A Quality Control Assay to Access the HCl Molarity of Radionuclide Solutions
AbstractStrontium-82 is produced by proton activation of a rubidium chloride target in an accelerator or cyclotron and purified by ion exchange chromatography. The Strontrium-82 is used in Cardigen generators to produce Rubidium-82 for cardiac imaging. Quality control testing of the purified Strontium-82 is performed with Inductively Coupled Plasma-Optical Emission spectroscopy (ICP-OES) and gamma spectroscopy. To meet Department of Energy specifications for HCl molarity the purified Strontium-82 solution needs to be tested to determine if the isotope is in the 0.05–0.5 M HCl range. This manuscript reports a simple HCl molarity test to determine if the purified Strontium-82 solution meets specifications. Validation of the assay was performed by evaluating all solutions associate with Strontium-82 processing. View Full-Text
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Fitzsimmons, J. A Quality Control Assay to Access the HCl Molarity of Radionuclide Solutions. Chemosensors 2016, 4, 9.
Fitzsimmons J. A Quality Control Assay to Access the HCl Molarity of Radionuclide Solutions. Chemosensors. 2016; 4(2):9.Chicago/Turabian Style
Fitzsimmons, Jonathan. 2016. "A Quality Control Assay to Access the HCl Molarity of Radionuclide Solutions." Chemosensors 4, no. 2: 9.