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J. Funct. Biomater. 2018, 9(1), 8; doi:10.3390/jfb9010008

DNA-Based Single-Molecule Electronics: From Concept to Function

Department of Mechanical Engineering, University of Michigan, Ann Arbor, MI 48109, USA
Received: 20 December 2017 / Revised: 11 January 2018 / Accepted: 15 January 2018 / Published: 17 January 2018
(This article belongs to the Special Issue Journal of Functional Biomaterials: Feature Papers 2016)


Beyond being the repository of genetic information, DNA is playing an increasingly important role as a building block for molecular electronics. Its inherent structural and molecular recognition properties render it a leading candidate for molecular electronics applications. The structural stability, diversity and programmability of DNA provide overwhelming freedom for the design and fabrication of molecular-scale devices. In the past two decades DNA has therefore attracted inordinate amounts of attention in molecular electronics. This review gives a brief survey of recent experimental progress in DNA-based single-molecule electronics with special focus on single-molecule conductance and I–V characteristics of individual DNA molecules. Existing challenges and exciting future opportunities are also discussed. View Full-Text
Keywords: DNA; molecular electronics; charge transport; molecular junctions; single-molecule conductance; I–V characteristics DNA; molecular electronics; charge transport; molecular junctions; single-molecule conductance; I–V characteristics

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Wang, K. DNA-Based Single-Molecule Electronics: From Concept to Function. J. Funct. Biomater. 2018, 9, 8.

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