Next Article in Journal
Calcination Method Synthesis of SnO2/g-C3N4 Composites for a High-Performance Ethanol Gas Sensing Application
Next Article in Special Issue
Trigger-Responsive Gene Transporters for Anticancer Therapy
Previous Article in Journal
Probing Temperature- and pH-Dependent Binding between Quantum Dots and Bovine Serum Albumin by Fluorescence Correlation Spectroscopy
Previous Article in Special Issue
siRNA Delivery Strategies: A Comprehensive Review of Recent Developments
Article Menu
Issue 5 (May) cover image

Export Article

Open AccessReview
Nanomaterials 2017, 7(5), 94; doi:10.3390/nano7050094

Recent Advances in Nanomaterials for Gene Delivery—A Review

1
Graduate Program in Plant Cellular and Molecular Biology, University of Florida, Gainesville, FL 32611, USA
2
UF Genetics Institute, University of Florida, Gainesville, FL 32611, USA
3
Department of Microbiology & Cell Science, University of Florida, Cancer/Genetics Research Complex 302, 2033 Mowry Road, Gainesville, FL 32610, USA
*
Author to whom correspondence should be addressed.
Academic Editor: Fani Sousa
Received: 16 March 2017 / Revised: 20 April 2017 / Accepted: 24 April 2017 / Published: 28 April 2017
(This article belongs to the Special Issue Nanomaterials in Gene Therapy)
View Full-Text   |   Download PDF [2445 KB, uploaded 28 April 2017]   |  

Abstract

With the rapid development of nanotechnology in the recent decade, novel DNA and RNA delivery systems for gene therapy have become available that can be used instead of viral vectors. These non-viral vectors can be made of a variety of materials, including inorganic nanoparticles, carbon nanotubes, liposomes, protein and peptide-based nanoparticles, as well as nanoscale polymeric materials. They have as advantages over viral vectors a decreased immune response, and additionally offer flexibility in design, allowing them to be functionalized and targeted to specific sites in a biological system with low cytotoxicity. The focus of this review is to provide an overview of novel nanotechnology-based methods to deliver DNA and small interfering RNAs into biological systems. View Full-Text
Keywords: gene delivery; nanomaterials; non-viral vectors; siRNA gene delivery; nanomaterials; non-viral vectors; siRNA
Figures

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Riley, M.K., II; Vermerris, W. Recent Advances in Nanomaterials for Gene Delivery—A Review. Nanomaterials 2017, 7, 94.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Nanomaterials EISSN 2079-4991 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top