Next Article in Journal
Use of a Parasitic Wasp as a Biosensor
Next Article in Special Issue
Polymerization Parameters Influencing the QCM Response Characteristics of BSA MIP
Previous Article in Journal
Recent Advances in Bioprinting and Applications for Biosensing
Previous Article in Special Issue
Hierarchical Thin Film Architectures for Enhanced Sensor Performance: Liquid Crystal-Mediated Electrochemical Synthesis of Nanostructured Imprinted Polymer Films for the Selective Recognition of Bupivacaine
Article Menu

Export Article

Open AccessArticle
Biosensors 2014, 4(2), 137-149; doi:10.3390/bios4020137

A Phage Display Screening Derived Peptide with Affinity for the Adeninyl Moiety

1
Bioorganic & Biophysical Chemistry Laboratory, Linnæus University Centre for Biomaterials Chemistry, Linnæus University, SE-39182 Kalmar, Sweden
2
Department of Chemistry & Biomedical Sciences, Linnæus University, SE-39182 Kalmar, Sweden
3
Department of Chemistry—BMC, Uppsala University, Box 576, SE-75123 Uppsala, Sweden
These authors contributed equally to this work.
*
Author to whom correspondence should be addressed.
Received: 4 March 2014 / Revised: 11 April 2014 / Accepted: 23 April 2014 / Published: 29 April 2014
(This article belongs to the Special Issue Piezoelectric Biosensors)
View Full-Text   |   Download PDF [913 KB, uploaded 29 April 2014]   |  

Abstract

Phage display screening of a surface-immobilized adenine derivative led to the identification of a heptameric peptide with selectivity for adenine as demonstrated through quartz crystal microbalance (QCM) studies. The peptide demonstrated a concentration dependent affinity for an adeninyl moiety decorated surface (KD of 968 ± 53.3 μM), which highlights the power of piezoelectric sensing in the study of weak interactions. View Full-Text
Keywords: phage display; piezoelectric sensor; QCM; adenine; peptide; molecular recognition phage display; piezoelectric sensor; QCM; adenine; peptide; molecular recognition
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Elmlund, L.; Söderberg, P.; Suriyanarayanan, S.; Nicholls, I.A. A Phage Display Screening Derived Peptide with Affinity for the Adeninyl Moiety. Biosensors 2014, 4, 137-149.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Biosensors EISSN 2079-6374 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top