Proteasome- and Ethanol-Dependent Regulation of HCV-Infection Pathogenesis
Abstract
:1. HCV, the Proteasome and Oxidative Stress
2. The Proteasome-Dependent Regulation of HCV Propagation
3. The Proteasome and HCV-Dependent Evasion of Viral Clearance
4. Summary and Conclusions
Abbreviations
HCV | hepatitis C virus |
NS5A | non-structural protein 5 A |
IFN | interferon |
CYP 2E1 | cytochrome P450 2E1 |
IPR | immunoproteasome |
LMP7 | hepatitis C virus |
HCV | low molecular mass polypeptide-7 |
PA28 | the proteasome activator complex subunit 1 |
PAMP | pathogen-associated molecular pattern |
ISG15 | ISG15 |
RIG-1 | retinoic acid-inducible gene 1 |
Jak-STAT1 | Janus kinase-signal transducer and activator of transcription-1 |
MAVS | mitochondrial antiviral signaling protein |
PP2A | protein phosphatase 2A |
PRMT-1 | protein arginine N-methyltransferase 1 |
Acknowledgments
Conflicts of Interest
References
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Osna, N.A.; Ganesan, M.; Donohue, T.M., Jr. Proteasome- and Ethanol-Dependent Regulation of HCV-Infection Pathogenesis. Biomolecules 2014, 4, 885-896. https://doi.org/10.3390/biom4040885
Osna NA, Ganesan M, Donohue TM Jr. Proteasome- and Ethanol-Dependent Regulation of HCV-Infection Pathogenesis. Biomolecules. 2014; 4(4):885-896. https://doi.org/10.3390/biom4040885
Chicago/Turabian StyleOsna, Natalia A., Murali Ganesan, and Terrence M. Donohue, Jr. 2014. "Proteasome- and Ethanol-Dependent Regulation of HCV-Infection Pathogenesis" Biomolecules 4, no. 4: 885-896. https://doi.org/10.3390/biom4040885