Jingjing Zeng,
  • Yongjin Liang,
  • Yanlong Zhao and ,
  • Shujun Zhang,
  • Zhongyan Chen,
  • Jiawen Zhang,
  • Xingze Shen,
  • Jiabin Wang and
  • Yuxin Sun
  • + 6 authors+ 1 author

28 May 2024

As an antioxidant and antiozonant, N-(1,3-Dimethylbutyl)-N′-phenyl-p-phenylenediamine (6PPD) is predominantly used in the rubber industry to prevent degradation. However, 6PPD can be ozonated to generate a highly toxic transformation product ca...

(This article belongs to the Section Emerging Contaminants)

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Toxics - ISSN 2305-6304