Next Article in Journal / Special Issue
HIV-1 Resistant CDK2-Knockdown Macrophage-Like Cells Generated from 293T Cell-Derived Human Induced Pluripotent Stem Cells
Previous Article in Journal / Special Issue
Breaking Barriers to an AIDS Model with Macaque-Tropic HIV-1 Derivatives
Article Menu

Export Article

Open AccessReview
Biology 2012, 1(2), 165-174; doi:10.3390/biology1020165

Multi-Faceted Post-Transcriptional Functions of HIV-1 Rev

Molecular Virology Section, Laboratory of Molecular Microbiology, National Institutes of Allergy and Infectious Diseases, the National Institutes of Health, Bethesda, MD 20892, USA
Received: 20 June 2012 / Revised: 15 July 2012 / Accepted: 16 July 2012 / Published: 23 July 2012
(This article belongs to the Special Issue Structural and Molecular Biology of HIV)

Abstract

Post-transcriptional regulation of HIV-1 gene expression is largely governed by the activities of the viral Rev protein. In this minireview, the multiple post-transcriptional activities of Rev in the export of partially spliced and unspliced HIV-1 RNAs from the nucleus to the cytoplasm, in the translation of HIV-1 transcripts, and in the packaging of viral genomic RNAs are reviewed in brief.
Keywords: Rev; CRM1; DDX3; RNA export; RNA translation; RNA packaging Rev; CRM1; DDX3; RNA export; RNA translation; RNA packaging
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Jeang, K.-T. Multi-Faceted Post-Transcriptional Functions of HIV-1 Rev. Biology 2012, 1, 165-174.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Biology EISSN 2079-7737 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top