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J. Funct. Biomater. 2015, 6(1), 33-49; doi:10.3390/jfb6010033

Anticancer and Anti-Inflammatory Properties of Chitin and Chitosan Oligosaccharides

Department of Veterinary Clinical Medicine, School of Veterinary Medicine, Tottori University, 4-101 Koyama-minami, Tottori 680-8553, Japan
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Academic Editor: Francesco Puoci
Received: 4 December 2014 / Accepted: 9 January 2015 / Published: 14 January 2015
(This article belongs to the Special Issue Biomedical Applications of Chitin and Chitosan)
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Abstract

Previous reports indicate that N-acetyl-d-glucosamine oligomers (chitin oligosaccharide; NACOS) and d-glucosamine oligomers (chitosan oligosaccharide; COS) have various biological activities, especially against cancer and inflammation. In this review, we have summarized the findings of previous investigations that have focused on anticancer or anti-inflammatory properties of NACOS and COS. Moreover, we have introduced recent evaluation of NACOS and COS as functional foods against cancer and inflammatory disease. View Full-Text
Keywords: oligomers; glucosamine; N-acetyl-d-glucosamine; chitin; chitosan; cancer; anti-inflammatory; inflammatory bowel disease oligomers; glucosamine; N-acetyl-d-glucosamine; chitin; chitosan; cancer; anti-inflammatory; inflammatory bowel disease
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Azuma, K.; Osaki, T.; Minami, S.; Okamoto, Y. Anticancer and Anti-Inflammatory Properties of Chitin and Chitosan Oligosaccharides. J. Funct. Biomater. 2015, 6, 33-49.

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