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Multi-Faceted Post-Transcriptional Functions of HIV-1 Rev
Molecular Virology Section, Laboratory of Molecular Microbiology, National Institutes of Allergy and Infectious Diseases, the National Institutes of Health, Bethesda, MD 20892, USA
Received: 20 June 2012; in revised form: 15 July 2012 / Accepted: 16 July 2012 / Published: 23 July 2012
Abstract: Post-transcriptional regulation of HIV-1 gene expression is largely governed by the activities of the viral Rev protein. In this minireview, the multiple post-transcriptional activities of Rev in the export of partially spliced and unspliced HIV-1 RNAs from the nucleus to the cytoplasm, in the translation of HIV-1 transcripts, and in the packaging of viral genomic RNAs are reviewed in brief.
Keywords: Rev; CRM1; DDX3; RNA export; RNA translation; RNA packaging
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Cite This Article
MDPI and ACS Style
Jeang, K.-T. Multi-Faceted Post-Transcriptional Functions of HIV-1 Rev. Biology 2012, 1, 165-174.
Jeang K-T. Multi-Faceted Post-Transcriptional Functions of HIV-1 Rev. Biology. 2012; 1(2):165-174.
Jeang, Kuan-Teh. 2012. "Multi-Faceted Post-Transcriptional Functions of HIV-1 Rev." Biology 1, no. 2: 165-174.