Inhibitory Effect of b-AP15 on the 20S Proteasome
AbstractThe 26S proteasome is a cellular proteolytic complex containing 19S regulatory particles and the 20S core proteasome. It was reported that the small molecule b-AP15 targets the proteasome by inhibiting deubiquitination of the 19S regulatory particles of the proteasome complex. An investigation of b-AP15 on the 20S proteasome core suggested that this compound can also inhibit the 20S proteasome with a potency equivalent to that found to inhibit the 19S regulatory particles. View Full-Text
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Huang, L.; Jung, K.; Chen, C.H. Inhibitory Effect of b-AP15 on the 20S Proteasome. Biomolecules 2014, 4, 931-939.
Huang L, Jung K, Chen CH. Inhibitory Effect of b-AP15 on the 20S Proteasome. Biomolecules. 2014; 4(4):931-939.Chicago/Turabian Style
Huang, Li; Jung, Katherine; Chen, Chin H. 2014. "Inhibitory Effect of b-AP15 on the 20S Proteasome." Biomolecules 4, no. 4: 931-939.