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Diseases 2018, 6(2), 50; https://doi.org/10.3390/diseases6020050

Pancreatic Cystic Lesions: Pathogenesis and Malignant Potential

1
Department of Internal Medicine, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA
2
Division of Gastroenterology, Hepatology, and Nutrition, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA
*
Author to whom correspondence should be addressed.
Received: 15 May 2018 / Revised: 6 June 2018 / Accepted: 7 June 2018 / Published: 13 June 2018
(This article belongs to the Special Issue Pathogenesis of Pancreatic Cancer)
View Full-Text   |   Download PDF [251 KB, uploaded 13 June 2018]

Abstract

Pancreatic cancer remains one of the most lethal cancers despite extensive research. Further understanding of precursor lesions may enhance the ability to treat and prevent pancreatic cancer. Pancreatic cystic lesions (PCLs) with malignant potential include: mucinous PCLs (intraductal papillary mucinous neoplasms and mucinous cystic neoplasm), solid pseudopapillary tumors and cystic neuroendocrine tumors. This review summarizes the latest literature describing what is known about the pathogenesis and malignant potential of these PCLs, including unique epidemiological, radiological, histological, genetic and molecular characteristics. View Full-Text
Keywords: pancreatic cystic lesions; mucinous lesions; intraductal pancreatic mucinous neoplasm; mucinous cystic neoplasm; solid pseudo-papillary tumors; cystic neuroendocrine tumors; pancreatic ductal adenocarcinoma pancreatic cystic lesions; mucinous lesions; intraductal pancreatic mucinous neoplasm; mucinous cystic neoplasm; solid pseudo-papillary tumors; cystic neuroendocrine tumors; pancreatic ductal adenocarcinoma
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Pusateri, A.J.; Krishna, S.G. Pancreatic Cystic Lesions: Pathogenesis and Malignant Potential. Diseases 2018, 6, 50.

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