Aptamer-Based Electrochemical Sensing of Lysozyme
AbstractProtein analysis and quantification are required daily by thousands of laboratories worldwide for activities ranging from protein characterization to clinical diagnostics. Multiple factors have to be considered when selecting the best detection and quantification assay, including the amount of protein available, its concentration, the presence of interfering molecules, as well as costs and rapidity. This is also the case for lysozyme, a 14.3-kDa protein ubiquitously present in many organisms, that has been identified with a variety of functions: antibacterial activity, a biomarker of several serious medical conditions, a potential allergen in foods or a model of amyloid-type protein aggregation. Since the design of the first lysozyme aptamer in 2001, lysozyme became one of the most intensively-investigated biological target analytes for the design of novel biosensing concepts, particularly with regards to electrochemical aptasensors. In this review, we discuss the state of the art of aptamer-based electrochemical sensing of lysozyme, with emphasis on sensing in serum and real samples. View Full-Text
Share & Cite This Article
Vasilescu, A.; Wang, Q.; Li, M.; Boukherroub, R.; Szunerits, S. Aptamer-Based Electrochemical Sensing of Lysozyme. Chemosensors 2016, 4, 10.
Vasilescu A, Wang Q, Li M, Boukherroub R, Szunerits S. Aptamer-Based Electrochemical Sensing of Lysozyme. Chemosensors. 2016; 4(2):10.Chicago/Turabian Style
Vasilescu, Alina; Wang, Qian; Li, Musen; Boukherroub, Rabah; Szunerits, Sabine. 2016. "Aptamer-Based Electrochemical Sensing of Lysozyme." Chemosensors 4, no. 2: 10.
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.